Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face

Detalhes bibliográficos
Autor(a) principal: Huamani, Fábio Henrique Vaicemlionis Gochomoto
Data de Publicação: 2023
Outros Autores: Suguihara, Roberto Teruo, Muknicka, Daniella Pilon
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/44372
Resumo: Botulinum toxin, derived from the Clostridium botulinum bacterium, has a multifaceted history, initially recognized for causing foodborne intoxications and more recently standing out for its therapeutic applications. Its mechanism of action, inhibiting the release of acetylcholine at neuromuscular junctions, results in temporary muscle paralysis, widely used in aesthetics to smooth wrinkles and enhance facial contours. Additionally, botulinum toxin has shown efficacy as an adjuvant in the treatment of facial neuropathic pain, providing relief to patients with conditions such as trigeminal neuralgia. The literature narrative review aims to deepen the understanding of this therapeutic application, analyzing clinical studies and systematic reviews to assess its effectiveness, safety, and mechanisms of action. The objective is to explore and consolidate the available evidence, identifying gaps in current knowledge and providing insights to guide future research and clinical practices in this specific field.
id UNIFEI_abc9e3ffb356cb86baea63e24d779c35
oai_identifier_str oai:ojs.pkp.sfu.ca:article/44372
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the faceToxina botulínica como opción coadyuvante en el tratamiento del dolor neuropático en la caraToxina botulínica como opção adjuvante no tratamento de dor neuropática na faceFaceBotulinum toxins, type AFacial nerve diseases.CaraToxinas botulínicas tipo AEnfermedades del nervio facial.FaceToxinas botulínicas tipo ADoenças do nervo facial.Botulinum toxin, derived from the Clostridium botulinum bacterium, has a multifaceted history, initially recognized for causing foodborne intoxications and more recently standing out for its therapeutic applications. Its mechanism of action, inhibiting the release of acetylcholine at neuromuscular junctions, results in temporary muscle paralysis, widely used in aesthetics to smooth wrinkles and enhance facial contours. Additionally, botulinum toxin has shown efficacy as an adjuvant in the treatment of facial neuropathic pain, providing relief to patients with conditions such as trigeminal neuralgia. The literature narrative review aims to deepen the understanding of this therapeutic application, analyzing clinical studies and systematic reviews to assess its effectiveness, safety, and mechanisms of action. The objective is to explore and consolidate the available evidence, identifying gaps in current knowledge and providing insights to guide future research and clinical practices in this specific field.La toxina botulínica, derivada de la bacteria Clostridium botulinum, tiene una historia multifacética, inicialmente reconocida por causar intoxicaciones alimentarias y, más recientemente, destacándose por sus aplicaciones terapéuticas. Su mecanismo de acción, que inhibe la liberación de acetilcolina en las uniones neuromusculares, resulta en parálisis muscular temporal, siendo ampliamente utilizada en estética para suavizar arrugas y realzar los contornos faciales. Además, la toxina botulínica ha demostrado eficacia como coadyuvante en el tratamiento del dolor neuropático facial, brindando alivio a pacientes con condiciones como la neuralgia del trigémino. La revisión narrativa de la literatura tiene como objetivo profundizar en la comprensión de esta aplicación terapéutica, analizando estudios clínicos y revisiones sistemáticas para evaluar su eficacia, seguridad y mecanismos de acción. El objetivo es explorar y consolidar las evidencias disponibles, identificando lagunas en el conocimiento actual y proporcionando ideas para orientar futuras investigaciones y prácticas clínicas en este campo específico.A toxina botulínica, originada da bactéria Clostridium botulinum, tem uma história multifacetada, inicialmente reconhecida por causar intoxicações alimentares e, mais recentemente, destacando-se por suas aplicações terapêuticas. Seu mecanismo de ação, inibindo a liberação de acetilcolina nas junções neuromusculares, resulta na paralisia temporária dos músculos, sendo amplamente empregado na estética para suavizar rugas e realçar contornos faciais. Além disso, a toxina botulínica demonstrou eficácia como adjuvante no tratamento da dor neuropática facial, oferecendo alívio a pacientes com