Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | LOCUS Repositório Institucional da UFV |
Texto Completo: | https://doi.org/10.1007/s12603-015-0521-0 http://www.locus.ufv.br/handle/123456789/19335 |
Resumo: | To assess the potential associations of branched-chain amino acids (BCAA) consumption with central obesity (CObesity) and cardiometabolic risk factors in a population of Brazilian middle-aged men. Special attention was given to leucine intake. Cross-sectional study. Universidade Federal de Viçosa, Viçosa, Brazil. Two-hundred ninety-six middle-aged men (Age: 50.5 ± 5.0 years; Body mass index: 25.8 ± 3.5 kg/m2). Anthropometry, lifestyle features, blood biochemical parameters were assessed and dietary intake was estimated by a food frequency questionnaire. Participants were classified by the occurrence of CObesity, hypertriglyceridemia (HTG), hypertriglyceridemic waist phenotype (HWP) and metabolic syndrome (MetS). Subjects in the BCAA highest tertile (≥0.17 g/kg/d) presented lower occurrence of CObesity (36.0% vs 72.4%, P<0.01, z=−5.10), HTG (17.0% vs 30.6% P<0.032, z=−2.32), HWP (23.0% vs 46.9%, P<0.01, z=−3.57) and MetS (19.0% vs 34.7%, P<0.01, z=−2.57). They also exhibited lower values for Castelli index (total cholesterol:HDL-c) and triglycerides: HDL-c ratio than those in the first tertile, regardless of interfering factors (i.e. habitual physical activity, work position, smoking habit, and energy intake). Interestingly, leucine consumption showed similar associations with cardiometabolic risk factors, as compared to BCAA consumption (P<0.05). BCAA consumption was cross-sectionally and negatively associated with relevant cardiometabolic risk factors in a population of Brazilian middle-aged men. The content of leucine in BCAA consumption may have contributed to such relationship. |
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Cocate, P. G.Natali, A. J.Oliveira, A. deAlfenas, R. C.Hermsdorff, H. H. M.2018-05-04T13:44:24Z2018-05-04T13:44:24Z2014-11-1817604788https://doi.org/10.1007/s12603-015-0521-0http://www.locus.ufv.br/handle/123456789/19335To assess the potential associations of branched-chain amino acids (BCAA) consumption with central obesity (CObesity) and cardiometabolic risk factors in a population of Brazilian middle-aged men. Special attention was given to leucine intake. Cross-sectional study. Universidade Federal de Viçosa, Viçosa, Brazil. Two-hundred ninety-six middle-aged men (Age: 50.5 ± 5.0 years; Body mass index: 25.8 ± 3.5 kg/m2). Anthropometry, lifestyle features, blood biochemical parameters were assessed and dietary intake was estimated by a food frequency questionnaire. Participants were classified by the occurrence of CObesity, hypertriglyceridemia (HTG), hypertriglyceridemic waist phenotype (HWP) and metabolic syndrome (MetS). Subjects in the BCAA highest tertile (≥0.17 g/kg/d) presented lower occurrence of CObesity (36.0% vs 72.4%, P<0.01, z=−5.10), HTG (17.0% vs 30.6% P<0.032, z=−2.32), HWP (23.0% vs 46.9%, P<0.01, z=−3.57) and MetS (19.0% vs 34.7%, P<0.01, z=−2.57). They also exhibited lower values for Castelli index (total cholesterol:HDL-c) and triglycerides: HDL-c ratio than those in the first tertile, regardless of interfering factors (i.e. habitual physical activity, work position, smoking habit, and energy intake). Interestingly, leucine consumption showed similar associations with cardiometabolic risk factors, as compared to BCAA consumption (P<0.05). BCAA consumption was cross-sectionally and negatively associated with relevant cardiometabolic risk factors in a population of Brazilian middle-aged men. The content of leucine in BCAA consumption may have contributed to such relationship.engThe journal of nutrition, health & agingv. 19, Issue 7, p. 771–777, August 2015Serdi and Springer-Verlag Franceinfo:eu-repo/semantics/openAccessAmino acidsCentral obesityMetabolic syndromeCardiometabolic risk factorsConsumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intakeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALartigo.pdfartigo.pdfTexto completoapplication/pdf267163https://locus.ufv.br//bitstream/123456789/19335/1/artigo.pdffdf0647c76e695c8814243897e5845beMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://locus.ufv.br//bitstream/123456789/19335/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILartigo.pdf.jpgartigo.pdf.jpgIM Thumbnailimage/jpeg7271https://locus.ufv.br//bitstream/123456789/19335/3/artigo.pdf.jpg9db8c72b93355c1c99c1d026615e0ca6MD53123456789/193352018-05-04 23:00:37.077oai:locus.ufv.br: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Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452018-05-05T02:00:37LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false |
