Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral

Detalhes bibliográficos
Autor(a) principal: Baumhardt, Raquel
Data de Publicação: 2015
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Manancial - Repositório Digital da UFSM
Texto Completo: http://repositorio.ufsm.br/handle/1/10201
Resumo: Intervertebral disc disease (IVD) is a common pathology in clinical neurology of dogs, representing 45.8% of neurological cases treated at Veterinary Hospital of the Universidade Federal de Santa Maria. The most affected segments are the thoracolumbar (T3-L3) and cranial cervical (C1-C5) of the spinal cord. The clinical sign occurs due a combination of the compressive effect of the disc material and the injury of impact on spinal cord, probably due to an extrusion. A clinical sign varies according to the affected segment of the spinal cord and the severity of the injury. It could be presented only by spinal hyperesthesia, whereas more severe injuries can lead to tetra / paraplegia with no nociception (deep pain) caudal to the lesion. Clinical management for IVD is generally indicated for dogs with hyperesthesia with or without minimal neurological deficits and consists of absolute rest in cage between four to six weeks. Surgery is the treatment of choice for dogs with severe neurological deficits (not ambulatory tetraparesis, tetraplegia, paraplegia with or without nociception in less than 48 hours) in dogs with unsuccessful of clinical management, or dog that have recurrence of disease. In contrast to the numerous studies evaluating the efficacy of surgical treatment in dogs with thoracolumbar and cervical IVD, studies demonstrating the effectiveness of conservative treatment are rare. The aim of this study was to identify dogs with presumptive diagnosis of thoracolumbar and cervical IVD who underwent clinical management and evaluate the response to therapy; and to analyze the effect of age, gender, duration of clinical signs, neurological degree and therapy, as prognostic factors in clinical outcome of the patient. Five hundred six neurological records were used to identify affected dogs (n = 379 thoracolumbar; n = 127 cervical), and was selected those patients with presumptive diagnosis of IVD submitted to clinical management as a first option. The outcome was satisfactory in 73.3% of cases of thoracolumbar IVD, and 92.7% of cases of cervical IVD, demonstrating that clinical management (cage rest, anti-inflammatory and analgesic opioid administration) is effective, especially in milder disease. Conservative treatment has a substantial rate of recurrence and neurological signs may be more severe than the first clinical presentation. The gender, age and duration of clinical signs has no prognostic effect on clinical outcomes of patients IVD of thoracolumbar and cervical, in the sample of the study.
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spelling Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebralClinical management of dogs with presumptive diagnosis of intervertebral disc diseaseExtrusãoProtrusãoDegeneração de discoHérnia de discoCãoExtrusionProtrusionDisc degenerationDisc herniationDogCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAIntervertebral disc disease (IVD) is a common pathology in clinical neurology of dogs, representing 45.8% of neurological cases treated at Veterinary Hospital of the Universidade Federal de Santa Maria. The most affected segments are the thoracolumbar (T3-L3) and cranial cervical (C1-C5) of the spinal cord. The clinical sign occurs due a combination of the compressive effect of the disc material and the injury of impact on spinal cord, probably due to an extrusion. A clinical sign varies according to the affected segment of the spinal cord and the severity of the injury. It could be presented only by spinal hyperesthesia, whereas more severe injuries can lead to tetra / paraplegia with no nociception (deep pain) caudal to the lesion. Clinical management for IVD is generally indicated for dogs with hyperesthesia with or without minimal neurological deficits and consists of absolute rest in cage between four to six weeks. Surgery is the treatment of choice for dogs with severe neurological deficits (not ambulatory tetraparesis, tetraplegia, paraplegia with or without nociception in less than 48 hours) in dogs with unsuccessful of clinical management, or dog that have recurrence of disease. In contrast to the numerous studies evaluating the efficacy of surgical treatment in dogs with thoracolumbar and cervical IVD, studies demonstrating the effectiveness of conservative treatment are rare. The aim of this study was to identify dogs with presumptive diagnosis of thoracolumbar and cervical IVD who underwent clinical management and evaluate the