Resistance training and hematological responses: a case report with a patient with severe aplastic anemia

Detalhes bibliográficos
Autor(a) principal: Câmara de Almeida, Daniel
Data de Publicação: 2023
Outros Autores: Lacerda Oliveira Rios, Wellington, Janssen Gomes da Cruz, Carlos, Montecelli, Eduardo, Sebastião, Emerson, Sousa da Silva, Renato André
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Ciências da Saúde Ceuma
Texto Completo: https://revcsaudeceuma.emnuvens.com.br/revista/article/view/4
Resumo: Aplastic anemia is a hematopoietic dysfunction that compromises pluripotent cells; the phenomenon that gives rise to the multiplication and maturation of the precursor or primordial cells of blood cells. It is commonly treated with immunosuppressive therapy and/or halogenic bone marrow transplantation. However, despite the comorbidities of aplastic anemia, studies associating physiological changes related to regular physical exercise are still scarce, possibly due to the low prevalence of the disease. Thus, we describe here the impact of a resistance training program on different hematological markers in a patient with severe aplastic anemia. A 39-year-old white male diagnosed with aplastic anemia 22 years ago underwent 12 weeks of resistance training. Different hematological markers were analyzed before and after 7 and 12 weeks of intervention. After the intervention an increase in reticulocytes and several other blood components were observed, the values of which remained within normal limits. In addition, there was a reduction in transaminases and liver enzymes that mark canalicular lesions, proving an improved liver condition. We conclude that after 12 weeks of strength training the patient presented positive changes in different hematological markers, such as erythrocytes, hemoglobin, hematocrit, neutrophils, and leukocytes, suggesting a positive effect of resistance training on the patient's clinical picture associated with the natural course of disease treatment.
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spelling Resistance training and hematological responses: a case report with a patient with severe aplastic anemiaTreinamento de força e respostas hematológicas: relato de caso de um paciente com anemia aplástica graveAnemia aplásticaTreinamento resistidoMarcadores hematólogicosAplastic anemiaResistance trainingHematological markersAplastic anemia is a hematopoietic dysfunction that compromises pluripotent cells; the phenomenon that gives rise to the multiplication and maturation of the precursor or primordial cells of blood cells. It is commonly treated with immunosuppressive therapy and/or halogenic bone marrow transplantation. However, despite the comorbidities of aplastic anemia, studies associating physiological changes related to regular physical exercise are still scarce, possibly due to the low prevalence of the disease. Thus, we describe here the impact of a resistance training program on different hematological markers in a patient with severe aplastic anemia. A 39-year-old white male diagnosed with aplastic anemia 22 years ago underwent 12 weeks of resistance training. Different hematological markers were analyzed before and after 7 and 12 weeks of intervention. After the intervention an increase in reticulocytes and several other blood components were observed, the values of which remained within normal limits. In addition, there was a reduction in transaminases and liver enzymes that mark canalicular lesions, proving an improved liver condition. We conclude that after 12 weeks of strength training the patient presented positive changes in different hematological markers, such as erythrocytes, hemoglobin, hematocrit, neutrophils, and leukocytes, suggesting a positive effect of resistance training on the patient's clinical picture associated with the natural course of disease treatment.A anemia aplástica é uma disfunção hematopoiética que compromete células pluripotenciais; fenômeno que dá origem a multiplicação e maturação das células precursoras ou primordiais das células sanguíneas. É comumente tratada com terapia imunossupressora e/ou transplante de medula óssea halogênica. No entanto, apesar das comorbidades da anemia aplástica, ainda são escassos os estudos que associam alterações fisiológicas relacionadas à prática regular do exercício físico, possivelmente pela baixa prevalência da doença. Deste modo, descreve-se aqui os efeitos de um programa de treinamento resistido sobre diferentes marcadores hematológicos em um paciente com anemia aplástica grave. Um homem branco com 39 anos, diagnosticado com anemia aplástica há 22 anos foi submetido a 12 semanas de treinamento resistido. Diferentes marcadores hematológicos foram analisados antes e após 7 e 12 semanas de intervenção. Após a intervenção foi observado um aumento dos reticulócitos e de diversos outros componentes do sangue, cujo valores permaneceram dentro dos limites de normalidade. Adicionalmente, houve uma redução em transaminases e enzimas hepáticas marcadoras de lesões canalicular, indicando uma melhor condição hepática. Conclui-se que após 12 semanas de treinamento de força o paciente apresentou alterações positivas em diferentes marcadores hematológicos, como eritrócitos, hemoglobina, hematócrito, neutrófilos, e leucócitos, o que sugere um efeito positivo do treinamento resistido sobre o quadro clínico do paciente associadamente ao curso natural do tratamento da doença.Centro Universitário Euro-Americano - UNIEURO2023-10-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos