Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022

Detalhes bibliográficos
Autor(a) principal: Reis, Rangele Ferreira da Silva
Data de Publicação: 2023
Outros Autores: Kosmiscky, Isis de Oliveira, Oliveira, Maria Cristiane, Miranda, Francilene Nascimento de, Cruz, Robson José da Silva, Araújo, Thays Chaves, Vieira, Milana Rodrigues, Santos, Ester Cristina Silva dos, Paiva, Edson Bruno Campos, Cartágenes, Sabrina de Carvalho
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/38919
Resumo: Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam.
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spelling Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022Consumo de benzodiacepinas en la ciudad de Belém-PA: estudio comparativo del primer semestre de 2020 a 2022Consumo de benzodiazepínicos no município de Belém-PA: estudo comparativo do primeiro semestre dos anos de 2020 a 2022BenzodiazepínicosDroga psicotrópicaPerfil de consumoIdosos.BenzodiazepinasPsicofármacoPerfil de ConsumoAdulto mayor.BenzodiazepinesPsychotropic drugConsumption profileElderly.Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam.Las benzodiazepinas (BZD’s) son fármacos psicoactivos que actúan como moduladores alostéricos (agonistas) del receptor del ácido γ-aminobutírico (GABA-A) tipo A en el sistema nervioso central. En la práctica clínica, estos fármacos se utilizan y prescriben a menudo en el tratamiento de la ansiedad, el insomnio y la depresión. Debido a sus diversas acciones farmacológicas y al uso prolongado, lo ubica entre los cinco medicamentos más vendidos en Brasil. La falta de información sobre las consecuencias del uso irracional aumenta la vulnerabilidad a generar dependencia. Por lo tanto, este estudio buscó analizar el consumo y la distribución de benzodiazepinas en la ciudad de Belém - Pará. En este estudio se utilizó una encuesta observacional, longitudinal y retrospectiva, comparando la primera mitad de los años 2020 a 2022, a través del sistema SNGPC. Las variables analizadas fueron: cantidad de BZD’s por año, grupo de edad, sexo y tipo de fármaco más dispensado. Los resultados obtenidos en el estudio arrojaron que se despachó un total de 33.068 BZD’s, sumando los primeros semestres de los años 2020 al 2022, el género femenino presentó mayor prevalencia de consumo, así como el grupo etario que presentó alto consumo, estuvo entre 61 a 80 años y la BZD más recetada fue Clonazepam.Os benzodiazepínicos (BZD’s) são drogas psicoativas que atuam como moduladores alostéricos (agonistas) do receptor de ácido γ-aminobutírico tipo A (GABAA), do Sistema Nervoso Central, na prática clínica, esses medicamentos são muitos utilizados e prescritos no tratamento da ansiedade, insônia e depressão. Devido suas várias ações farmacológicas, e o uso prolongado, o torna entre os cincos fármacos mais vendidos no Brasil. A falta de informações sobre as consequências do uso irracional aumenta a vulnerabilidade em gerar dependência. Sendo assim, este estudo buscou analisar consumo e dispensação de BZD’s no município de Belém – Pará. Foi utilizado nesse estudo, uma uma pesquisa observacional, longitudinal e retrospectivo comparando o primeiro semestre dos anos de 2020 a 2022, através do sistema da SNGPC. As variáveis analisadas foram: quantidade de BZD’s por ano, faixa etária, sexo e tipo de fármaco mais dispensado. Os resultados obtidos no estudo, demonstraram que foram dispensandos um total de 33.068 BZD’s, somando os primeiros semestres dos ano de 2020 a 2022, o sexo feminino demonstrou maior prevalência de consumo, bem como, a faixa etária que apresentou elevado consumo, foi entre 61 a 80 anos de idade e o BZD mais prescrito foi o Clonazepam.Research, Society and Development2023-01-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3891910.33448/rsd-v12i2.38919Research, Society and Development; Vol. 12 No. 2; e0412238919Research, Society and Development; Vol. 12 Núm. 2; e0412238919Research, Society and Development; v. 12 n. 2; e04122389192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/38919/32640Copyright (c) 2023 Rangele Ferreira da Silva Reis; Isis de Oliveira Kosmiscky; Maria Cristiane Oliveira; Francilene Nascimento de Miranda; Robson José da Silva Cruz; Thays Chaves Araújo; Milana Rodrigues Vieira; Ester Cristina Silva dos Santos; Edson Bruno Campos Paiva; Sabrina de Carvalho Cartágeneshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReis, Rangele Ferreira da Silva Kosmiscky, Isis de Oliveira Oliveira, Maria Cristiane Miranda, Francilene Nascimento de Cruz, Robson José da Silva Araújo, Thays Chaves Vieira, Milana Rodrigues Santos, Ester Cristina Silva dos Paiva, Edson Bruno Campos Cartágenes, Sabrina de Carvalho2023-02-14T20:07:52Zoai:ojs.pkp.sfu.ca:article/38919Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-02-14T20:07:52Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
Consumo de benzodiacepinas en la ciudad de Belém-PA: estudio comparativo del primer semestre de 2020 a 2022
Consumo de benzodiazepínicos no município de Belém-PA: estudo comparativo do primeiro semestre dos anos de 2020 a 2022
title Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
spellingShingle Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
Reis, Rangele Ferreira da Silva
Benzodiazepínicos
Droga psicotrópica
Perfil de consumo
Idosos.
