Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/3797 http://dx.doi.org/10.1590/S0100-879X2006005000133 |
Resumo: | Chronic obstructive pulmonary disease (COPD) is a common disease in adults over 40 years of age and has a great social and economic impact. It remains little recognized and undertreated even in developed countries. However, there are no data about its diagnosis and treatment in Brazil. The objectives of the present study were to evaluate the proportion of COPD patients who had never been diagnosed and to determine if the COPD patients who had been identified were receiving appropriate treatment. The Latin American Project for the Investigation of Obstructive Lung Disease (PLATINO) was a randomized epidemiological study of adults over 40 years living in five metropolitan areas, including São Paulo. The studied sample was randomly selected from the population after a division of the metropolitan area of São Paulo in clusters according to social characteristics. All subjects answered a standardized questionnaire on respiratory symptoms, history of smoking, previous diagnosis of lung disease, and treatments. All subjects performed spirometry. The criterion for the diagnosis of COPD was defined by a post-bronchodilator FEV1/FVC ratio lower than 0.7. A total of 918 subjects were evaluated and 144 (15.8%) met the diagnostic criterion for COPD. However, 126 individuals (87.5%) had never been diagnosed. This undiagnosed group of COPD patients had a lower proportion of subjects with respiratory symptoms than the previously diagnosed patients (88.9 vs 54.8%) and showed better lung function with greater FEV1 (86.8 ± 20.8 vs 68.5 ± 23.6% predicted) and FVC (106.6 ± 22.4 vs 92.0 ± 24.1% predicted). Among the COPD patients, only 57.3% were advised to stop smoking and 30.6% received the influenza vaccine. In addition, 82.3% did not receive any pharmacological treatment. In conclusion, COPD is underdiagnosed and a large number of COPD patients are not treated appropriately. |
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Nascimento, Oliver Augusto [UNIFESP]Camelier, Aquiles Assunção [UNIFESP]Rosa, Fernanda Warken [UNIFESP]Menezes, Ana Maria BaptistaPérez-Padilla, RogelioJardim, José Roberto [UNIFESP]Universidade Federal de São Paulo (UNIFESP)Universidade Federal da BahiaUniversidade Católica de Salvador Faculdade de Tecnologia e CiênciasUniversidade Federal de Pelotas Programa de Pós-graduação em EpidemiologiaNational Institute of Respiratory DiseasesPLATINO Group2015-06-14T13:37:00Z2015-06-14T13:37:00Z2007-07-01Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 40, n. 7, p. 887-895, 2007.0100-879Xhttp://repositorio.unifesp.br/handle/11600/3797http://dx.doi.org/10.1590/S0100-879X2006005000133S0100-879X2007000700001.pdfS0100-879X200700070000110.1590/S0100-879X2006005000133WOS:000248411200001Chronic obstructive pulmonary disease (COPD) is a common disease in adults over 40 years of age and has a great social and economic impact. It remains little recognized and undertreated even in developed countries. However, there are no data about its diagnosis and treatment in Brazil. The objectives of the present study were to evaluate the proportion of COPD patients who had never been diagnosed and to determine if the COPD patients who had been identified were receiving appropriate treatment. The Latin American Project for the Investigation of Obstructive Lung Disease (PLATINO) was a randomized epidemiological study of adults over 40 years living in five metropolitan areas, including São Paulo. The studied sample was randomly selected from the population after a division of the metropolitan area of São Paulo in clusters according to social characteristics. All subjects answered a standardized questionnaire on respiratory symptoms, history of smoking, previous diagnosis of lung disease, and treatments. All subjects performed spirometry. The criterion for the diagnosis of COPD was defined by a post-bronchodilator FEV1/FVC ratio lower than 0.7. A total of 918 subjects were evaluated and 144 (15.8%) met the diagnostic criterion for COPD. However, 126 individuals (87.5%) had never been diagnosed. This undiagnosed group of COPD patients had a lower proportion of subjects with respiratory symptoms than the previously diagnosed patients (88.9 vs 54.8%) and showed better lung function with greater FEV1 (86.8 ± 20.8 vs 68.5 ± 23.6% predicted) and FVC (106.6 ± 22.4 vs 92.0 ± 24.1% predicted). Among the COPD patients, only 57.3% were advised to stop smoking and 30.6% received the influenza vaccine. In addition, 82.3% did not receive any pharmacological treatment. In conclusion, COPD is underdiagnosed and a large number of COPD patients are not treated appropriately.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Centro de Reabilitação PulmonarUniversidade Federal da BahiaUniversidade Católica de Salvador Faculdade de Tecnologia e CiênciasUniversidade Federal de Pelotas Programa de Pós-graduação em EpidemiologiaNational Institute of Respiratory DiseasesPLATINO GroupUNIFESP, EPM, Centro de Reabilitação PulmonarSciELO887-895engAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological ResearchChronic obstructive pulmonary diseaseDiagnosisTreatmentVaccinationSmokingLatin American Project for the Investigation of Obstructive Lung DiseaseChronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS0100-879X2007000700001.pdfapplication/pdf512233${dspace.ui.url}/bitstream/11600/3797/1/S0100-879X2007000700001.pdf74fec80d7e91379843819702dee29767MD51open accessTEXTS0100-879X2007000700001.pdf.txtS0100-879X2007000700001.pdf.txtExtracted texttext/plain34310${dspace.ui.url}/bitstream/11600/3797/2/S0100-879X2007000700001.pdf.txt35b3d790c81123ba366069e7abb250a8MD52open access11600/37972023-02-15 11:05:00.295open accessoai:repositorio.unifesp.br:11600/3797Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-02-15T14:05Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
