Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26182 |
Resumo: | Cancer treatment results in considerable adverse effects, with oral mucositis being the most reported complication. This study aimed to compare the effect of three mouthwashes formulated from herbal medicines in the prevention and therapy of oral lesions caused by mucositis. Patients who were undergoing chemotherapy treatment at the Santa Terezinha de Joaçaba/SC University Hospital were used as a sample. After approaching the interviewees, a free and informed consent form was signed, followed by an interview to collect information related to the patient and his current cancer-related condition. Patients were divided into 03 groups with 11 participants, each group receiving one of the three solutions studied. The participants were then instructed to rinse their mouths with 10ml of the solution, 04 times a day for 05 days. After the application, information was collected through telephone calls, based on the Oral Mucositis and Daily Questionnaire. As for the pain reported by the patients, 22 (71%) answered "no pain" and 17 (55%) rated their pain, on a scale from 0 to 10, with a score of 1. Only 1 patient (3%) answered "a lot of pain", classifying it as a score of 9. Regarding the reported limitations, 22 (71%) had no limitations in eating and speaking. Only 1 (3%) reported difficulty speaking and "very limited" in drinking and eating. No patient reported disability. It was concluded that the herbal solutions used as a therapeutic form showed similar effectiveness. However, no patient developed mucositis during the period of mouthwash use, suggesting an effect also as a preventive factor. |
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Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind studyComparación entre el efecto de tres collarines en la terapéutica y prevención de la mucositis inducida por quimio – estudio doble ciegoComparação entre o efeito de três enxaguatorios bucais na terapêutica e prevenção da mucosite quimioinduzida – estudo duplo cegoEstomatiteMucositeDrogas FitoterápicasAntineoplásicosCamomilaCalendulaAloe vera.EstomatitisMucositisMedicamentos FitoterápicosAntineoplásicosManzanillaCalendulaAloe.StomatitisMucositisPhytotherapeutic DrugsAntineoplastic AgentsChamomileCalendulaAloe.Cancer treatment results in considerable adverse effects, with oral mucositis being the most reported complication. This study aimed to compare the effect of three mouthwashes formulated from herbal medicines in the prevention and therapy of oral lesions caused by mucositis. Patients who were undergoing chemotherapy treatment at the Santa Terezinha de Joaçaba/SC University Hospital were used as a sample. After approaching the interviewees, a free and informed consent form was signed, followed by an interview to collect information related to the patient and his current cancer-related condition. Patients were divided into 03 groups with 11 participants, each group receiving one of the three solutions studied. The participants were then instructed to rinse their mouths with 10ml of the solution, 04 times a day for 05 days. After the application, information was collected through telephone calls, based on the Oral Mucositis and Daily Questionnaire. As for the pain reported by the patients, 22 (71%) answered "no pain" and 17 (55%) rated their pain, on a scale from 0 to 10, with a score of 1. Only 1 patient (3%) answered "a lot of pain", classifying it as a score of 9. Regarding the reported limitations, 22 (71%) had no limitations in eating and speaking. Only 1 (3%) reported difficulty speaking and "very limited" in drinking and eating. No patient reported disability. It was concluded that the herbal solutions used as a therapeutic form showed similar effectiveness. However, no patient developed mucositis during the period of mouthwash use, suggesting an effect also as a preventive factor.Además de la morbilidad relacionada con el cáncer, su tratamiento produce efectos adversos considerables, siendo la mucositis oral la complicación más reportada. Este estudio tuvo como objetivo comparar el efecto de tres enjuagues bucales formulados a base de hierbas medicinales en la prevención y tratamiento de las lesiones bucales causadas por la mucositis. Se utilizaron como muestra pacientes que estaban en tratamiento de quimioterapia en el Hospital Universitario Santa Terezinha de Joaçaba/SC. Después