response to therapy; and to analyze the effect of age, gender, duration of clinical signs, neurological degree and therapy, as prognostic factors in clinical outcome of the patient. Five hundred six neurological records were used to identify affected dogs (n = 379 thoracolumbar; n = 127 cervical), and was selected those patients with presumptive diagnosis of IVD submitted to clinical management as a first option. The outcome was satisfactory in 73.3% of cases of thoracolumbar IVD, and 92.7% of cases of cervical IVD, demonstrating that clinical management (cage rest, anti-inflammatory and analgesic opioid administration) is effective, especially in milder disease. Conservative treatment has a substantial rate of recurrence and neurological signs may be more severe than the first clinical presentation. The gender, age and duration of clinical signs has no prognostic effect on clinical outcomes of patients IVD of thoracolumbar and cervical, in the sample of the study.Conselho Nacional de Desenvolvimento Científico e TecnológicoA doença do disco intervertebral (DDIV) é uma afecção frequente na clínica neurológica de cães, representando 45,8% dos casos neurológicos atendidos pelo Serviço de Neurologia do Hospital Veterinário Universitário da Universidade Federal de Santa Maria. Os locais mais acometidos pela doença são os segmentos toracolombar (T3-L3) e cervical cranial (C1-C5) da medula espinhal. A manifestação clínica ocorre devido a uma combinação do efeito compressivo do material de disco e da lesão de impacto na medula espinhal, decorrente principalmente da extrusão do disco e varia de acordo com o segmento da medula espinhal afetado e da severidade da lesão. Pode ser evidenciada apenas por hiperestesia espinhal, enquanto as lesões mais graves podem levar a tetra/paraplegia com ausência da nocicepção (dor profunda) caudal a lesão. O tratamento clínico para DDIV geralmente é indicado para cães com hiperpatia associada ou não a mínimas deficiências neurológicas e consiste em repouso absoluto em gaiola entre quatro a seis semanas. Já a cirurgia é o tratamento de eleição para cães com deficiências neurológicas graves (tetraparesia não ambulatória, tetraplegia, paraplegia com ou sem nocicepção em menos de 48 horas), em cães refratários ao tratamento clínico, ou que apresentem recidiva da doença. Em contraste com os inúmeros estudos avaliando a eficácia do tratamento cirúrgico em cães com DDIV toracolombar e cervical, estudos demonstrando a eficácia do tratamento conservativo são escassos na literatura. Diante desses fatores, o objetivo desse estudo foi identificar cães com diagnóstico presuntivo de DDIV toracolombar e cervical que foram submetidos ao tratamento clínico e avaliar a resposta à terapia instituída; além de avaliar a relação da idade, do gênero, da duração dos sinais clínicos e do tratamento de acordo com o grau neurológico como fatores prognósticos na evolução clínica desses pacientes. Foram analisados 506 registros neurológicos (n=379 toracolombar; n=127 cervical), e selecionados aqueles pacientes com diagnóstico presuntivo de DDIV submetidos ao tratamento clínico como primeira opção. A evolução clínica foi satisfatória em 73,3% dos casos de DDIV toracolombar, e 92,7% dos casos de DDIV cervical, demonstrando que o tratamento clínico com repouso absoluto, administração de anti-inflamatórios e analgésicos opióides é efetivo, principalmente em graus mais leves da doença. O tratamento conservativo apresenta um índice considerável de recidiva, cujos sinais neurológicos poderão ser mais graves do que a primeira apresentação clínica. O gênero, a idade e a duração dos sinais clínicos não apresentam efeito prognóstico na evolução clínica dos pacientes de DDIV toracolombar e cervical, na amostra estudada.Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaMazzanti, Alexandrehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4795593E6Fighera, Rafael Almeidahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4706265T2Alievi, Marcelo Mellerhttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4767491D6Baumhardt, Raquel2015-09-152015-09-152015-03-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfapplication/pdfBAUMHARDT, Raquel. CLINICAL MANAGEMENT OF DOGS WITH PRESUMPTIVE DIAGNOSIS OF INTERVERTEBRAL DISC DISEASE. 2015. 46 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2015.http://repositorio.ufsm.br/handle/1/10201porinfo:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2022-01-11T14:08:01Zoai:repositorio.ufsm.br:1/10201Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2022-01-11T14:08:01Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
Clinical management of dogs with presumptive diagnosis of intervertebral disc disease
title Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
