One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/31963 http://dx.doi.org/10.1136/bjo.2008.152579 |
Resumo: | Aim: To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction of myopia.Methods: Eighty-eight eyes of 44 patients with moderate myopia were randomised to PRK with 0.002% MMC for 1 min in one eye and LASIK in the fellow eye. the 1-year follow-up was evaluated.Results: There were no differences between LASIK and MMC-PRK eyes preoperatively. Forty-two patients completed the 1-year follow-up. MMC-PRK eyes achieved better uncorrected visual acuity (p=0.03) and better best-spectacle-corrected visual acuity (p<0.001) 1 year after surgery. SE did not differ in the two groups during follow-up (p=0.12). Clinically significant haze was not found in surface ablation eyes. LASIK eyes showed a greater higher-order aberration (p=0.01) and lower contrast sensitivity (p<0.05) than MMC-PRK eyes postoperatively. Excellent vision was reported in 64% of LASIK and 74% of MMC-PRK eyes 1 year after surgery. the corneal resistance factor and corneal hysteresis (ORA, Reichert) were higher in LASIK than in MMC-PRK eyes (p<0.01) at the last follow-up.Conclusions: Wavefront-guided PRK with 0.002% MMC was more effective than wavefront-guided LASIK for correction of moderate myopia. Further research is necessary to determine the optimal concentration, exposure time and long-term corneal side effect of MMC. |
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Wallau, Anelise Dutra [UNIFESP]Campos, M. [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2016-01-24T13:58:56Z2016-01-24T13:58:56Z2009-12-01British Journal of Ophthalmology. London: B M J Publishing Group, v. 93, n. 12, p. 1634-1638, 2009.0007-1161http://repositorio.unifesp.br/handle/11600/31963http://dx.doi.org/10.1136/bjo.2008.152579WOS000272187300020.pdf10.1136/bjo.2008.152579WOS:000272187300020Aim: To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction of myopia.Methods: Eighty-eight eyes of 44 patients with moderate myopia were randomised to PRK with 0.002% MMC for 1 min in one eye and LASIK in the fellow eye. the 1-year follow-up was evaluated.Results: There were no differences between LASIK and MMC-PRK eyes preoperatively. Forty-two patients completed the 1-year follow-up. MMC-PRK eyes achieved better uncorrected visual acuity (p=0.03) and better best-spectacle-corrected visual acuity (p<0.001) 1 year after surgery. SE did not differ in the two groups during follow-up (p=0.12). Clinically significant haze was not found in surface ablation eyes. LASIK eyes showed a greater higher-order aberration (p=0.01) and lower contrast sensitivity (p<0.05) than MMC-PRK eyes postoperatively. Excellent vision was reported in 64% of LASIK and 74% of MMC-PRK eyes 1 year after surgery. the corneal resistance factor and corneal hysteresis (ORA, Reichert) were higher in LASIK than in MMC-PRK eyes (p<0.01) at the last follow-up.Conclusions: Wavefront-guided PRK with 0.002% MMC was more effective than wavefront-guided LASIK for correction of moderate myopia. Further research is necessary to determine the optimal concentration, exposure time and long-term corneal side effect of MMC.Universidade Federal de São Paulo, Vis Inst, Dept Ophthalmol, São Paulo, BrazilUniversidade Federal de São Paulo, Vis Inst, Dept Ophthalmol, São Paulo, BrazilWeb of Science1634-1638engB M J Publishing GroupBritish Journal of OphthalmologyOne-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIKinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000272187300020.pdfapplication/pdf267268${dspace.ui.url}/bitstream/11600/31963/1/WOS000272187300020.pdf05f209fbc0ac790c1666e5f5255492baMD51open accessTEXTWOS000272187300020.pdf.txtWOS000272187300020.pdf.txtExtracted texttext/plain26680${dspace.ui.url}/bitstream/11600/31963/2/WOS000272187300020.pdf.txt2a6d12471929216c5e0801904797d348MD52open access11600/319632023-02-15 09:10:18.352open accessoai:repositorio.unifesp.br:11600/31963Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-02-15T12:10:18Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
title |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
spellingShingle |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK Wallau, Anelise Dutra [UNIFESP] |
title_short |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
title_full |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
title_fullStr |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
title_full_unstemmed |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
title_sort |
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK |
author |
Wallau, Anelise Dutra [UNIFESP] |
author_facet |
Wallau, Anelise Dutra [UNIFESP] Campos, M. [UNIFESP] |
author_role |
author |
author2 |
Campos, M. [UNIFESP] |
author2_role |
author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Wallau, Anelise Dutra [UNIFESP] Campos, M. [UNIFESP] |
description |
Aim: To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction of myopia.Methods: Eighty-eight eyes of 44 patients with moderate myopia were randomised to PRK with 0.002% MMC for 1 min in one eye and LASIK in the fellow eye. the 1-year follow-up was evaluated.Results: There were no differences between LASIK and MMC-PRK eyes preoperatively. Forty-two patients completed the 1-year follow-up. MMC-PRK eyes achieved better uncorrected visual acuity (p=0.03) and better best-spectacle-corrected visual acuity (p<0.001) 1 year after surgery. SE did not differ in the two groups during follow-up (p=0.12). Clinically significant haze was not found in surface ablation eyes. LASIK eyes showed a greater higher-order aberration (p=0.01) and lower contrast sensitivity (p<0.05) than MMC-PRK eyes postoperatively. Excellent vision was reported in 64% of LASIK and 74% of MMC-PRK eyes 1 year after surgery. the corneal resistance factor and corneal hysteresis (ORA, Reichert) were higher in LASIK than in MMC-PRK eyes (p<0.01) at the last follow-up.Conclusions: Wavefront-guided PRK with 0.002% MMC was more effective than wavefront-guided LASIK for correction of moderate myopia. Further research is necessary to determine the optimal concentration, exposure time and long-term corneal side effect of MMC. |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009-12-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T13:58:56Z |
dc.date.available.fl_str_mv |
2016-01-24T13:58:56Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
British Journal of Ophthalmology. London: B M J Publishing Group, v. 93, n. 12, p. 1634-1638, 2009. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/31963 http://dx.doi.org/10.1136/bjo.2008.152579 |
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0007-1161 |
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WOS000272187300020.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1136/bjo.2008.152579 |
dc.identifier.wos.none.fl_str_mv |
WOS:000272187300020 |
identifier_str_mv |
British Journal of Ophthalmology. London: B M J Publishing Group, v. 93, n. 12, p. 1634-1638, 2009. 0007-1161 WOS000272187300020.pdf 10.1136/bjo.2008.152579 WOS:000272187300020 |
url |
http://repositorio.unifesp.br/handle/11600/31963 http://dx.doi.org/10.1136/bjo.2008.152579 |
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eng |
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