Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/2457 http://dx.doi.org/10.1590/S0100-879X2005000400011 |
Resumo: | The objective of the present study was to evaluate the role of physical exercise as well as the influence of hydration with an isotonic sports drink on renal function in male Wistar rats. Four groups were studied over a period of 42 days: 1) control (N = 9); 2) physical exercise (Exe, N = 7); 3) isotonic drink (Drink, N = 8); 4) physical exercise + isotonic drink (Exe + Drink, N = 8). Physical exercise consisted of running on a motor-driven treadmill for 1 h/day, at 20 m/min, 5 days a week. The isotonic sports drink was a commercial solution used by athletes for rehydration after physical activity, 2 ml administered by gavage twice a day. Urine cultures were performed in all animals. Twenty-four-hour urine samples were collected in metabolic cages at the beginning and at the end of the protocol period. Urinary and plasma parameters (sodium, potassium, urea, creatinine, calcium) did not differ among groups. However, an amorphous material was observed in the bladders of animals in the Exe + Drink and Drink groups. Characterization of the material by Western blot revealed the presence of Tamm-Horsfall protein and angiotensin converting enzyme. Physical exercise and the isotonic drink did not change the plasma or urinary parameters measured. However, the isotonic drink induced the formation of intravesical matrix, suggesting a potential lithogenic risk. |
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Abreu, Nayda Parisio de [UNIFESP]Bergamaschi, Cassia Toledo [UNIFESP]Di Marco, Giovana Seno [UNIFESP]Razvickas, Clara Versolato [UNIFESP]Schor, Nestor [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2015-06-14T13:31:30Z2015-06-14T13:31:30Z2005-04-01Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 38, n. 4, p. 577-582, 2005.0100-879Xhttp://repositorio.unifesp.br/handle/11600/2457http://dx.doi.org/10.1590/S0100-879X2005000400011S0100-879X2005000400011.pdfS0100-879X200500040001110.1590/S0100-879X2005000400011WOS:000228962700011The objective of the present study was to evaluate the role of physical exercise as well as the influence of hydration with an isotonic sports drink on renal function in male Wistar rats. Four groups were studied over a period of 42 days: 1) control (N = 9); 2) physical exercise (Exe, N = 7); 3) isotonic drink (Drink, N = 8); 4) physical exercise + isotonic drink (Exe + Drink, N = 8). Physical exercise consisted of running on a motor-driven treadmill for 1 h/day, at 20 m/min, 5 days a week. The isotonic sports drink was a commercial solution used by athletes for rehydration after physical activity, 2 ml administered by gavage twice a day. Urine cultures were performed in all animals. Twenty-four-hour urine samples were collected in metabolic cages at the beginning and at the end of the protocol period. Urinary and plasma parameters (sodium, potassium, urea, creatinine, calcium) did not differ among groups. However, an amorphous material was observed in the bladders of animals in the Exe + Drink and Drink groups. Characterization of the material by Western blot revealed the presence of Tamm-Horsfall protein and angiotensin converting enzyme. Physical exercise and the isotonic drink did not change the plasma or urinary parameters measured. However, the isotonic drink induced the formation of intravesical matrix, suggesting a potential lithogenic risk.Universidade Federal de São Paulo (UNIFESP) Departamento de Medicina Disciplina de NefrologiaUniversidade Federal de São Paulo (UNIFESP) Departamento de Farmacologia Disciplina de Fisiologia Cardiovascular e RespiratóriaUNIFESP, Depto. de Medicina Disciplina de NefrologiaUNIFESP, Depto. de Farmacologia Disciplina de Fisiologia Cardiovascular e RespiratóriaSciELO577-582engAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological ResearchRenal functionIsotonic rehydration sports drinkPhysical activityRenal stoneNephrolithiasisTamm-Horsfall proteinEffect of an isotonic rehydration sports drink and exercise on urolithiasis in ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS0100-879X2005000400011.pdfapplication/pdf453822${dspace.ui.url}/bitstream/11600/2457/1/S0100-879X2005000400011.pdfc0b5c5f8f786e98f7503eba2d1d25093MD51open accessTEXTS0100-879X2005000400011.pdf.txtS0100-879X2005000400011.pdf.txtExtracted texttext/plain22105${dspace.ui.url}/bitstream/11600/2457/2/S0100-879X2005000400011.pdf.txt933860c3cdf009279c10ce820bf04571MD52open access11600/24572021-09-30 15:48:16.709open accessoai:repositorio.unifesp.br:11600/2457Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652021-09-30T18:48:16Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