Benzodiazepinas
Psicofármaco
Perfil de Consumo
Adulto mayor.
Benzodiazepines
Psychotropic drug
Consumption profile
Elderly.
title_short Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
title_full Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
title_fullStr Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
title_full_unstemmed Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
title_sort Consumption of benzodiazepines in the city of Belém-PA: comparative study of the first semester from 2020 to 2022
author Reis, Rangele Ferreira da Silva
author_facet Reis, Rangele Ferreira da Silva
Kosmiscky, Isis de Oliveira
Oliveira, Maria Cristiane
Miranda, Francilene Nascimento de
Cruz, Robson José da Silva
Araújo, Thays Chaves
Vieira, Milana Rodrigues
Santos, Ester Cristina Silva dos
Paiva, Edson Bruno Campos
Cartágenes, Sabrina de Carvalho
author_role author
author2 Kosmiscky, Isis de Oliveira
Oliveira, Maria Cristiane
Miranda, Francilene Nascimento de
Cruz, Robson José da Silva
Araújo, Thays Chaves
Vieira, Milana Rodrigues
Santos, Ester Cristina Silva dos
Paiva, Edson Bruno Campos
Cartágenes, Sabrina de Carvalho
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reis, Rangele Ferreira da Silva
Kosmiscky, Isis de Oliveira
Oliveira, Maria Cristiane
Miranda, Francilene Nascimento de
Cruz, Robson José da Silva
Araújo, Thays Chaves
Vieira, Milana Rodrigues
Santos, Ester Cristina Silva dos
Paiva, Edson Bruno Campos
Cartágenes, Sabrina de Carvalho
dc.subject.por.fl_str_mv Benzodiazepínicos
Droga psicotrópica
Perfil de consumo
Idosos.
Benzodiazepinas
Psicofármaco
Perfil de Consumo
Adulto mayor.
Benzodiazepines
Psychotropic drug
Consumption profile
Elderly.
topic Benzodiazepínicos
Droga psicotrópica
Perfil de consumo
Idosos.
Benzodiazepinas
Psicofármaco
Perfil de Consumo
Adulto mayor.
Benzodiazepines
Psychotropic drug
Consumption profile
Elderly.
description Benzodiazepines (BZD's) psychoactive drugs that act as allosteric modulators (agonists) of the type A γ-aminobutyric acid (GABA-A) receptor in the central nervous system. In clinical practice, these drugs are often used and prescribed in the treatment of anxiety, insomnia and depression. Due to its various pharmacological actions, and prolonged use, it makes it among the five best-selling drugs in Brazil. The lack of information about the consequences of irrational use increases vulnerability to generating dependence. Therefore, this study sought to analyze the consumption and distribution of BZD’s in the city of Belém - Pará. An observational, longitudinal, and retrospective survey was used in this study, comparing the first half of the years 2020 to 2022, through the SNGPC system. The variables analyzed were amount of BZD’s per year, age group, sex and type of drug most dispensed. The results obtained in the study showed that a total of 33,068 BZD’s was dispensed, adding the first semesters of the years 2020 to 2022, the female gender showed a higher prevalence of consumption, as well as the age group that presented high consumption, was between 61 a 80 years old and the most prescribed BZD was Clonazepam.
publishDate 2023
dc.date.none.fl_str_mv 2023-01-13
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/38919
10.33448/rsd-v12i2.38919
url https://rsdjournal.org/index.php/rsd/article/view/38919
identifier_str_mv 10.33448/rsd-v12i2.38919
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/38919/32640
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 2; e0412238919
Research, Society and Development; Vol. 12 Núm. 2; e0412238919
Research, Society and Development; v. 12 n. 2; e0412238919
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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