Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Vanessa Gomes Brand?o
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFVJM
Texto Completo: http://acervo.ufvjm.edu.br/jspui/handle/1/2507
Resumo: Texto em outro idioma: (Ingl?s) p. 50-67.
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spelling Rodrigues, Vanessa Gomes Brand?oFigueiredo, Pedro Henrique ScheidtCosta, Henrique SilveiraNeves, Camila Danielle da CunhaUniversidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)Figueiredo, Pedro Henrique Scheidt2021-04-28T18:39:59Z2021-04-28T18:39:59Z20202020-12-16RODRIGUES, Vanessa Gomes Brand?o. Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise. 2020. 67 p. Disserta??o (Mestrado em Reabilita??o e Desempenho Funcional) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2020.http://acervo.ufvjm.edu.br/jspui/handle/1/2507Texto em outro idioma: (Ingl?s) p. 50-67.Introdu??o: Pacientes com Doen?a Renal Cr?nica (DRC) dial?tica podem apresentar altera??es da fun??o ?ssea e muscular, que s?o dependentes tanto da DRC quanto do pr?prio tratamento dial?tico. Pacientes em hemodi?lise que apresentam fun??o renal residual, apresentam menores n?veis de citocinas inflamat?rias circulantes e melhores avalia??es cardiovasculares. Postula-se tamb?m que este subgrupo de pacientes apresentem uma progress?o menos acentuada da disfun??o osteomuscular. Entretanto, a influ?ncia da diurese residual sobre a fun??o ?ssea e muscular de pacientes em hemodi?lise ainda precisa ser estudada. Objetivo: Avaliar a rela??o da diurese residual com a fun??o ?ssea e muscular de pacientes com DRC em hemodi?lise. M?todos: Por meio de um estudo transversal, pacientes em hemodi?lise foram submetidos ao exame de Absormetria Radiol?gica de Dupla Energia (DEXA), para registro da densidade mineral ?ssea e do ?ndice relativo de massa muscular esquel?tica). Com base no volume de diurese coletado em 24h, os pacientes foram estratificados em an?ricos (diurese ? 100 mL/dia) ou n?o an?ricos (diurese > 100 mL/dia). Os valores de densidade mineral ?ssea foram correlacionados ao volume de diurese em 24 h pelo teste de Spearman. Os dados do DEXA e a propor??o de indiv?duos osteop?nicos e sarcop?nicos entre os grupos An?rico e N?o An?rico foram comparados pelos testes Mann Whitney e qui-quadrado, respectivamente. A influ?ncia da aus?ncia de diurese residual sobre presen?a de sarcopenia e osteopenia foram analisadas por modelos de regress?o log?stica bin?ria simples e ajustados por idade, sexo e tempo de tratamento em di?lise. Signific?ncia estat?stica foi considerada quando p < 0,05. Resultados: Noventa e dois pacientes, com m?dia de idade de 54,4 anos (IC95% 51,3 ? 57,4), foram avaliados (47 an?ricos e 45 n?o an?ricos). O volume de diurese di?rio apresentou correla??o significativa com a densidade mineral ?ssea (r=0,24; p=0,02). O grupo an?rico apresentou menor densidade mineral ?ssea (p=0,007) e maior propor??o de indiv?duos com osteopenia (p=0,025), em compara??o ao n?o an?rico. N?o houve diferen?as entre os grupos na propor??o de indiv?duos com sarcopenia (p=0,129). Pacientes an?ricos apresentaram um risco 2,77 vezes maior de apresentar sarcopenia e 2,60 vezes maior de apresentar osteopenia, independente do sexo, idade e tempo de di?lise. O sexo foi a outra vari?vel preditora para presen?a de sarcopenia, tendo o sexo masculino um risco de 3,30 vezes maior. Conclus?o: Em pacientes em hemodi?lise, a presen?a de diurese residual est? relacionada a melhor fun??o ?ssea e muscular.Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2021-04-27T20:06:07Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) vanessa_gomes_brandao_rodrigues.pdf: 1309710 bytes, checksum: af3376e36b79ee537ee6626d6295a0b3 (MD5)Approved for entry into archive by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2021-04-28T18:39:59Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) vanessa_gomes_brandao_rodrigues.pdf: 1309710 bytes, checksum: af3376e36b79ee537ee6626d6295a0b3 (MD5)Made available in DSpace on 2021-04-28T18:39:59Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) vanessa_gomes_brandao_rodrigues.pdf: 1309710 bytes, checksum: af3376e36b79ee537ee6626d6295a0b3 (MD5) Previous issue date: 2020Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2020.Introduction: Patients with Chronic Kidney Disease (CKD) on hemodialysis may present changes in bone and muscle function, which are dependent both on CKD and on the dialysis treatment itself. Hemodialysis patients who have residual renal function, have lower levels of circulating inflammatory cytokines and better cardiovascular assessments. Also, it has been postuling that this subgroup of patients has a less marked progression of musculoskeletal dysfunction. However, the influence of residual diuresis on bone and muscle function in hemodialysis patients is unknow. Objective: To evaluate the relationship between residual diuresis and bone and muscle function in hemodialysis patients. Methods: in this cross-sectional study, hemodialysis patients were submitted to Dual Energy Radiological Absormetry (DEXA), to record bone mineral density and the relative skeletal muscle mass index. Based on the volume of diuresis collected in 24 hours, patients were stratified into anuric (diuresis ? 