Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian journal of oral sciences (Online) |
Texto Completo: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999 |
Resumo: | The purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to pulpotomies. The antibiotic paste (CTZ) was prepared with chloramphenicol, tetracycline, zinc oxide and eugenol. After 6, 8, 9 and 10 months post-pulpotomy the dogs were sacrificed. Histological analysis of the teeth revealed an intense inflammatory process in the coronal pulp at 6 months after pulpotomy, with inflammatory cells dispersed throughout the entire apical region in this period. This process became partially reduced at 8 and 9 months after pulpotomy, and totally disappeared by the end of the experiment, at 10 months. In conclusion, the endodontic treatment with this antibiotic paste seemed to be biocompatible under the present experimental conditions. However, further clinical studies are necessary to assure that this paste is safe for use in pulpotomies in children. |
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Brazilian journal of oral sciences (Online) |
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Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogsPulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility testsOdontologiaThe purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to pulpotomies. The antibiotic paste (CTZ) was prepared with chloramphenicol, tetracycline, zinc oxide and eugenol. After 6, 8, 9 and 10 months post-pulpotomy the dogs were sacrificed. Histological analysis of the teeth revealed an intense inflammatory process in the coronal pulp at 6 months after pulpotomy, with inflammatory cells dispersed throughout the entire apical region in this period. This process became partially reduced at 8 and 9 months after pulpotomy, and totally disappeared by the end of the experiment, at 10 months. In conclusion, the endodontic treatment with this antibiotic paste seemed to be biocompatible under the present experimental conditions. However, further clinical studies are necessary to assure that this paste is safe for use in pulpotomies in children.Universidade Estadual de Campinas2016-01-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/864299910.20396/bjos.v6i22.8642999Brazilian Journal of Oral Sciences; v. 6 n. 22 (2007): Ju./Sept; 1397-1401Brazilian Journal of Oral Sciences; Vol. 6 No. 22 (2007): Ju./Sept; 1397-14011677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999/10554Bruno, Glaucenira de BarrosAlves, Ana Paula NunesMenezes, Valdenice AparecidaMaia, Maria Cristina GermanoBruno, José AfonsoViana, Glauce Socorro de Barrosinfo:eu-repo/semantics/openAccess2016-02-25T09:25:40Zoai:ojs.periodicos.sbu.unicamp.br:article/8642999Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2016-02-25T09:25:40Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
dc.title.none.fl_str_mv |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
title |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
spellingShingle |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs Bruno, Glaucenira de Barros Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests Odontologia |
title_short |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
title_full |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
title_fullStr |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
title_full_unstemmed |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
title_sort |
Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
author |
Bruno, Glaucenira de Barros |
author_facet |
Bruno, Glaucenira de Barros Alves, Ana Paula Nunes Menezes, Valdenice Aparecida Maia, Maria Cristina Germano Bruno, José Afonso Viana, Glauce Socorro de Barros |
author_role |
author |
author2 |
Alves, Ana Paula Nunes Menezes, Valdenice Aparecida Maia, Maria Cristina Germano Bruno, José Afonso Viana, Glauce Socorro de Barros |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Bruno, Glaucenira de Barros Alves, Ana Paula Nunes Menezes, Valdenice Aparecida Maia, Maria Cristina Germano Bruno, José Afonso Viana, Glauce Socorro de Barros |
dc.subject.por.fl_str_mv |
Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests Odontologia |
topic |
Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests Odontologia |
description |
The purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to pulpotomies. The antibiotic paste (CTZ) was prepared with chloramphenicol, tetracycline, zinc oxide and eugenol. After 6, 8, 9 and 10 months post-pulpotomy the dogs were sacrificed. Histological analysis of the teeth revealed an intense inflammatory process in the coronal pulp at 6 months after pulpotomy, with inflammatory cells dispersed throughout the entire apical region in this period. This process became partially reduced at 8 and 9 months after pulpotomy, and totally disappeared by the end of the experiment, at 10 months. In conclusion, the endodontic treatment with this antibiotic paste seemed to be biocompatible under the present experimental conditions. However, further clinical studies are necessary to assure that this paste is safe for use in pulpotomies in children. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-01-21 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999 10.20396/bjos.v6i22.8642999 |
url |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999 |
identifier_str_mv |
10.20396/bjos.v6i22.8642999 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999/10554 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Oral Sciences; v. 6 n. 22 (2007): Ju./Sept; 1397-1401 Brazilian Journal of Oral Sciences; Vol. 6 No. 22 (2007): Ju./Sept; 1397-1401 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
instname_str |
Universidade Estadual de Campinas (UNICAMP) |
instacron_str |
UNICAMP |
institution |
UNICAMP |
reponame_str |
Brazilian journal of oral sciences (Online) |
collection |
Brazilian journal of oral sciences (Online) |
repository.name.fl_str_mv |
Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
repository.mail.fl_str_mv |
brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
_version_ |
1800216401198186496 |