Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/8853 |
Resumo: | The probiotic is related to a food supplement, while the live biotherapeutic products - LBPs are considered biological medicines, both contain living microorganisms with active substances that benefit the host. Enterococcus faecium has many interesting and functional properties for human and animal health, including the antimicrobial capacity, which helps in food poisoning diseases such as Campylobacteriosis. Campylobacter jejuni and C. coli species have been described in this context. Therefore, due to the need to develop alternatives to ensure the safety of products consumed by the population, this work proposes a complementary strategy to reduce or eliminate Campylobacter through the use of Enterococcus faecium EF137V, isolated from artisanal “Coalho” cheese from Pernambuco-Brazil. The analyzes were performed in vitro. Given the adverse conditions, such as acid pH and the presence of bile salts, in which EF137V was exposed, it was found that the bacteria showed resistance to gastrointestinal conditions, adherence to epithelial cells, antimicrobial activity by its metabolic compounds against reference strains of C. jejuni and C. coli, as well as antagonistic activity, which suggests that both species will not be able to grow disorderly in the host's intestinal microbiota, thus being able to control these microorganisms in the bacterial community in broilers and preventing new infections in humans. It can be concluded that the EF137V is a promising PVB and probiotic, presenting great capacity for biotechnology applications. |
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Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter speciesEnterococcus faecium EF137V: una nueva fuente estratégica para el control de la salud humana y animal contra especies de CampylobacterEnterococcus faecium EF137V: uma nova fonte estratégica para o controle da saúde humana e animal contra espécies de CampylobacterProbióticosEnterococcus faeciumCampylobacter jejuniCampylobacter coliBiotecnologia.ProbióticosEnterococcus faeciumCampylobacter jejuniCampylobacter coliBiotecnología.ProbioticsEnterococcus faeciumCampylobacter jejuniCampylobacter coliBiothecnology.The probiotic is related to a food supplement, while the live biotherapeutic products - LBPs are considered biological medicines, both contain living microorganisms with active substances that benefit the host. Enterococcus faecium has many interesting and functional properties for human and animal health, including the antimicrobial capacity, which helps in food poisoning diseases such as Campylobacteriosis. Campylobacter jejuni and C. coli species have been described in this context. Therefore, due to the need to develop alternatives to ensure the safety of products consumed by the population, this work proposes a complementary strategy to reduce or eliminate Campylobacter through the use of Enterococcus faecium EF137V, isolated from artisanal “Coalho” cheese from Pernambuco-Brazil. The analyzes were performed in vitro. Given the adverse conditions, such as acid pH and the presence of bile salts, in which EF137V was exposed, it was found that the bacteria showed resistance to gastrointestinal conditions, adherence to epithelial cells, antimicrobial activity by its metabolic compounds against reference strains of C. jejuni and C. coli, as well as antagonistic activity, which suggests that both species will not be able to grow disorderly in the host's intestinal microbiota, thus being able to control these microorganisms in the bacterial community in broilers and preventing new infections in humans. It can be concluded that the EF137V is a promising PVB and probiotic, presenting great capacity for biotechnology applications.El probiótico está relacionado con un complemento alimenticio, mientras que los productos bioterapéuticos vivos, los PBV se consideran medicamentos biológicos, ambos contienen microorganismos vivos con sustancias activas que benefician al huésped. Enterococcus faecium tiene muchas propiedades interesantes y funcionales para la salud humana y animal, incluida la capacidad antimicrobiana, que ayuda en enfermedades de intoxicación alimentaria como la campilobacteriosis. En este contexto se han descrito especies de Campylobacter jejuni y C. coli. Por lo tanto, ante la necesidad de desarrollar alternativas para asegurar la inocuidad de los productos consumidos por la población, este trabajo propone una estrategia complementaria para reducir o eliminar Campylobacter mediante el uso de Enterococcus faecium EF137V, aislado de queso “Coalho” artesanal de Pernambuco-Brasil. Los análisis se realizaron in vitro. Dadas las condiciones adversas, como pH ácido y presencia de sales biliares, en las que se expuso EF137V, se encontró que la bacteria presentaba resistencia a afecciones gastrointestinales, adherencia a células epiteliales, actividad antimicrobiana por sus compuestos metabólicos frente a cepas de referencia de C. jejuni y C. coli, así como actividad antagónica, lo que sugiere que ambas especies no podrán crecer desordenadamente en la microbiota intestinal del hospedador, pudiendo así controlar estos microorganismos en la comunidad bacteriana en pollos de engorde y prevenir nuevas infecciones en humanos. Se puede concluir que el EF137V es un PVB y probiótico prometedor, presentando gran capacidad para aplicaciones biotecnológicas.O probiótico está relacionado a um suplemento alimentar, enquanto que os produtos vivos bioterapêuticos - PVBs são considerados medicamentos biológicos, ambos contêm micro-organismos vivos com substâncias ativas e que beneficiam o hospedeiro. O Enterococcus faecium apresenta muitas propriedades interessantes e funcionais para saúde humana e animal, entre elas a capacidade antimicrobiana, que ajuda em doenças de intoxicação alimentar como a Campilobacteriose. As espécies Campylobacter jejuni e C. coli, têm sido descritas neste contexto. Portanto, pela necessidade de desenvolver alternativas que permitam garantir a segurança dos produtos consumidos pela população, este trabalho propõe uma estratégia complementar para reduzir ou eliminar o Campylobacter por meio do uso de Enterococcus faecium EF137V, isolado de queijo “Coalho” artesanal de Pernambuco-Brasil. As análises foram realizadas in vitro. Dadas as condições adversas, como pH ácido e