title |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
spellingShingle |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats Abreu, Nayda Parisio de [UNIFESP] Renal function Isotonic rehydration sports drink Physical activity Renal stone Nephrolithiasis Tamm-Horsfall protein |
title_short |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
title_full |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
title_fullStr |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
title_full_unstemmed |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
title_sort |
Effect of an isotonic rehydration sports drink and exercise on urolithiasis in rats |
author |
Abreu, Nayda Parisio de [UNIFESP] |
author_facet |
Abreu, Nayda Parisio de [UNIFESP] Bergamaschi, Cassia Toledo [UNIFESP] Di Marco, Giovana Seno [UNIFESP] Razvickas, Clara Versolato [UNIFESP] Schor, Nestor [UNIFESP] |
author_role |
author |
author2 |
Bergamaschi, Cassia Toledo [UNIFESP] Di Marco, Giovana Seno [UNIFESP] Razvickas, Clara Versolato [UNIFESP] Schor, Nestor [UNIFESP] |
author2_role |
author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Abreu, Nayda Parisio de [UNIFESP] Bergamaschi, Cassia Toledo [UNIFESP] Di Marco, Giovana Seno [UNIFESP] Razvickas, Clara Versolato [UNIFESP] Schor, Nestor [UNIFESP] |
dc.subject.eng.fl_str_mv |
Renal function Isotonic rehydration sports drink Physical activity Renal stone Nephrolithiasis Tamm-Horsfall protein |
topic |
Renal function Isotonic rehydration sports drink Physical activity Renal stone Nephrolithiasis Tamm-Horsfall protein |
description |
The objective of the present study was to evaluate the role of physical exercise as well as the influence of hydration with an isotonic sports drink on renal function in male Wistar rats. Four groups were studied over a period of 42 days: 1) control (N = 9); 2) physical exercise (Exe, N = 7); 3) isotonic drink (Drink, N = 8); 4) physical exercise + isotonic drink (Exe + Drink, N = 8). Physical exercise consisted of running on a motor-driven treadmill for 1 h/day, at 20 m/min, 5 days a week. The isotonic sports drink was a commercial solution used by athletes for rehydration after physical activity, 2 ml administered by gavage twice a day. Urine cultures were performed in all animals. Twenty-four-hour urine samples were collected in metabolic cages at the beginning and at the end of the protocol period. Urinary and plasma parameters (sodium, potassium, urea, creatinine, calcium) did not differ among groups. However, an amorphous material was observed in the bladders of animals in the Exe + Drink and Drink groups. Characterization of the material by Western blot revealed the presence of Tamm-Horsfall protein and angiotensin converting enzyme. Physical exercise and the isotonic drink did not change the plasma or urinary parameters measured. However, the isotonic drink induced the formation of intravesical matrix, suggesting a potential lithogenic risk. |
publishDate |
2005 |
dc.date.issued.fl_str_mv |
2005-04-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:31:30Z |
dc.date.available.fl_str_mv |
2015-06-14T13:31:30Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 38, n. 4, p. 577-582, 2005. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/2457 http://dx.doi.org/10.1590/S0100-879X2005000400011 |
dc.identifier.issn.none.fl_str_mv |
0100-879X |
dc.identifier.file.none.fl_str_mv |
S0100-879X2005000400011.pdf |
dc.identifier.scielo.none.fl_str_mv |
S0100-879X2005000400011 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-879X2005000400011 |
dc.identifier.wos.none.fl_str_mv |
WOS:000228962700011 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 38, n. 4, p. 577-582, 2005. 0100-879X S0100-879X2005000400011.pdf S0100-879X2005000400011 10.1590/S0100-879X2005000400011 WOS:000228962700011 |
url |
http://repositorio.unifesp.br/handle/11600/2457 http://dx.doi.org/10.1590/S0100-879X2005000400011 |
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eng |
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Brazilian Journal of Medical and Biological Research |
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Associação Brasileira de Divulgação Científica |
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Associação Brasileira de Divulgação Científica |
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