Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro

• Autor(a) principal: Andrade, Yamaara Braga
• Data de Publicação: 2016
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFS
• Texto Completo: http://ri.ufs.br/jspui/handle/riufs/10392
• topic: Farmácia; Ensino de farmácia; Antioxidantes; Lamiaceae; Flavonóides; Fenóis; Hyptis fruticosa; Antioxidant activity; CIENCIAS BIOLOGICAS::FARMACOLOGIA::FARMACOLOGIA GERAL

Hyptis fruticosa is a sub-shrub belonging to the Lamiaceae family, commonly found in the Brazilian northeast coast and popularly used as a medicinal plant in the treatment for pain and other conditions. However, there are few reports on the biological activity of H. fruticosa and there are no reports of studies with its stem. On the context, this study is to provide the antioxidant profile in vitro of the Hyptis fruticosa stem ethanol extract (EEHF). In this study, was determined the content of total flavonoids and phenolic compounds, which showed significant concentrations in the plant. The antioxidant activity was determined by the radical scavenging of 2,2-difenil-1-picril-hidrazil (DPPH) and nitric oxide (NO), electron transfer capability by reducing potential (FRAP) and inhibition of lipid peroxidation by TBARS method, where EEHF showed good results in all tests at the concentrations tested. This study represents the first report on the antioxidant effect of Hyptis fruticosa stem and is intended to serve as support for future studies with the plant.