del acercamiento a los entrevistados, se firmó un consentimiento libre e informado, seguido de una entrevista para recopilar información relacionada con el paciente y su condición actual relacionada con el cáncer. Los pacientes fueron divididos en 03 grupos con 11 participantes, cada grupo recibió una de las tres soluciones estudiadas. Luego, se instruyó a los participantes para que se enjuagaran la boca con 10 ml de la solución, 04 veces al día durante 05 días. Después de la aplicación, la información fue recolectada a través de llamadas telefónicas, con base en el Cuestionario de Mucositis Oral y Diario. En cuanto al dolor referido por los pacientes, 22 (71%) respondieron "sin dolor" y 17 (55%) calificaron su dolor, en una escala de 0 a 10, con una puntuación de 1. Solo 1 paciente (3%) respondió "mucho dolor", clasificándolo con un puntaje de 9. En cuanto a las limitaciones relatadas, 22 (71%) no tenían limitaciones para comer y hablar. Solo 1 (3%) refirió dificultad para hablar y "muy limitada" para beber y comer. Ningún paciente refirió discapacidad. Se concluyó que las soluciones herbales utilizadas como forma terapéutica mostraron una efectividad similar. Sin embargo, ningún paciente desarrolló mucositis durante el período de uso del enjuague bucal, lo que sugiere un efecto también como factor preventivo.Além da morbidade relacionada ao câncer, seu tratamento resulta em consideráveis efeitos adversos, sendo a mucosite oral a complicação mais relatada. Este estudo objetivou comparar o efeito de dois enxaguantes bucais formulados a partir de fitoterápicos e nistatina como solução controle, na prevenção e terapêutica da mucosite oral. Participaram do estudo pacientes que estavam realizando tratamento quimioterápico no Hospital Universitário Santa Terezinha de Joaçaba/SC. Após a abordagem dos entrevistados, coletou-se assinatura do termo de consentimento livre e esclarecido, seguida por uma entrevista para a coleta das informações relacionadas ao paciente e sua atual condição relacionada ao câncer. Os pacientes foram divididos em 03 grupos com 11 participantes, sendo que cada grupo recebeu uma das três soluções estudadas. Foram então orientados a realizarem bochechos com 10ml da solução, 04 vezes ao dia durante 05 dias. Após a aplicação, coletou-se informações baseando-se no questionário Oral Mucositis and Daily Questionnaire. Quanto a dor relatada, 71% responderam "sem dor" e 55% dos pacientes classificaram a dor com score 1, em uma escala de 0 a 10. Apenas 1 paciente (3%) respondeu "muita dor", classificando-a com score 9. Sobre as limitações relatadas, 71% não apresentaram limitações para comer e falar. Apenas 1 paciente (3%) relatou dificuldade para falar e "muito limitado" para beber e comer. Nenhum paciente relatou incapacidade. Não se observou diferença entre as soluções estudadas. Concluiu-se que os enxaguantes fitoterápicos utilizados como forma terapêutica demonstraram efetividade semelhante. Ainda, nenhum paciente desenvolveu mucosite durante a aplicação dos bochechos, sugerindo efeito também efeito preventivo.Research, Society and Development2022-02-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2618210.33448/rsd-v11i3.26182Research, Society and Development; Vol. 11 No. 3; e14311326182Research, Society and Development; Vol. 11 Núm. 3; e14311326182Research, Society and Development; v. 11 n. 3; e143113261822525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26182/24850Copyright (c) 2022 João Francisco Barbosa Cordeiro; Waleska Tychanowicz Kolodziejwski; Acir José Disrchnabel; Claudia Elisa Grasel; Soraia Almeida Watanabe Imanishi; Shaline Ferla Baptistella; Lea Maria Franceschi Dallanora; Grasieli de Oliveira Ramoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCordeiro, João Francisco Barbosa Kolodziejwski, Waleska TychanowiczDisrchnabel, Acir JoséGrasel, Claudia Elisa Imanishi, Soraia Almeida Watanabe Baptistella, Shaline Ferla Dallanora, Lea Maria Franceschi Ramos, Grasieli de Oliveira2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26182Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:17.187727Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study Comparación entre el efecto de tres collarines en la terapéutica y prevención de la mucositis inducida por quimio – estudio doble ciego Comparação entre o efeito de três enxaguatorios bucais na terapêutica e prevenção da mucosite quimioinduzida – estudo duplo cego |
