Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/34820 https://dx.doi.org/10.1111/j.1478-5153.2012.00494.x |
Resumo: | Background: Critical care nursing interventions to oral care can reduce microorganisms in the oropharynx available for translocation.Objectives: To analyse the effect of 0.12% chlorhexidine digluconate on the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens in mechanically ventilated children.Methods: A randomized, controlled and double-blinded study was performed in the paediatric intensive care unit (PICU) of a Brazilian university hospital. Exclusion criteria included child age under 28 days, pneumonia diagnosis at admission, use of tracheostomy, PICU length of stay (LOS) less than 48 h and refusal to participate. Children were randomly allocated to the interventional group (IG), in which oral care with chlorhexidine was administered, or to the placebo group (PG), which received oral care without antiseptic use. the data were analysed through Pearson's chi(2) test, Fisher's exact and ANOVA tests with significance levels set at 0.05.Results: the demographic characteristics of the 74 children were not statistically different between groups. No between-group differences in oropharyx colonization by Gram-negative pathogens were identified (p = 0.316). Pathogens were isolated in the tracheal secretions of two (10.0%) children in the PG and four (19.0%) children in the IG (p = 0.355).Conclusion: the use of chlorhexidine did not significantly influence the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens of the studied sample.Relevance to clinical practice: This study demonstrated no influence of a specific antiseptic agent on colonization profile of mechanically ventilated children in PICU. Further research in this field is necessary to promote evidence-based nursing practice on oral care of critically ill children. |
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Kusahara, Denise Miyuki [UNIFESP]Friedlander, Lais Tambelli [UNIFESP]Peterlini, Maria Angélica Sorgini [UNIFESP]Pedreira, Mavilde da Luz Gonçalves [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2016-01-24T14:27:09Z2016-01-24T14:27:09Z2012-05-01Nursing in Critical Care. Malden: Wiley Periodicals, Inc, v. 17, n. 3, p. 115-122, 2012.1362-1017https://repositorio.unifesp.br/handle/11600/34820https://dx.doi.org/10.1111/j.1478-5153.2012.00494.x10.1111/j.1478-5153.2012.00494.xWOS:000302802200004Background: Critical care nursing interventions to oral care can reduce microorganisms in the oropharynx available for translocation.Objectives: To analyse the effect of 0.12% chlorhexidine digluconate on the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens in mechanically ventilated children.Methods: A randomized, controlled and double-blinded study was performed in the paediatric intensive care unit (PICU) of a Brazilian university hospital. Exclusion criteria included child age under 28 days, pneumonia diagnosis at admission, use of tracheostomy, PICU length of stay (LOS) less than 48 h and refusal to participate. Children were randomly allocated to the interventional group (IG), in which oral care with chlorhexidine was administered, or to the placebo group (PG), which received oral care without antiseptic use. the data were analysed through Pearson's chi(2) test, Fisher's exact and ANOVA tests with significance levels set at 0.05.Results: the demographic characteristics of the 74 children were not statistically different between groups. No between-group differences in oropharyx colonization by Gram-negative pathogens were identified (p = 0.316). Pathogens were isolated in the tracheal secretions of two (10.0%) children in the PG and four (19.0%) children in the IG (p = 0.355).Conclusion: the use of chlorhexidine did not significantly influence the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens of the studied sample.Relevance to clinical practice: This study demonstrated no influence of a specific antiseptic agent on colonization profile of mechanically ventilated children in PICU. Further research in this field is necessary to promote evidence-based nursing practice on oral care of critically ill children.Universidade Federal de São Paulo, Sch Nursing, Pediat Nursing Dept, Escola Paulista Enfermagem, BR-04024002 São Paulo, BrazilHosp São Paulo, Pediat Intens Care Unit, São Paulo, BrazilUniversidade Federal de São Paulo, Sch Nursing, Pediat Nursing Dept, Escola Paulista Enfermagem, BR-04024002 São Paulo, BrazilHosp São Paulo, Pediat Intens Care Unit, São Paulo, BrazilWeb of Science115-122engWiley-BlackwellNursing in Critical Carehttp://olabout.wiley.com/WileyCDA/Section/id-406071.htmlinfo:eu-repo/semantics/openAccessInfection controlIntensive careOral hygienePaediatricsPaediatric nursingVentilator-associated pneumoniaOral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in childreninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlereponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/348202023-07-19 20:03:07.585metadata only accessoai:repositorio.unifesp.br:11600/34820Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-07-19T23:03:07Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
