Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/13588 |
Resumo: | Introduction: Sedatives are drugs used as therapeutic aid in patients under intensive care. Among the possible controversial outcomes for its use, cognitive changes are punctuated in the literature, with acute encephalopathy or delirium, being the most described. Objectives: To evaluate the association between the use of drugs with sedative action for the development of delirium and to characterize the functional profile of individuals with delirium. Material and Methods: Longitudinal study, carried out in a public hospital in the state network, from June 2019 to October (first half) of 2020, with individuals over 18 years old, admitted to intensive care units and infirmaries, for scales for assessing sedation, delirium and functionality (Richmond Agitation Sedation Scale - RASS, Confusion Assessment Method for the Intensive Care Unit - CAM-ICU and Status Score for the Intensive Care Unit - FSS, respectively), with verbalization and without admission via external transfer. Results: 104 patients with a mean age of 59.7 ± 15.3 years were included, 53.2% being male, with 49% being hypertensive and 79.8% denying smoking. There was not any statistical significance between sedative drugs for the onset of delirium. Most patients with delirium were in the FSS range between 0-15 in the intensive care unit setting and 16-25 in the infirmaries. Final considerations: There is no association between the use of drugs with sedative action and delirium. There was a change in the functional profile, with patients becoming moderate to maximum dependents in the intensive care units and minimize or independent dependents in the wards. |
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Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care unitsAcción de los fármacos sedantes para el desarrollo del delirio y perfil funcional de pacientes ingresados en unidades de cuidados intensivosAção de fármacos sedativos para o desenvolvimento de delirium e perfil funcional de pacientes internados em unidades de terapia intensivaDeliriumSedativosDisfunção CognitivaLimitação da mobilidade.DelirioSedantesDisfunción CognitivaLimitación de la movilidad.DeliriumSedativesCognitive DysfunctionMobility limitation.Introduction: Sedatives are drugs used as therapeutic aid in patients under intensive care. Among the possible controversial outcomes for its use, cognitive changes are punctuated in the literature, with acute encephalopathy or delirium, being the most described. Objectives: To evaluate the association between the use of drugs with sedative action for the development of delirium and to characterize the functional profile of individuals with delirium. Material and Methods: Longitudinal study, carried out in a public hospital in the state network, from June 2019 to October (first half) of 2020, with individuals over 18 years old, admitted to intensive care units and infirmaries, for scales for assessing sedation, delirium and functionality (Richmond Agitation Sedation Scale - RASS, Confusion Assessment Method for the Intensive Care Unit - CAM-ICU and Status Score for the Intensive Care Unit - FSS, respectively), with verbalization and without admission via external transfer. Results: 104 patients with a mean age of 59.7 ± 15.3 years were included, 53.2% being male, with 49% being hypertensive and 79.8% denying smoking. There was not any statistical significance between sedative drugs for the onset of delirium. Most patients with delirium were in the FSS range between 0-15 in the intensive care unit setting and 16-25 in the infirmaries. Final considerations: There is no association between the use of drugs with sedative action and delirium. There was a change in the functional profile, with patients becoming moderate to maximum dependents in the intensive care units and minimize or independent dependents in the wards.Introducción: Los sedantes son fármacos utilizados como ayudas terapéuticas en pacientes en cuidados intensivos. Entre los posibles desenlaces controvertidos para su uso, los cambios cognitivos se puntúan en la literatura, siendo la encefalopatía aguda o el delirio, los más reportados. Objetivos: Evaluar la asociación entre el uso de fármacos con acción sedante para el desarrollo del delirio y caracterizar el perfil funcional de los individuos con delirio. Material y Métodos: Estudio longitudinal, realizado en un hospital público de la red estatal, durante los meses de junio de 2019 a octubre (primer semestre) de 2020, con personas mayores de 18 años, ingresadas en unidades y salas de cuidados intensivos, mediante escalas. Por la evaluar sedación, delirio y funcionalidad (Richmond Agitation Sedation Scale - RASS, Confusion Assessment Method for the Intensive Care Unit - CAM-ICU y Status Score for the Intensive Care Unit - FSS, respectivamente), con capacidad de verbalización y sin ingreso por transferencia externo. Resultados: Se incluyeron 104 pacientes con una edad média de 59,7 ± 15,3 años, 53,2% varones, 49% hipertensos y 79,8% negaban fumar. No hubo significación estadística entre los fármacos sedantes para la aparición del delirio. La mayoría de los pacientes con delirio estaban en el rango de FSS entre 0-15 en el entorno intensivo y 16-25 en las salas. Consideraciones finales: No existe asociación entre el uso de fármacos con acción sedante y el delirio. Hubo un cambio en el perfil funcional, convirtiéndose los pacientes en dependientes moderados a máximos en las unidades de cuidados intensivos y dependientes mínimos o independientes en las salas.Introdução: Os sedativos são fármacos utilizados como auxiliares terapêuticos em pacientes sob cuidados intensivos. Dentre os possíveis desfechos controversos ao seu uso, as alterações cognitivas são pontuadas na literatura, com a encefalopatia aguda ou delirium, sendo a mais descrita. Objetivos: Avaliar a associação entre o uso de fármacos com ação sedativa para o desenvolvimento de delirium e caracterizar o perfil funcional dos indivíduos com delirium. Material e métodos: Estudo longitudinal, realizado em um hospital público da rede estadual, durante os meses de junho de 2019 a outubro (primeira quinzena) de 2020, com indivíduos acima de 18 anos, internados em unidades de terapia intensiva e enfermarias, por meio de escalas para avaliação de sedação, delirium e