PREVALENCE of PARACOCCIDIOIDOMYCOSIS INFECTION BY INTRADERMAL REACTION in RURAL AREAS in ALFENAS, MINAS GERAIS, BRAZIL

• Autor(a) principal: Magalhaes, Evandro Monteiro de Sa
• Data de Publicação: 2014
• Outros Autores: Ribeiro, Carla de Fatima, Damaso, Carla Silva, Leomil Coelho, Luiz Felipe, Silva, Roberta Ribeiro, Ferreira, Eric Batista, Rodrigues, Maria Rita, Camargo, Zoilo Pires de [UNIFESP], Grao Velloso, Tania Regina, Cotta Malaquias, Luiz Cosme
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://repositorio.unifesp.br/handle/11600/37907; http://dx.doi.org/10.1590/S0036-46652014000400002
• topic: Paracoccidioidomycosis; Epidemiology; Health surveys; Intradermal tests

This study aimed to estimate the prevalence of paracoccidioidal infection by intradermal reaction (Delayed-Type Hypersensitivity, DTH) to Paracoccidioides brasiliensis in rural areas in Alfenas, Southern Minas Gerais (MG) State, Brazil, and to assess risk factors (gender, occupation, age, alcohol intake and smoking) associated with infection. We conducted a population-based cross-sectional study using intradermal tests with gp 43 paracoccidioidin in 542 participants, who were previously contacted by local health agents and so spontaneously attended the test. Participants underwent an interview by filling out a registration form with epidemiological data and were tested with an intradermal administration of 0.1 mL of paracoccidioidin in the left forearm. the test was read 48 hours after injection and was considered positive if induration was greater than or equal to 5 mm. Out of 542 participants, 46.67% were positive to the skin test. Prevalence increased in accordance with an increase of age. There was statistical significance only for males. Occupation, alcohol intake and smoking habits were not significantly associated with the risk of paracoccidioidomycosis infection. There is relevance of paracoccidioidomycosis infection in such rural areas, which suggests that further epidemiological and clinical studies on this mycosis should be done in the southern part of Minas Gerais State.