Paresapplication/pdfhttps://revcsaudeceuma.emnuvens.com.br/revista/article/view/410.61695/rcs.v1i1.4Revista Ciências da Saúde Ceuma; Vol. 1 No. 1 (2023); 52-60Revista Ciências da Saúde Ceuma; v. 1 n. 1 (2023); 52-602965-606010.61695/rcs.v1i1reponame:Revista Ciências da Saúde Ceumainstname:Centro Universitário Euro-Americano (Unieuro)instacron:UNIEUROporhttps://revcsaudeceuma.emnuvens.com.br/revista/article/view/4/13Copyright (c) 2023 Daniel Câmara de Almeida, Wellington Lacerda Oliveira Rios, Carlos Janssen Gomes da Cruz, Eduardo Montecelli, Emerson Sebastião, Renato André Sousa da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCâmara de Almeida, DanielLacerda Oliveira Rios, WellingtonJanssen Gomes da Cruz, CarlosMontecelli, EduardoSebastião, EmersonSousa da Silva, Renato André2023-11-27T13:13:11Zoai:ojs.revcsaudeceuma.emnuvens.com.br:article/4Revistahttps://revcsaudeceuma.emnuvens.com.br/revistaPRIhttps://revcsaudeceuma.emnuvens.com.br/revista/oaictomaz@ceuma.br || issac.lara@unieuro.edu.br2965-60602965-6060opendoar:2023-11-27T13:13:11Revista Ciências da Saúde Ceuma - Centro Universitário Euro-Americano (Unieuro)false
dc.title.none.fl_str_mv Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
Treinamento de força e respostas hematológicas: relato de caso de um paciente com anemia aplástica grave
title Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
spellingShingle Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
Câmara de Almeida, Daniel
Anemia aplástica
Treinamento resistido
Marcadores hematólogicos
Aplastic anemia
Resistance training
Hematological markers
title_short Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
title_full Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
title_fullStr Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
title_full_unstemmed Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
title_sort Resistance training and hematological responses: a case report with a patient with severe aplastic anemia
author Câmara de Almeida, Daniel
author_facet Câmara de Almeida, Daniel
Lacerda Oliveira Rios, Wellington
Janssen Gomes da Cruz, Carlos
Montecelli, Eduardo
Sebastião, Emerson
Sousa da Silva, Renato André
author_role author
author2 Lacerda Oliveira Rios, Wellington
Janssen Gomes da Cruz, Carlos
Montecelli, Eduardo
Sebastião, Emerson
Sousa da Silva, Renato André
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Câmara de Almeida, Daniel
Lacerda Oliveira Rios, Wellington
Janssen Gomes da Cruz, Carlos
Montecelli, Eduardo
Sebastião, Emerson
Sousa da Silva, Renato André
dc.subject.por.fl_str_mv Anemia aplástica
Treinamento resistido
Marcadores hematólogicos
Aplastic anemia
Resistance training
Hematological markers
topic Anemia aplástica
Treinamento resistido
Marcadores hematólogicos
Aplastic anemia
Resistance training
Hematological markers
description Aplastic anemia is a hematopoietic dysfunction that compromises pluripotent cells; the phenomenon that gives rise to the multiplication and maturation of the precursor or primordial cells of blood cells. It is commonly treated with immunosuppressive therapy and/or halogenic bone marrow transplantation. However, despite the comorbidities of aplastic anemia, studies associating physiological changes related to regular physical exercise are still scarce, possibly due to the low prevalence of the disease. Thus, we describe here the impact of a resistance training program on different hematological markers in a patient with severe aplastic anemia. A 39-year-old white male diagnosed with aplastic anemia 22 years ago underwent 12 weeks of resistance training. Different hematological markers were analyzed before and after 7 and 12 weeks of intervention. After the intervention an increase in reticulocytes and several other blood components were observed, the values of which remained within normal limits. In addition, there was a reduction in transaminases and liver enzymes that mark canalicular lesions, proving an improved liver condition. We conclude that after 12 weeks of strength training the patient presented positive changes in different hematological markers, such as erythrocytes, hemoglobin, hematocrit, neutrophils, and leukocytes, suggesting a positive effect of resistance training on the patient's clinical picture associated with the natural course of disease treatment.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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Artigo avaliado pelos Pares
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url https://revcsaudeceuma.emnuvens.com.br/revista/article/view/4
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dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://revcsaudeceuma.emnuvens.com.br/revista/article/view/4/13
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro Universitário Euro-Americano - UNIEURO
publisher.none.fl_str_mv Centro Universitário Euro-Americano - UNIEURO
dc.source.none.fl_str_mv Revista Ciências da Saúde Ceuma; Vol. 1 No. 1 (2023); 52-60
Revista Ciências da Saúde Ceuma; v. 1 n. 1 (2023); 52-60
2965-6060
10.61695/rcs.v1i1
reponame:Revista Ciências da Saúde Ceuma
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institution UNIEURO
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collection Revista Ciências da Saúde Ceuma
repository.name.fl_str_mv Revista Ciências da Saúde Ceuma - Centro Universitário Euro-Americano (Unieuro)
repository.mail.fl_str_mv ctomaz@ceuma.br || issac.lara@unieuro.edu.br
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