title |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
spellingShingle |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study Cordeiro, João Francisco Barbosa Estomatite Mucosite Drogas Fitoterápicas Antineoplásicos Camomila Calendula Aloe vera. Estomatitis Mucositis Medicamentos Fitoterápicos Antineoplásicos Manzanilla Calendula Aloe. Stomatitis Mucositis Phytotherapeutic Drugs Antineoplastic Agents Chamomile Calendula Aloe. |
title_short |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
title_full |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
title_fullStr |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
title_full_unstemmed |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
title_sort |
Comparison between the effect of three mouthwrins on the therapeutic and prevention of chemo-induced mucositis – double blind study |
author |
Cordeiro, João Francisco Barbosa |
author_facet |
Cordeiro, João Francisco Barbosa Kolodziejwski, Waleska Tychanowicz Disrchnabel, Acir José Grasel, Claudia Elisa Imanishi, Soraia Almeida Watanabe Baptistella, Shaline Ferla Dallanora, Lea Maria Franceschi Ramos, Grasieli de Oliveira |
author_role |
author |
author2 |
Kolodziejwski, Waleska Tychanowicz Disrchnabel, Acir José Grasel, Claudia Elisa Imanishi, Soraia Almeida Watanabe Baptistella, Shaline Ferla Dallanora, Lea Maria Franceschi Ramos, Grasieli de Oliveira |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Cordeiro, João Francisco Barbosa Kolodziejwski, Waleska Tychanowicz Disrchnabel, Acir José Grasel, Claudia Elisa Imanishi, Soraia Almeida Watanabe Baptistella, Shaline Ferla Dallanora, Lea Maria Franceschi Ramos, Grasieli de Oliveira |
dc.subject.por.fl_str_mv |
Estomatite Mucosite Drogas Fitoterápicas Antineoplásicos Camomila Calendula Aloe vera. Estomatitis Mucositis Medicamentos Fitoterápicos Antineoplásicos Manzanilla Calendula Aloe. Stomatitis Mucositis Phytotherapeutic Drugs Antineoplastic Agents Chamomile Calendula Aloe. |
topic |
Estomatite Mucosite Drogas Fitoterápicas Antineoplásicos Camomila Calendula Aloe vera. Estomatitis Mucositis Medicamentos Fitoterápicos Antineoplásicos Manzanilla Calendula Aloe. Stomatitis Mucositis Phytotherapeutic Drugs Antineoplastic Agents Chamomile Calendula Aloe. |
description |
Cancer treatment results in considerable adverse effects, with oral mucositis being the most reported complication. This study aimed to compare the effect of three mouthwashes formulated from herbal medicines in the prevention and therapy of oral lesions caused by mucositis. Patients who were undergoing chemotherapy treatment at the Santa Terezinha de Joaçaba/SC University Hospital were used as a sample. After approaching the interviewees, a free and informed consent form was signed, followed by an interview to collect information related to the patient and his current cancer-related condition. Patients were divided into 03 groups with 11 participants, each group receiving one of the three solutions studied. The participants were then instructed to rinse their mouths with 10ml of the solution, 04 times a day for 05 days. After the application, information was collected through telephone calls, based on the Oral Mucositis and Daily Questionnaire. As for the pain reported by the patients, 22 (71%) answered "no pain" and 17 (55%) rated their pain, on a scale from 0 to 10, with a score of 1. Only 1 patient (3%) answered "a lot of pain", classifying it as a score of 9. Regarding the reported limitations, 22 (71%) had no limitations in eating and speaking. Only 1 (3%) reported difficulty speaking and "very limited" in drinking and eating. No patient reported disability. It was concluded that the herbal solutions used as a therapeutic form showed similar effectiveness. However, no patient developed mucositis during the period of mouthwash use, suggesting an effect also as a preventive factor. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26182 10.33448/rsd-v11i3.26182 |
url |
https://rsdjournal.org/index.php/rsd/article/view/26182 |
identifier_str_mv |
10.33448/rsd-v11i3.26182 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26182/24850 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 3; e14311326182 Research, Society and Development; Vol. 11 Núm. 3; e14311326182 Research, Society and Development; v. 11 n. 3; e14311326182 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052704580698112 |