condições como a neuralgia do trigêmeo. A revisão narrativa da literatura visa aprofundar a compreensão dessa aplicação terapêutica, analisando estudos clínicos e revisões sistemáticas para avaliar sua eficácia, segurança e mecanismos de ação. O objetivo é explorar e consolidar as evidências disponíveis, identificando lacunas no conhecimento atual e fornecendo insights para orientar futuras pesquisas e práticas clínicas nesse campo específico.Research, Society and Development2023-12-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4437210.33448/rsd-v12i13.44372Research, Society and Development; Vol. 12 No. 13; e112121344372Research, Society and Development; Vol. 12 Núm. 13; e112121344372Research, Society and Development; v. 12 n. 13; e1121213443722525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/44372/35516Copyright (c) 2023 Fábio Henrique Vaicemlionis Gochomoto Huamani; Roberto Teruo Suguihara; Daniella Pilon Muknickahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessHuamani, Fábio Henrique Vaicemlionis Gochomoto Suguihara, Roberto Teruo Muknicka, Daniella Pilon 2023-12-11T09:52:06Zoai:ojs.pkp.sfu.ca:article/44372Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-12-11T09:52:06Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
Toxina botulínica como opción coadyuvante en el tratamiento del dolor neuropático en la cara
Toxina botulínica como opção adjuvante no tratamento de dor neuropática na face
title Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
spellingShingle Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
Huamani, Fábio Henrique Vaicemlionis Gochomoto
Face
Botulinum toxins, type A
Facial nerve diseases.
Cara
Toxinas botulínicas tipo A
Enfermedades del nervio facial.
Face
Toxinas botulínicas tipo A
Doenças do nervo facial.
title_short Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
title_full Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
title_fullStr Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
title_full_unstemmed Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
title_sort Botulinum toxin as an adjuvant option in the treatment of neuropathic pain in the face
author Huamani, Fábio Henrique Vaicemlionis Gochomoto
author_facet Huamani, Fábio Henrique Vaicemlionis Gochomoto
Suguihara, Roberto Teruo
Muknicka, Daniella Pilon
author_role author
author2 Suguihara, Roberto Teruo
Muknicka, Daniella Pilon
author2_role author
author
dc.contributor.author.fl_str_mv Huamani, Fábio Henrique Vaicemlionis Gochomoto
Suguihara, Roberto Teruo
Muknicka, Daniella Pilon
dc.subject.por.fl_str_mv Face
Botulinum toxins, type A
Facial nerve diseases.
Cara
Toxinas botulínicas tipo A
Enfermedades del nervio facial.
Face
Toxinas botulínicas tipo A
Doenças do nervo facial.
topic Face
Botulinum toxins, type A
Facial nerve diseases.
Cara
Toxinas botulínicas tipo A
Enfermedades del nervio facial.
Face
Toxinas botulínicas tipo A
Doenças do nervo facial.
description Botulinum toxin, derived from the Clostridium botulinum bacterium, has a multifaceted history, initially recognized for causing foodborne intoxications and more recently standing out for its therapeutic applications. Its mechanism of action, inhibiting the release of acetylcholine at neuromuscular junctions, results in temporary muscle paralysis, widely used in aesthetics to smooth wrinkles and enhance facial contours. Additionally, botulinum toxin has shown efficacy as an adjuvant in the treatment of facial neuropathic pain, providing relief to patients with conditions such as trigeminal neuralgia. The literature narrative review aims to deepen the understanding of this therapeutic application, analyzing clinical studies and systematic reviews to assess its effectiveness, safety, and mechanisms of action. The objective is to explore and consolidate the available evidence, identifying gaps in current knowledge and providing insights to guide future research and clinical practices in this specific field.
publishDate 2023
dc.date.none.fl_str_mv 2023-12-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44372
10.33448/rsd-v12i13.44372
url https://rsdjournal.org/index.php/rsd/article/view/44372
identifier_str_mv 10.33448/rsd-v12i13.44372
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44372/35516
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 13; e112121344372
Research, Society and Development; Vol. 12 Núm. 13; e112121344372
Research, Society and Development; v. 12 n. 13; e112121344372
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052635310718976

Registros relacionados