An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1155/2014/565291 http://repositorio.unifesp.br/handle/11600/37143 |
Resumo: | The literature has identified complex aspects of intracellular host-parasite relationships, which require systematic, nonreductionist approaches and spatial/temporal information. Increasing and integrating temporal and spatial dimensions in host cell imaging have contributed to elucidating several conceptual gaps in the biology of intracellular parasites. To access and investigate complex and emergent dynamic events, it is mandatory to follow them in the context of living cells and organs, constructing scientific images with integrated high quality spatiotemporal data. This review discusses examples of how advances in microscopy have challenged established conceptual models of the intracellular life cycles of Leishmania spp. and Trypanosoma cruzi protozoan parasites. |
| id |
UFSP_1e53269c31ce8d352388df7b9cf77dec |
|---|---|
| oai_identifier_str |
oai:repositorio.unifesp.br/:11600/37143 |
| network_acronym_str |
UFSP |
| network_name_str |
Repositório Institucional da UNIFESP |
| repository_id_str |
3465 |
| spelling |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite RelationshipThe literature has identified complex aspects of intracellular host-parasite relationships, which require systematic, nonreductionist approaches and spatial/temporal information. Increasing and integrating temporal and spatial dimensions in host cell imaging have contributed to elucidating several conceptual gaps in the biology of intracellular parasites. To access and investigate complex and emergent dynamic events, it is mandatory to follow them in the context of living cells and organs, constructing scientific images with integrated high quality spatiotemporal data. This review discusses examples of how advances in microscopy have challenged established conceptual models of the intracellular life cycles of Leishmania spp. and Trypanosoma cruzi protozoan parasites.Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Hindawi Publishing CorporationUniversidade Federal de São Paulo (UNIFESP)Florentino, P. T. V. [UNIFESP]Real, F. [UNIFESP]Bonfim-Melo, A. [UNIFESP]Orikaza, C. M. [UNIFESP]Ferreira, E. R. [UNIFESP]Pessoa, C. C. [UNIFESP]Lima, B. R. [UNIFESP]Sasso, G. R. S. [UNIFESP]Mortara, R. A. [UNIFESP]2016-01-24T14:34:56Z2016-01-24T14:34:56Z2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion16application/pdfhttp://dx.doi.org/10.1155/2014/565291Biomed Research International. New York: Hindawi Publishing Corporation, 16 p., 2014.10.1155/2014/565291WOS000335777200001.pdf2314-6133http://repositorio.unifesp.br/handle/11600/37143WOS:000335777200001engBiomed Research Internationalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T04:17:08Zoai:repositorio.unifesp.br/:11600/37143Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T04:17:08Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| title |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| spellingShingle |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship Florentino, P. T. V. [UNIFESP] |
| title_short |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| title_full |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| title_fullStr |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| title_full_unstemmed |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| title_sort |
An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship |
| author |
Florentino, P. T. V. [UNIFESP] |
| author_facet |
Florentino, P. T. V. [UNIFESP] Real, F. [UNIFESP] Bonfim-Melo, A. [UNIFESP] Orikaza, C. M. [UNIFESP] Ferreira, E. R. [UNIFESP] Pessoa, C. C. [UNIFESP] Lima, B. R. [UNIFESP] Sasso, G. R. S. [UNIFESP] Mortara, R. A. [UNIFESP] |
| author_role |
author |
| author2 |
Real, F. [UNIFESP] Bonfim-Melo, A. [UNIFESP] Orikaza, C. M. [UNIFESP] Ferreira, E. R. [UNIFESP] Pessoa, C. C. [UNIFESP] Lima, B. R. [UNIFESP] Sasso, G. R. S. [UNIFESP] Mortara, R. A. [UNIFESP] |
| author2_role |
author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
| dc.contributor.author.fl_str_mv |
Florentino, P. T. V. [UNIFESP] Real, F. [UNIFESP] Bonfim-Melo, A. [UNIFESP] Orikaza, C. M. [UNIFESP] Ferreira, E. R. [UNIFESP] Pessoa, C. C. [UNIFESP] Lima, B. R. [UNIFESP] Sasso, G. R. S. [UNIFESP] Mortara, R. A. [UNIFESP] |
| description |
The literature has identified complex aspects of intracellular host-parasite relationships, which require systematic, nonreductionist approaches and spatial/temporal information. Increasing and integrating temporal and spatial dimensions in host cell imaging have contributed to elucidating several conceptual gaps in the biology of intracellular parasites. To access and investigate complex and emergent dynamic events, it is mandatory to follow them in the context of living cells and organs, constructing scientific images with integrated high quality spatiotemporal data. This review discusses examples of how advances in microscopy have challenged established conceptual models of the intracellular life cycles of Leishmania spp. and Trypanosoma cruzi protozoan parasites. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-01-01 2016-01-24T14:34:56Z 2016-01-24T14:34:56Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2014/565291 Biomed Research International. New York: Hindawi Publishing Corporation, 16 p., 2014. 10.1155/2014/565291 WOS000335777200001.pdf 2314-6133 http://repositorio.unifesp.br/handle/11600/37143 WOS:000335777200001 |
| url |
http://dx.doi.org/10.1155/2014/565291 http://repositorio.unifesp.br/handle/11600/37143 |
| identifier_str_mv |
Biomed Research International. New York: Hindawi Publishing Corporation, 16 p., 2014. 10.1155/2014/565291 WOS000335777200001.pdf 2314-6133 WOS:000335777200001 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Biomed Research International |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
16 application/pdf |
| dc.publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
| publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1814268428580552704 |