100 mL / day) or non-anuric (diuresis > 100 mL / day). The values of bone mineral density were correlated with the volume of diuresis in 24 h using the Spearman test. DEXA data and the proportion of osteopenic and sarcopenic individuals between the Anuric and Non-Anuric groups were compared using the Mann Whitney and chi-square tests, respectively. The influence anuria on the presence of sarcopenia and osteopenia were analyzed using simple binary logistic regression models and adjusted for age, sex and length of hemodialysis treatment. Statistical significance was set in p <0.05. Results: Ninety-two patients, with a mean age of 54.4 years (95% CI 51.3 - 57.4), were evaluated (47 anuric and 45 non-anuric). The volume of diuresis showed a significant correlation with bone mineral density (r = 0.24; p = 0.02). The anuric group had lower bone mineral density (p = 0.007) and a higher proportion of individuals with osteopenia (p = 0.025), compared to non-anuric. There were no differences between groups in the proportion of individuals with sarcopenia (p = 0.129). Anuric patients were 2.77 times more likely to have sarcopenia and 2.60 times more likely to have osteopenia, regardless of gender, age and time on dialysis. Gender was the other predictive variable for the presence of sarcopenia, with males having a risk of 3.30 times greater. Conclusion: In hemodialysis patients, the presence of residual diuresis is related to better bone and muscle function.porUFVJMA concess?o da licen?a deste item refere-se ao ? termo de autoriza??o impresso assinado pelo autor, assim como na licen?a Creative Commons, com as seguintes condi??es: Na qualidade de titular dos direitos de autor da publica??o, autorizo a Universidade Federal dos Vales do Jequitinhonha e Mucuri e o IBICT a disponibilizar por meio de seus reposit?rios, sem ressarcimento dos direitos autorais, de acordo com a Lei n? 9610/98, o texto integral da obra disponibilizada, conforme permiss?es assinaladas, para fins de leitura, impress?o e/ou download, a t?tulo de divulga??o da produ??o cient?fica brasileira, e preserva??o, a partir desta data.info:eu-repo/semantics/openAccessRela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?liseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisDoen?a Renal Cr?nicaDiureseHemodi?liseSarcopeniaOsteopeniaChronic Kidney DiseaseDiuresisHemodialysisreponame:Repositório Institucional da UFVJMinstname:Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)instacron:UFVJMTEXTvanessa_gomes_brandao_rodrigues.pdf.txtvanessa_gomes_brandao_rodrigues.pdf.txtExtracted texttext/plain110916http://acervo.ufvjm.edu.br/jspui/bitstream/1/2507/6/vanessa_gomes_brandao_rodrigues.pdf.txt4984a2827dd303d4bba41afd50da4a34MD56LICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
title Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
spellingShingle Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
Rodrigues, Vanessa Gomes Brand?o
Doen?a Renal Cr?nica
Diurese
Hemodi?lise
Sarcopenia
Osteopenia
Chronic Kidney Disease
Diuresis
Hemodialysis
title_short Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
title_full Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
title_fullStr Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
title_full_unstemmed Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
title_sort Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise
author Rodrigues, Vanessa Gomes Brand?o
author_facet Rodrigues, Vanessa Gomes Brand?o
author_role author
dc.contributor.referee.none.fl_str_mv Figueiredo, Pedro Henrique Scheidt
Costa, Henrique Silveira
Neves, Camila Danielle da Cunha
dc.contributor.institution.pt_BR.fl_str_mv Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
dc.contributor.author.fl_str_mv Rodrigues, Vanessa Gomes Brand?o
dc.contributor.advisor1.fl_str_mv Figueiredo, Pedro Henrique Scheidt
contributor_str_mv Figueiredo, Pedro Henrique Scheidt
dc.subject.keyword.pt_BR.fl_str_mv Doen?a Renal Cr?nica
Diurese
Hemodi?lise
Sarcopenia
Osteopenia
topic Doen?a Renal Cr?nica
Diurese
Hemodi?lise
Sarcopenia
Osteopenia
Chronic Kidney Disease
Diuresis
Hemodialysis
dc.subject.keyword.en.fl_str_mv Chronic Kidney Disease
Diuresis
Hemodialysis
description Texto em outro idioma: (Ingl?s) p. 50-67.
publishDate 2020
dc.date.submitted.none.fl_str_mv 2020-12-16
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-04-28T18:39:59Z
dc.date.available.fl_str_mv 2021-04-28T18:39:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv RODRIGUES, Vanessa Gomes Brand?o. Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise. 2020. 67 p. Disserta??o (Mestrado em Reabilita??o e Desempenho Funcional) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2020.
dc.identifier.uri.fl_str_mv http://acervo.ufvjm.edu.br/jspui/handle/1/2507
identifier_str_mv RODRIGUES, Vanessa Gomes Brand?o. Rela??o entre diurese residual e fun??o ?ssea e muscular de pacientes com doen?a renal cr?nica em hemodi?lise. 2020. 67 p. Disserta??o (Mestrado em Reabilita??o e Desempenho Funcional) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2020.
url http://acervo.ufvjm.edu.br/jspui/handle/1/2507
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language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv UFVJM
publisher.none.fl_str_mv UFVJM
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institution UFVJM
reponame_str Repositório Institucional da UFVJM
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