presença de sais biliares, nas quais EF137V foi exposto, verificou-se que a bactéria apresentou resistência a condições gastrointestinais, aderência às células epiteliais, atividade antimicrobiana pelos seus compostos metabólicos contra cepas de referência de C. jejuni e C. coli, bem como atividade antagonista, o que sugere que ambas as espécies não serão capazes de crescer desordenadamente na microbiota intestinal do hospedeiro, podendo assim controlar a esses microrganismos na comunidade bacteriana em frangos de corte e evitando novas infecções em humanos. Pode-se concluir que o EF137V é um PVB e probiótico promissor, apresentando grande capacidade para aplicações de biotecnologia.Research, Society and Development2020-10-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/885310.33448/rsd-v9i10.8853Research, Society and Development; Vol. 9 No. 10; e5299108853Research, Society and Development; Vol. 9 Núm. 10; e5299108853Research, Society and Development; v. 9 n. 10; e52991088532525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/8853/7916Copyright (c) 2020 Priscilla Régia de Andrade Calaça; Elaine Cristina da Silva; Felipe Pereira de Melo; Dayane da Silva Santos; Ana Beatriz Lins Aragão; Pablo Eugênio da Costa e Silva; Mércia Rodrigues Barros; Ana Lúcia Figueiredo Porto; Maria Taciana Cavalcanti Vieira Soareshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCalaça, Priscilla Régia de AndradeSilva, Elaine Cristina daMelo, Felipe Pereira deSantos, Dayane da SilvaAragão, Ana Beatriz Lins Silva, Pablo Eugênio da Costa eBarros, Mércia RodriguesPorto, Ana Lúcia FigueiredoSoares, Maria Taciana Cavalcanti Vieira2020-10-31T12:03:23Zoai:ojs.pkp.sfu.ca:article/8853Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:14.104420Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species Enterococcus faecium EF137V: una nueva fuente estratégica para el control de la salud humana y animal contra especies de Campylobacter Enterococcus faecium EF137V: uma nova fonte estratégica para o controle da saúde humana e animal contra espécies de Campylobacter |
title |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
spellingShingle |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species Calaça, Priscilla Régia de Andrade Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnologia. Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnología. Probiotics Enterococcus faecium Campylobacter jejuni Campylobacter coli Biothecnology. |
title_short |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
title_full |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
title_fullStr |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
title_full_unstemmed |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
title_sort |
Enterococcus faecium EF137V: a new strategic source for the control of human and animal health against Campylobacter species |
author |
Calaça, Priscilla Régia de Andrade |
author_facet |
Calaça, Priscilla Régia de Andrade Silva, Elaine Cristina da Melo, Felipe Pereira de Santos, Dayane da Silva Aragão, Ana Beatriz Lins Silva, Pablo Eugênio da Costa e Barros, Mércia Rodrigues Porto, Ana Lúcia Figueiredo Soares, Maria Taciana Cavalcanti Vieira |
author_role |
author |
author2 |
Silva, Elaine Cristina da Melo, Felipe Pereira de Santos, Dayane da Silva Aragão, Ana Beatriz Lins Silva, Pablo Eugênio da Costa e Barros, Mércia Rodrigues Porto, Ana Lúcia Figueiredo Soares, Maria Taciana Cavalcanti Vieira |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Calaça, Priscilla Régia de Andrade Silva, Elaine Cristina da Melo, Felipe Pereira de Santos, Dayane da Silva Aragão, Ana Beatriz Lins Silva, Pablo Eugênio da Costa e Barros, Mércia Rodrigues Porto, Ana Lúcia Figueiredo Soares, Maria Taciana Cavalcanti Vieira |
dc.subject.por.fl_str_mv |
Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnologia. Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnología. Probiotics Enterococcus faecium Campylobacter jejuni Campylobacter coli Biothecnology. |
topic |
Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnologia. Probióticos Enterococcus faecium Campylobacter jejuni Campylobacter coli Biotecnología. Probiotics Enterococcus faecium Campylobacter jejuni Campylobacter coli Biothecnology. |
description |
The probiotic is related to a food supplement, while the live biotherapeutic products - LBPs are considered biological medicines, both contain living microorganisms with active substances that benefit the host. Enterococcus faecium has many interesting and functional properties for human and animal health, including the antimicrobial capacity, which helps in food poisoning diseases such as Campylobacteriosis. Campylobacter jejuni and C. coli species have been described in this context. Therefore, due to the need to develop alternatives to ensure the safety of products consumed by the population, this work proposes a complementary strategy to reduce or eliminate Campylobacter through the use of Enterococcus faecium EF137V, isolated from artisanal “Coalho” cheese from Pernambuco-Brazil. The analyzes were performed in vitro. Given the adverse conditions, such as acid pH and the presence of bile salts, in which EF137V was exposed, it was found that the bacteria showed resistance to gastrointestinal conditions, adherence to epithelial cells, antimicrobial activity by its metabolic compounds against reference strains of C. jejuni and C. coli, as well as antagonistic activity, which suggests that both species will not be able to grow disorderly in the host's intestinal microbiota, thus being able to control these microorganisms in the bacterial community in broilers and preventing new infections in humans. It can be concluded that the EF137V is a promising PVB and probiotic, presenting great capacity for biotechnology applications. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-06 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/8853 10.33448/rsd-v9i10.8853 |
url |
https://rsdjournal.org/index.php/rsd/article/view/8853 |
identifier_str_mv |
10.33448/rsd-v9i10.8853 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/8853/7916 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 10; e5299108853 Research, Society and Development; Vol. 9 Núm. 10; e5299108853 Research, Society and Development; v. 9 n. 10; e5299108853 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052781145620480 |