Off label use of antimalarials in covid-19 patients

Detalhes bibliográficos
Autor(a) principal: Oliveira, Erivan de Souza
Data de Publicação: 2020
Outros Autores: Matos, Marcela Feitosa, Cavalcante, Olga Samara Silva, Morais, Arlandia Cristina Lima Nobre de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/3517
Resumo: This study aimed to verify the level of scientific evidence on the off label use of chloroquine and hydroxychloroquine for the treatment of patients with covid-19 in scientific productions published in renowned international journals. It is an integrative literature review, of an exploratory nature, with a qualitative approach. To compose the corpus of final analysis, 5 articles were selected that met the eligibility criteria established for the study. Through the works highlighted in this article, it is possible to observe that the drugs under study have promising results against covid-19 and can help prevent the progression of the disease to a critical state. It was observed that there were adverse reactions considered mild in two patients being treated with hydroxychloroquine, but no side effects considered serious. Caution is recommended when using these drugs, as they can cause adverse effects.
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spelling Off label use of antimalarials in covid-19 patientsUso de antimaláricos fuera de la etiqueta en pacientes con covid 19Uso off label de antimaláricos em pacientes portadores de covid-19ChloroquineCoronavirusHydroxychloroquineTreatment.CloroquinaCoronavírusHidroxicloroquinaTratamento.CloroquinaCoronavirusHidroxicloroquinaTratamiento.This study aimed to verify the level of scientific evidence on the off label use of chloroquine and hydroxychloroquine for the treatment of patients with covid-19 in scientific productions published in renowned international journals. It is an integrative literature review, of an exploratory nature, with a qualitative approach. To compose the corpus of final analysis, 5 articles were selected that met the eligibility criteria established for the study. Through the works highlighted in this article, it is possible to observe that the drugs under study have promising results against covid-19 and can help prevent the progression of the disease to a critical state. It was observed that there were adverse reactions considered mild in two patients being treated with hydroxychloroquine, but no side effects considered serious. Caution is recommended when using these drugs, as they can cause adverse effects.Este trabajo tiene por objetivo verificar el nivel de evidencia científica sobre el uso fuera de etiqueta de cloroquina e hidroxicloroquina para el tratamiento de pacientes con covid-19 en producciones científicas publicadas en reconocidas revistas internacionales. Es una revisión de literatura integradora, de naturaleza exploratoria, con un enfoque cualitativo. Para componer el corpus de análisis final, se seleccionaron 5 artículos que cumplían con los criterios de elegibilidad establecidos para el estudio. A través de los trabajos destacados en este artículo, es posible observar que los medicamentos en estudio tienen resultados prometedores contra covid-19 y pueden ayudar a prevenir la progresión de la enfermedad a un estado crítico. Se observó que hubo reacciones adversas consideradas leves en dos pacientes tratados con hidroxicloroquina, pero ningún efecto secundario se consideró grave. Se recomienda precaución al usar estos medicamentos, ya que pueden causar efectos adversos.Este trabalho teve como objetivo verificar o nível de evidência científica sobre o uso off label da cloroquina e hidroxicloroquina para o tratamento dos pacientes com a covid-19 em produções científicas publicadas em revistas internacionais de renome. Trata-se de uma revisão integrativa da literatura, de caráter exploratório, com abordagem qualitativa. Para compor o corpus de análise final foram selecionados 5 artigos que atendiam aos critérios de elegibilidade estabelecidos para o estudo. Através dos trabalhos destacados nesse artigo é possível observar que os medicamentos em estudo possuem resultados promissores contra a covid-19 e podem ajudar a impedir a progressão da doença para um estado crítico. Foi observado que houve reações adversas consideradas leves em dois pacientes em tratamento com a hidroxicloroquina, mas nenhum efeito colateral considerado grave. É recomendado cautela na utilização desses medicamentos, uma vez que podem causar efeitos adversos.Research, Society and Development2020-04-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/351710.33448/rsd-v9i6.3517Research, Society and Development; Vol. 9 No. 6; e168963517Research, Society and Development; Vol. 9 Núm. 6; e168963517Research, Society and Development; v. 9 n. 6; e1689635172525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/3517/3896Copyright (c) 2020 Erivan de Souza Oliveira, Marcela Feitosa Matos, Olga Samara Silva Cavalcante, Arlandia Cristina Lima Nobre de Moraisinfo:eu-repo/semantics/openAccessOliveira, Erivan de SouzaMatos, Marcela FeitosaCavalcante, Olga Samara SilvaMorais, Arlandia Cristina Lima Nobre de2020-08-20T18:05:46Zoai:ojs.pkp.sfu.ca:article/3517Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:27:42.150755Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Off label use of antimalarials in covid-19 patients
Uso de antimaláricos fuera de la etiqueta en pacientes con covid 19
Uso off label de antimaláricos em pacientes portadores de covid-19
title Off label use of antimalarials in covid-19 patients
spellingShingle Off label use of antimalarials in covid-19 patients
Oliveira, Erivan de Souza
Chloroquine
Coronavirus
Hydroxychloroquine
Treatment.
Cloroquina
Coronavírus
Hidroxicloroquina
Tratamento.
Cloroquina
Coronavirus
Hidroxicloroquina
Tratamiento.
title_short Off label use of antimalarials in covid-19 patients
title_full Off label use of antimalarials in covid-19 patients
title_fullStr Off label use of antimalarials in covid-19 patients
title_full_unstemmed Off label use of antimalarials in covid-19 patients
title_sort Off label use of antimalarials in covid-19 patients
author Oliveira, Erivan de Souza
author_facet Oliveira, Erivan de Souza
Matos, Marcela Feitosa
Cavalcante, Olga Samara Silva
Morais, Arlandia Cristina Lima Nobre de
author_role author
author2 Matos, Marcela Feitosa
Cavalcante, Olga Samara Silva
Morais, Arlandia Cristina Lima Nobre de
author2_role author
author
author
dc.contributor.author.fl_str_mv Oliveira, Erivan de Souza
Matos, Marcela Feitosa
Cavalcante, Olga Samara Silva
Morais, Arlandia Cristina Lima Nobre de
dc.subject.por.fl_str_mv Chloroquine
Coronavirus
Hydroxychloroquine
Treatment.
Cloroquina
Coronavírus
Hidroxicloroquina
Tratamento.
Cloroquina
Coronavirus
Hidroxicloroquina
Tratamiento.
topic Chloroquine
Coronavirus
Hydroxychloroquine
Treatment.
Cloroquina
Coronavírus
Hidroxicloroquina
Tratamento.
Cloroquina
Coronavirus
Hidroxicloroquina
Tratamiento.
description This study aimed to verify the level of scientific evidence on the off label use of chloroquine and hydroxychloroquine for the treatment of patients with covid-19 in scientific productions published in renowned international journals. It is an integrative literature review, of an exploratory nature, with a qualitative approach. To compose the corpus of final analysis, 5 articles were selected that met the eligibility criteria established for the study. Through the works highlighted in this article, it is possible to observe that the drugs under study have promising results against covid-19 and can help prevent the progression of the disease to a critical state. It was observed that there were adverse reactions considered mild in two patients being treated with hydroxychloroquine, but no side effects considered serious. Caution is recommended when using these drugs, as they can cause adverse effects.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3517
10.33448/rsd-v9i6.3517
url https://rsdjournal.org/index.php/rsd/article/view/3517
identifier_str_mv 10.33448/rsd-v9i6.3517
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3517/3896
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 6; e168963517
Research, Society and Development; Vol. 9 Núm. 6; e168963517
Research, Society and Development; v. 9 n. 6; e168963517
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
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