title |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
spellingShingle |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study Nascimento, Oliver Augusto [UNIFESP] Chronic obstructive pulmonary disease Diagnosis Treatment Vaccination Smoking Latin American Project for the Investigation of Obstructive Lung Disease |
title_short |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
title_full |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
title_fullStr |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
title_full_unstemmed |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
title_sort |
Chronic obstructive pulmonary disease is underdiagnosed and undertreated in São Paulo (Brazil): results of the PLATINO study |
author |
Nascimento, Oliver Augusto [UNIFESP] |
author_facet |
Nascimento, Oliver Augusto [UNIFESP] Camelier, Aquiles Assunção [UNIFESP] Rosa, Fernanda Warken [UNIFESP] Menezes, Ana Maria Baptista Pérez-Padilla, Rogelio Jardim, José Roberto [UNIFESP] |
author_role |
author |
author2 |
Camelier, Aquiles Assunção [UNIFESP] Rosa, Fernanda Warken [UNIFESP] Menezes, Ana Maria Baptista Pérez-Padilla, Rogelio Jardim, José Roberto [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade Federal da Bahia Universidade Católica de Salvador Faculdade de Tecnologia e Ciências Universidade Federal de Pelotas Programa de Pós-graduação em Epidemiologia National Institute of Respiratory Diseases PLATINO Group |
dc.contributor.author.fl_str_mv |
Nascimento, Oliver Augusto [UNIFESP] Camelier, Aquiles Assunção [UNIFESP] Rosa, Fernanda Warken [UNIFESP] Menezes, Ana Maria Baptista Pérez-Padilla, Rogelio Jardim, José Roberto [UNIFESP] |
dc.subject.eng.fl_str_mv |
Chronic obstructive pulmonary disease Diagnosis Treatment Vaccination Smoking Latin American Project for the Investigation of Obstructive Lung Disease |
topic |
Chronic obstructive pulmonary disease Diagnosis Treatment Vaccination Smoking Latin American Project for the Investigation of Obstructive Lung Disease |
description |
Chronic obstructive pulmonary disease (COPD) is a common disease in adults over 40 years of age and has a great social and economic impact. It remains little recognized and undertreated even in developed countries. However, there are no data about its diagnosis and treatment in Brazil. The objectives of the present study were to evaluate the proportion of COPD patients who had never been diagnosed and to determine if the COPD patients who had been identified were receiving appropriate treatment. The Latin American Project for the Investigation of Obstructive Lung Disease (PLATINO) was a randomized epidemiological study of adults over 40 years living in five metropolitan areas, including São Paulo. The studied sample was randomly selected from the population after a division of the metropolitan area of São Paulo in clusters according to social characteristics. All subjects answered a standardized questionnaire on respiratory symptoms, history of smoking, previous diagnosis of lung disease, and treatments. All subjects performed spirometry. The criterion for the diagnosis of COPD was defined by a post-bronchodilator FEV1/FVC ratio lower than 0.7. A total of 918 subjects were evaluated and 144 (15.8%) met the diagnostic criterion for COPD. However, 126 individuals (87.5%) had never been diagnosed. This undiagnosed group of COPD patients had a lower proportion of subjects with respiratory symptoms than the previously diagnosed patients (88.9 vs 54.8%) and showed better lung function with greater FEV1 (86.8 ± 20.8 vs 68.5 ± 23.6% predicted) and FVC (106.6 ± 22.4 vs 92.0 ± 24.1% predicted). Among the COPD patients, only 57.3% were advised to stop smoking and 30.6% received the influenza vaccine. In addition, 82.3% did not receive any pharmacological treatment. In conclusion, COPD is underdiagnosed and a large number of COPD patients are not treated appropriately. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-07-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:37:00Z |
dc.date.available.fl_str_mv |
2015-06-14T13:37:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 40, n. 7, p. 887-895, 2007. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/3797 http://dx.doi.org/10.1590/S0100-879X2006005000133 |
dc.identifier.issn.none.fl_str_mv |
0100-879X |
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S0100-879X2007000700001.pdf |
dc.identifier.scielo.none.fl_str_mv |
S0100-879X2007000700001 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-879X2006005000133 |
dc.identifier.wos.none.fl_str_mv |
WOS:000248411200001 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 40, n. 7, p. 887-895, 2007. 0100-879X S0100-879X2007000700001.pdf S0100-879X2007000700001 10.1590/S0100-879X2006005000133 WOS:000248411200001 |
url |
http://repositorio.unifesp.br/handle/11600/3797 http://dx.doi.org/10.1590/S0100-879X2006005000133 |
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eng |
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Brazilian Journal of Medical and Biological Research |
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Associação Brasileira de Divulgação Científica |
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Associação Brasileira de Divulgação Científica |
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