spellingShingle Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
Baumhardt, Raquel
Extrusão
Protrusão
Degeneração de disco
Hérnia de disco
Cão
Extrusion
Protrusion
Disc degeneration
Disc herniation
Dog
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
title_full Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
title_fullStr Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
title_full_unstemmed Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
title_sort Tratamento clínico de cães com diagnóstico presuntivo de doença do disco intervertebral
author Baumhardt, Raquel
author_facet Baumhardt, Raquel
author_role author
dc.contributor.none.fl_str_mv Mazzanti, Alexandre
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4795593E6
Fighera, Rafael Almeida
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4706265T2
Alievi, Marcelo Meller
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4767491D6
dc.contributor.author.fl_str_mv Baumhardt, Raquel
dc.subject.por.fl_str_mv Extrusão
Protrusão
Degeneração de disco
Hérnia de disco
Cão
Extrusion
Protrusion
Disc degeneration
Disc herniation
Dog
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
topic Extrusão
Protrusão
Degeneração de disco
Hérnia de disco
Cão
Extrusion
Protrusion
Disc degeneration
Disc herniation
Dog
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Intervertebral disc disease (IVD) is a common pathology in clinical neurology of dogs, representing 45.8% of neurological cases treated at Veterinary Hospital of the Universidade Federal de Santa Maria. The most affected segments are the thoracolumbar (T3-L3) and cranial cervical (C1-C5) of the spinal cord. The clinical sign occurs due a combination of the compressive effect of the disc material and the injury of impact on spinal cord, probably due to an extrusion. A clinical sign varies according to the affected segment of the spinal cord and the severity of the injury. It could be presented only by spinal hyperesthesia, whereas more severe injuries can lead to tetra / paraplegia with no nociception (deep pain) caudal to the lesion. Clinical management for IVD is generally indicated for dogs with hyperesthesia with or without minimal neurological deficits and consists of absolute rest in cage between four to six weeks. Surgery is the treatment of choice for dogs with severe neurological deficits (not ambulatory tetraparesis, tetraplegia, paraplegia with or without nociception in less than 48 hours) in dogs with unsuccessful of clinical management, or dog that have recurrence of disease. In contrast to the numerous studies evaluating the efficacy of surgical treatment in dogs with thoracolumbar and cervical IVD, studies demonstrating the effectiveness of conservative treatment are rare. The aim of this study was to identify dogs with presumptive diagnosis of thoracolumbar and cervical IVD who underwent clinical management and evaluate the response to therapy; and to analyze the effect of age, gender, duration of clinical signs, neurological degree and therapy, as prognostic factors in clinical outcome of the patient. Five hundred six neurological records were used to identify affected dogs (n = 379 thoracolumbar; n = 127 cervical), and was selected those patients with presumptive diagnosis of IVD submitted to clinical management as a first option. The outcome was satisfactory in 73.3% of cases of thoracolumbar IVD, and 92.7% of cases of cervical IVD, demonstrating that clinical management (cage rest, anti-inflammatory and analgesic opioid administration) is effective, especially in milder disease. Conservative treatment has a substantial rate of recurrence and neurological signs may be more severe than the first clinical presentation. The gender, age and duration of clinical signs has no prognostic effect on clinical outcomes of patients IVD of thoracolumbar and cervical, in the sample of the study.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-15
2015-09-15
2015-03-06
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv BAUMHARDT, Raquel. CLINICAL MANAGEMENT OF DOGS WITH PRESUMPTIVE DIAGNOSIS OF INTERVERTEBRAL DISC DISEASE. 2015. 46 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2015.
http://repositorio.ufsm.br/handle/1/10201
identifier_str_mv BAUMHARDT, Raquel. CLINICAL MANAGEMENT OF DOGS WITH PRESUMPTIVE DIAGNOSIS OF INTERVERTEBRAL DISC DISEASE. 2015. 46 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2015.
url http://repositorio.ufsm.br/handle/1/10201
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
BR
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
publisher.none.fl_str_mv Universidade Federal de Santa Maria
BR
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
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