Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/38919 |
Resumo: | Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam. |
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Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022Consumo de benzodiacepinas en la ciudad de Belém-PA: estudio comparativo del primer semestre de 2020 a 2022Consumo de benzodiazepínicos no município de Belém-PA: estudo comparativo do primeiro semestre dos anos de 2020 a 2022BenzodiazepínicosDroga psicotrópicaPerfil de consumoIdosos.BenzodiazepinasPsicofármacoPerfil de ConsumoAdulto mayor.BenzodiazepinesPsychotropic drugConsumption profileElderly.Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam.Las benzodiazepinas (BZD’s) son fármacos psicoactivos que actúan como moduladores alostéricos (agonistas) del receptor del ácido γ-aminobutírico (GABA-A) tipo A en el sistema nervioso central. En la práctica clínica, estos fármacos se utilizan y prescriben a menudo en el tratamiento de la ansiedad, el insomnio y la depresión. Debido a sus diversas acciones farmacológicas y al uso prolongado, lo ubica entre los cinco medicamentos más vendidos en Brasil. La falta de información sobre las consecuencias del uso irracional aumenta la vulnerabilidad a generar dependencia. Por lo tanto, este estudio buscó analizar el consumo y la distribución de benzodiazepinas en la ciudad de Belém - Pará. En este estudio se utilizó una encuesta observacional, longitudinal y retrospectiva, comparando la primera mitad de los años 2020 a 2022, a través del sistema SNGPC. Las variables analizadas fueron: cantidad de BZD’s por año, grupo de edad, sexo y tipo de fármaco más dispensado. Los resultados obtenidos en el estudio arrojaron que se despachó un total de 33.068 BZD’s, sumando los primeros semestres de los años 2020 al 2022, el género femenino presentó mayor prevalencia de consumo, así como el grupo etario que presentó alto consumo, estuvo entre 61 a 80 años y la BZD más recetada fue Clonazepam.Os benzodiazepínicos (BZD’s) são drogas psicoativas que atuam como moduladores alostéricos (agonistas) do receptor de ácido γ-aminobutírico tipo A (GABAA), do Sistema Nervoso Central, na prática clínica, esses medicamentos são muitos utilizados e prescritos no tratamento da ansiedade, insônia e depressão. Devido suas várias ações farmacológicas, e o uso prolongado, o torna entre os cincos fármacos mais vendidos no Brasil. A falta de informações sobre as consequências do uso irracional aumenta a vulnerabilidade em gerar dependência. Sendo assim, este estudo buscou analisar consumo e dispensação de BZD’s no município de Belém – Pará. Foi utilizado nesse estudo, uma uma pesquisa observacional, longitudinal e retrospectivo comparando o primeiro semestre dos anos de 2020 a 2022, através do sistema da SNGPC. As variáveis analisadas foram: quantidade de BZD’s por ano, faixa etária, sexo e tipo de fármaco mais dispensado. Os resultados obtidos no estudo, demonstraram que foram dispensandos um total de 33.068 BZD’s, somando os primeiros semestres dos ano de 2020 a 2022, o sexo feminino demonstrou maior prevalência de consumo, bem como, a faixa etária que apresentou elevado consumo, foi entre 61 a 80 anos de idade e o BZD mais prescrito foi o Clonazepam.Research, Society and Development2023-01-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3891910.33448/rsd-v12i2.38919Research, Society and Development; Vol. 12 No. 2; e0412238919Research, Society and Development; Vol. 12 Núm. 2; e0412238919Research, Society and Development; v. 12 n. 2; e04122389192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/38919/32640Copyright (c) 2023 Rangele Ferreira da Silva Reis; Isis de Oliveira Kosmiscky; Maria Cristiane Oliveira; Francilene Nascimento de Miranda; Robson José da Silva Cruz; Thays Chaves Araújo; Milana Rodrigues Vieira; Ester Cristina Silva dos Santos; Edson Bruno Campos Paiva; Sabrina de Carvalho Cartágeneshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReis, Rangele Ferreira da Silva Kosmiscky, Isis de Oliveira Oliveira, Maria Cristiane Miranda, Francilene Nascimento de Cruz, Robson José da Silva Araújo, Thays Chaves Vieira, Milana Rodrigues Santos, Ester Cristina Silva dos Paiva, Edson Bruno Campos Cartágenes, Sabrina de Carvalho2023-02-14T20:07:52Zoai:ojs.pkp.sfu.ca:article/38919Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-02-14T20:07:52Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 Consumo de benzodiacepinas en la ciudad de Belém-PA: estudio comparativo del primer semestre de 2020 a 2022 Consumo de benzodiazepínicos no município de Belém-PA: estudo comparativo do primeiro semestre dos anos de 2020 a 2022 |
title |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
spellingShingle |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 Reis, Rangele Ferreira da Silva Benzodiazepínicos Droga psicotrópica Perfil de consumo Idosos. Benzodiazepinas Psicofármaco Perfil de Consumo Adulto mayor. Benzodiazepines Psychotropic drug Consumption profile Elderly. |
title_short |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
title_full |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
title_fullStr |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
title_full_unstemmed |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
title_sort |
Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022 |
author |
Reis, Rangele Ferreira da Silva |
author_facet |
Reis, Rangele Ferreira da Silva Kosmiscky, Isis de Oliveira Oliveira, Maria Cristiane Miranda, Francilene Nascimento de Cruz, Robson José da Silva Araújo, Thays Chaves Vieira, Milana Rodrigues Santos, Ester Cristina Silva dos Paiva, Edson Bruno Campos Cartágenes, Sabrina de Carvalho |
author_role |
author |
author2 |
Kosmiscky, Isis de Oliveira Oliveira, Maria Cristiane Miranda, Francilene Nascimento de Cruz, Robson José da Silva Araújo, Thays Chaves Vieira, Milana Rodrigues Santos, Ester Cristina Silva dos Paiva, Edson Bruno Campos Cartágenes, Sabrina de Carvalho |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Reis, Rangele Ferreira da Silva Kosmiscky, Isis de Oliveira Oliveira, Maria Cristiane Miranda, Francilene Nascimento de Cruz, Robson José da Silva Araújo, Thays Chaves Vieira, Milana Rodrigues Santos, Ester Cristina Silva dos Paiva, Edson Bruno Campos Cartágenes, Sabrina de Carvalho |
dc.subject.por.fl_str_mv |
Benzodiazepínicos Droga psicotrópica Perfil de consumo Idosos. Benzodiazepinas Psicofármaco Perfil de Consumo Adulto mayor. Benzodiazepines Psychotropic drug Consumption profile Elderly. |
topic |
Benzodiazepínicos Droga psicotrópica Perfil de consumo Idosos. Benzodiazepinas Psicofármaco Perfil de Consumo Adulto mayor. Benzodiazepines Psychotropic drug Consumption profile Elderly. |
description |
Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-01-13 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/38919 10.33448/rsd-v12i2.38919 |
url |
https://rsdjournal.org/index.php/rsd/article/view/38919 |
identifier_str_mv |
10.33448/rsd-v12i2.38919 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/38919/32640 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 12 No. 2; e0412238919 Research, Society and Development; Vol. 12 Núm. 2; e0412238919 Research, Society and Development; v. 12 n. 2; e0412238919 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052614462930944 |