funcionalidade (Richmond Agitation Sedation Scale - RASS, Confusion Assessment Method for the Intensive Care Unit - CAM-ICU e Status Score for the Intensive Care Unit - FSS, respectivamente), com capacidade de verbalização e sem admissão via transferência externa. Resultados: Inclusos 104 pacientes com idade média de 59,7 ± 15,3 anos, sendo 53,2% do sexo masculino, com 49% sendo hipertensos e 79,8% negando tabagismo. Não houve significância estatística entre os fármacos sedativos para o desencadeamento de delirium. A maioria dos pacientes com delirium estavam no intervalo da FSS entre 0-15 no ambiente intensivo e 16-25 nas enfermarias. Considerações finais: Não há associação entre o uso de fármacos com ação sedativa e delirium. Houve alteração do perfil funcional, com os pacientes tornando-se dependentes moderados a máximos nas unidades intensivas e dependentes mínimos ou independentes nas enfermarias.Research, Society and Development2021-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1358810.33448/rsd-v10i3.13588Research, Society and Development; Vol. 10 No. 3; e45410313588Research, Society and Development; Vol. 10 Núm. 3; e45410313588Research, Society and Development; v. 10 n. 3; e454103135882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIengporhttps://rsdjournal.org/index.php/rsd/article/view/13588/12204https://rsdjournal.org/index.php/rsd/article/view/13588/12205Copyright (c) 2021 Anne Karine Menezes Santos Batista; Tais Santana Barbosa; Phydel Palmeira Carvalho; Natasha Cordeiro dos Santos; Victor Durier Cavalcanti de Almeida; Fernanda Warken Rosa Camelierhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBatista, Anne Karine Menezes Santos Barbosa, Tais Santana Carvalho, Phydel Palmeira Santos, Natasha Cordeiro dos Almeida, Victor Durier Cavalcanti de Camelier, Fernanda Warken Rosa 2021-03-28T12:03:35Zoai:ojs.pkp.sfu.ca:article/13588Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:34:53.685358Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units Acción de los fármacos sedantes para el desarrollo del delirio y perfil funcional de pacientes ingresados en unidades de cuidados intensivos Ação de fármacos sedativos para o desenvolvimento de delirium e perfil funcional de pacientes internados em unidades de terapia intensiva |
title |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
spellingShingle |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units Batista, Anne Karine Menezes Santos Delirium Sedativos Disfunção Cognitiva Limitação da mobilidade. Delirio Sedantes Disfunción Cognitiva Limitación de la movilidad. Delirium Sedatives Cognitive Dysfunction Mobility limitation. |
title_short |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
title_full |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
title_fullStr |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
title_full_unstemmed |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
title_sort |
Action of sedative drugs for the development of delirium and functional profile of patients admitted to intensive care units |
author |
Batista, Anne Karine Menezes Santos |
author_facet |
Batista, Anne Karine Menezes Santos Barbosa, Tais Santana Carvalho, Phydel Palmeira Santos, Natasha Cordeiro dos Almeida, Victor Durier Cavalcanti de Camelier, Fernanda Warken Rosa |
author_role |
author |
author2 |
Barbosa, Tais Santana Carvalho, Phydel Palmeira Santos, Natasha Cordeiro dos Almeida, Victor Durier Cavalcanti de Camelier, Fernanda Warken Rosa |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Batista, Anne Karine Menezes Santos Barbosa, Tais Santana Carvalho, Phydel Palmeira Santos, Natasha Cordeiro dos Almeida, Victor Durier Cavalcanti de Camelier, Fernanda Warken Rosa |
dc.subject.por.fl_str_mv |
Delirium Sedativos Disfunção Cognitiva Limitação da mobilidade. Delirio Sedantes Disfunción Cognitiva Limitación de la movilidad. Delirium Sedatives Cognitive Dysfunction Mobility limitation. |
topic |
Delirium Sedativos Disfunção Cognitiva Limitação da mobilidade. Delirio Sedantes Disfunción Cognitiva Limitación de la movilidad. Delirium Sedatives Cognitive Dysfunction Mobility limitation. |
description |
Introduction: Sedatives are drugs used as therapeutic aid in patients under intensive care. Among the possible controversial outcomes for its use, cognitive changes are punctuated in the literature, with acute encephalopathy or delirium, being the most described. Objectives: To evaluate the association between the use of drugs with sedative action for the development of delirium and to characterize the functional profile of individuals with delirium. Material and Methods: Longitudinal study, carried out in a public hospital in the state network, from June 2019 to October (first half) of 2020, with individuals over 18 years old, admitted to intensive care units and infirmaries, for scales for assessing sedation, delirium and functionality (Richmond Agitation Sedation Scale - RASS, Confusion Assessment Method for the Intensive Care Unit - CAM-ICU and Status Score for the Intensive Care Unit - FSS, respectively), with verbalization and without admission via external transfer. Results: 104 patients with a mean age of 59.7 ± 15.3 years were included, 53.2% being male, with 49% being hypertensive and 79.8% denying smoking. There was not any statistical significance between sedative drugs for the onset of delirium. Most patients with delirium were in the FSS range between 0-15 in the intensive care unit setting and 16-25 in the infirmaries. Final considerations: There is no association between the use of drugs with sedative action and delirium. There was a change in the functional profile, with patients becoming moderate to maximum dependents in the intensive care units and minimize or independent dependents in the wards. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13588 10.33448/rsd-v10i3.13588 |
url |
https://rsdjournal.org/index.php/rsd/article/view/13588 |
identifier_str_mv |
10.33448/rsd-v10i3.13588 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13588/12204 https://rsdjournal.org/index.php/rsd/article/view/13588/12205 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 3; e45410313588 Research, Society and Development; Vol. 10 Núm. 3; e45410313588 Research, Society and Development; v. 10 n. 3; e45410313588 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052673037434880 |