title |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
spellingShingle |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children Kusahara, Denise Miyuki [UNIFESP] Infection control Intensive care Oral hygiene Paediatrics Paediatric nursing Ventilator-associated pneumonia |
title_short |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
title_full |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
title_fullStr |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
title_full_unstemmed |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
title_sort |
Oral care and oropharyngeal and tracheal colonization by Gram-negative pathogens in children |
author |
Kusahara, Denise Miyuki [UNIFESP] |
author_facet |
Kusahara, Denise Miyuki [UNIFESP] Friedlander, Lais Tambelli [UNIFESP] Peterlini, Maria Angélica Sorgini [UNIFESP] Pedreira, Mavilde da Luz Gonçalves [UNIFESP] |
author_role |
author |
author2 |
Friedlander, Lais Tambelli [UNIFESP] Peterlini, Maria Angélica Sorgini [UNIFESP] Pedreira, Mavilde da Luz Gonçalves [UNIFESP] |
author2_role |
author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Kusahara, Denise Miyuki [UNIFESP] Friedlander, Lais Tambelli [UNIFESP] Peterlini, Maria Angélica Sorgini [UNIFESP] Pedreira, Mavilde da Luz Gonçalves [UNIFESP] |
dc.subject.eng.fl_str_mv |
Infection control Intensive care Oral hygiene Paediatrics Paediatric nursing Ventilator-associated pneumonia |
topic |
Infection control Intensive care Oral hygiene Paediatrics Paediatric nursing Ventilator-associated pneumonia |
description |
Background: Critical care nursing interventions to oral care can reduce microorganisms in the oropharynx available for translocation.Objectives: To analyse the effect of 0.12% chlorhexidine digluconate on the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens in mechanically ventilated children.Methods: A randomized, controlled and double-blinded study was performed in the paediatric intensive care unit (PICU) of a Brazilian university hospital. Exclusion criteria included child age under 28 days, pneumonia diagnosis at admission, use of tracheostomy, PICU length of stay (LOS) less than 48 h and refusal to participate. Children were randomly allocated to the interventional group (IG), in which oral care with chlorhexidine was administered, or to the placebo group (PG), which received oral care without antiseptic use. the data were analysed through Pearson's chi(2) test, Fisher's exact and ANOVA tests with significance levels set at 0.05.Results: the demographic characteristics of the 74 children were not statistically different between groups. No between-group differences in oropharyx colonization by Gram-negative pathogens were identified (p = 0.316). Pathogens were isolated in the tracheal secretions of two (10.0%) children in the PG and four (19.0%) children in the IG (p = 0.355).Conclusion: the use of chlorhexidine did not significantly influence the colonization of oropharyngeal and tracheal secretions by Gram-negative pathogens of the studied sample.Relevance to clinical practice: This study demonstrated no influence of a specific antiseptic agent on colonization profile of mechanically ventilated children in PICU. Further research in this field is necessary to promote evidence-based nursing practice on oral care of critically ill children. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-05-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T14:27:09Z |
dc.date.available.fl_str_mv |
2016-01-24T14:27:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Nursing in Critical Care. Malden: Wiley Periodicals, Inc, v. 17, n. 3, p. 115-122, 2012. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/34820 https://dx.doi.org/10.1111/j.1478-5153.2012.00494.x |
dc.identifier.issn.none.fl_str_mv |
1362-1017 |
dc.identifier.doi.none.fl_str_mv |
10.1111/j.1478-5153.2012.00494.x |
dc.identifier.wos.none.fl_str_mv |
WOS:000302802200004 |
identifier_str_mv |
Nursing in Critical Care. Malden: Wiley Periodicals, Inc, v. 17, n. 3, p. 115-122, 2012. 1362-1017 10.1111/j.1478-5153.2012.00494.x WOS:000302802200004 |
url |
https://repositorio.unifesp.br/handle/11600/34820 https://dx.doi.org/10.1111/j.1478-5153.2012.00494.x |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Nursing in Critical Care |
dc.rights.driver.fl_str_mv |
http://olabout.wiley.com/WileyCDA/Section/id-406071.html info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://olabout.wiley.com/WileyCDA/Section/id-406071.html |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
115-122 |
dc.publisher.none.fl_str_mv |
Wiley-Blackwell |
publisher.none.fl_str_mv |
Wiley-Blackwell |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
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1802764268727173120 |