dc.title.en.fl_str_mv |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
title |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
spellingShingle |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake Cocate, P. G. Amino acids Central obesity Metabolic syndrome Cardiometabolic risk factors |
title_short |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
title_full |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
title_fullStr |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
title_full_unstemmed |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
title_sort |
Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake |
author |
Cocate, P. G. |
author_facet |
Cocate, P. G. Natali, A. J. Oliveira, A. de Alfenas, R. C. Hermsdorff, H. H. M. |
author_role |
author |
author2 |
Natali, A. J. Oliveira, A. de Alfenas, R. C. Hermsdorff, H. H. M. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Cocate, P. G. Natali, A. J. Oliveira, A. de Alfenas, R. C. Hermsdorff, H. H. M. |
dc.subject.pt-BR.fl_str_mv |
Amino acids Central obesity Metabolic syndrome Cardiometabolic risk factors |
topic |
Amino acids Central obesity Metabolic syndrome Cardiometabolic risk factors |
description |
To assess the potential associations of branched-chain amino acids (BCAA) consumption with central obesity (CObesity) and cardiometabolic risk factors in a population of Brazilian middle-aged men. Special attention was given to leucine intake. Cross-sectional study. Universidade Federal de Viçosa, Viçosa, Brazil. Two-hundred ninety-six middle-aged men (Age: 50.5 ± 5.0 years; Body mass index: 25.8 ± 3.5 kg/m2). Anthropometry, lifestyle features, blood biochemical parameters were assessed and dietary intake was estimated by a food frequency questionnaire. Participants were classified by the occurrence of CObesity, hypertriglyceridemia (HTG), hypertriglyceridemic waist phenotype (HWP) and metabolic syndrome (MetS). Subjects in the BCAA highest tertile (≥0.17 g/kg/d) presented lower occurrence of CObesity (36.0% vs 72.4%, P<0.01, z=−5.10), HTG (17.0% vs 30.6% P<0.032, z=−2.32), HWP (23.0% vs 46.9%, P<0.01, z=−3.57) and MetS (19.0% vs 34.7%, P<0.01, z=−2.57). They also exhibited lower values for Castelli index (total cholesterol:HDL-c) and triglycerides: HDL-c ratio than those in the first tertile, regardless of interfering factors (i.e. habitual physical activity, work position, smoking habit, and energy intake). Interestingly, leucine consumption showed similar associations with cardiometabolic risk factors, as compared to BCAA consumption (P<0.05). BCAA consumption was cross-sectionally and negatively associated with relevant cardiometabolic risk factors in a population of Brazilian middle-aged men. The content of leucine in BCAA consumption may have contributed to such relationship. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-11-18 |
dc.date.accessioned.fl_str_mv |
2018-05-04T13:44:24Z |
dc.date.available.fl_str_mv |
2018-05-04T13:44:24Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.1007/s12603-015-0521-0 http://www.locus.ufv.br/handle/123456789/19335 |
dc.identifier.issn.none.fl_str_mv |
17604788 |
identifier_str_mv |
17604788 |
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https://doi.org/10.1007/s12603-015-0521-0 http://www.locus.ufv.br/handle/123456789/19335 |
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eng |
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eng |
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v. 19, Issue 7, p. 771–777, August 2015 |
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Serdi and Springer-Verlag France info:eu-repo/semantics/openAccess |
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Serdi and Springer-Verlag France |
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openAccess |
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The journal of nutrition, health & aging |
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The journal of nutrition, health & aging |
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