Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions
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Data de Publicação: | 2021 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/13087 |
Resumo: | This study outlined the profile of drug treatment for patients treated at a specialized service, evaluating aspects related to adherence, adverse reactions (ADR) and drug interactions (IM), as well as the pharmacological response. The research was carried out in a specialized service located in São Miguel do Guamá-Pará, from August to September 2020, including patients who were under treatment and over 18 years old. To assess the pharmacological response, clinical aspects were considered before and after treatment. In the case of adherence, the Morisky Scale was used, the RAM, the Naranjo Algorithm and the IM were searched in specialized sites. The subjects, after treatment, had new symptoms or symptoms prior to treatment, despite being treated with 2 or more medications. Some problems were detected in this study, such as: more than 50% of patients had low adherence, had ADR and had at least one serious drug interaction. These results suggest that drug treatment may present a potential risk to the patient, requiring pharmacotherapeutic follow-up aimed at problems diagnosis of drug related problems, as well as resolving them. |
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Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactionsTratamiento farmacológico de pacientes con esquizofrenia: adherencia, interacciones medicamentosas y reacciones adversasTratamento medicamentoso de portadores da esquizofrenia: adesão, interações medicamentosas e reações adversasEsquizofreniaAdesãoInterações medicamentosasReações adversas medicamentosas.EsquizofreniaAdherenciaInteracciones farmacológicasReacciones adversas a medicamentos. SchizophreniaAdherenceDrug interactionsAdverse drug reactions.This study outlined the profile of drug treatment for patients treated at a specialized service, evaluating aspects related to adherence, adverse reactions (ADR) and drug interactions (IM), as well as the pharmacological response. The research was carried out in a specialized service located in São Miguel do Guamá-Pará, from August to September 2020, including patients who were under treatment and over 18 years old. To assess the pharmacological response, clinical aspects were considered before and after treatment. In the case of adherence, the Morisky Scale was used, the RAM, the Naranjo Algorithm and the IM were searched in specialized sites. The subjects, after treatment, had new symptoms or symptoms prior to treatment, despite being treated with 2 or more medications. Some problems were detected in this study, such as: more than 50% of patients had low adherence, had ADR and had at least one serious drug interaction. These results suggest that drug treatment may present a potential risk to the patient, requiring pharmacotherapeutic follow-up aimed at problems diagnosis of drug related problems, as well as resolving them.Este estudio esbozó el perfil del tratamiento farmacológico de los pacientes atendidos en un servicio especializado, evaluando aspectos relacionados con la adherencia, reacciones adversas (RAM) e interacciones medicamentosas (MI), así como la respuesta farmacológica. La investigación se realizó en un servicio especializado ubicado en São Miguel do Guamá-Pará, de agosto a septiembre de 2020, incluyendo pacientes en tratamiento y mayores de 18 años. Para evaluar la respuesta farmacológica, se consideraron aspectos clínicos antes y después del tratamiento. En el caso de la adherencia se utilizó la Escala de Morisky, la RAM, el Algoritmo de Naranjo y la IM se buscaron en sitios especializados. Los sujetos, después del tratamiento, tenían nuevos síntomas o síntomas antes del tratamiento, a pesar de haber sido tratados con 2 o más medicamentos. En este estudio se detectaron algunos problemas, tales como: más del 50% de los pacientes tenían baja adherencia, tenían RAM y tenían al menos una interacción medicamentosa grave. Estos resultados sugieren que el tratamiento farmacológico puede presentar un riesgo potencial para el paciente, requiriendo un seguimiento farmacoterapéutico dirigido a diagnosticar problemas relacionados con las drogas, así como a resolverlos.Objetivo: Presente estudo traçou o perfil do tratamento medicamentoso dos pacientes atendidos em serviço especializado, avaliando os aspectos relacionados a adesão, reações adversas medicamentosas (RAM) e interações medicamentosas (IM), bem como a resposta farmacológica. Metodologia: A pesquisa foi realizada em serviço especializado localizado em São Miguel do Guamá-Pará, no período de agosto a setembro de 2020, sendo incluídos os pacientes que estavam em tratamento e com mais de 18 anos. Para avaliar a resposta farmacológica considerou-se aspectos clínicos antes e pós tratamento. No caso da adesão utilizou-se a Escala de Morisky, as RAM o Algoritmo de Naranjo e as IM foram pesquisadas em sítios especializados. Resultados: Os sujeitos, após o tratamento, apresentavam novos sintomas ou sintomas anterior ao tratamento, apesar de serem tratados com 2 ou mais medicamentos. Alguns problemas foram detectados neste estudo, tais como: mais de 50% dos pacientes tiveram baixa adesão, apresentavam RAM e tiveram, pelo menos, uma interação medicamentosa grave. Conclusão: Estes resultados sugerem que o tratamento medicamentoso pode apresentar um potencial risco ao paciente, sendo necessário um acompanhamento farmacoterapêutico que vise o diagnóstico dos problemas relacionados aos medicamentos, bem como, sua resolução.Research, Society and Development2021-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1308710.33448/rsd-v10i3.13087Research, Society and Development; Vol. 10 No. 3; e2010313087Research, Society and Development; Vol. 10 Núm. 3; e2010313087Research, Society and Development; v. 10 n. 3; e20103130872525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/13087/11679Copyright (c) 2021 Liliane Oliveira Cruz; Maria Fani Dolabelahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCruz, Liliane Oliveira Dolabela, Maria Fani 2021-03-28T12:03:35Zoai:ojs.pkp.sfu.ca:article/13087Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:34:30.808359Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions Tratamiento farmacológico de pacientes con esquizofrenia: adherencia, interacciones medicamentosas y reacciones adversas Tratamento medicamentoso de portadores da esquizofrenia: adesão, interações medicamentosas e reações adversas |
title |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
spellingShingle |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions Cruz, Liliane Oliveira Esquizofrenia Adesão Interações medicamentosas Reações adversas medicamentosas. Esquizofrenia Adherencia Interacciones farmacológicas Reacciones adversas a medicamentos. Schizophrenia Adherence Drug interactions Adverse drug reactions. |
title_short |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
title_full |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
title_fullStr |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
title_full_unstemmed |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
title_sort |
Drug treatment of patients with schizophrenia: adherence, drug interactions and adverse reactions |
author |
Cruz, Liliane Oliveira |
author_facet |
Cruz, Liliane Oliveira Dolabela, Maria Fani |
author_role |
author |
author2 |
Dolabela, Maria Fani |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Cruz, Liliane Oliveira Dolabela, Maria Fani |
dc.subject.por.fl_str_mv |
Esquizofrenia Adesão Interações medicamentosas Reações adversas medicamentosas. Esquizofrenia Adherencia Interacciones farmacológicas Reacciones adversas a medicamentos. Schizophrenia Adherence Drug interactions Adverse drug reactions. |
topic |
Esquizofrenia Adesão Interações medicamentosas Reações adversas medicamentosas. Esquizofrenia Adherencia Interacciones farmacológicas Reacciones adversas a medicamentos. Schizophrenia Adherence Drug interactions Adverse drug reactions. |
description |
This study outlined the profile of drug treatment for patients treated at a specialized service, evaluating aspects related to adherence, adverse reactions (ADR) and drug interactions (IM), as well as the pharmacological response. The research was carried out in a specialized service located in São Miguel do Guamá-Pará, from August to September 2020, including patients who were under treatment and over 18 years old. To assess the pharmacological response, clinical aspects were considered before and after treatment. In the case of adherence, the Morisky Scale was used, the RAM, the Naranjo Algorithm and the IM were searched in specialized sites. The subjects, after treatment, had new symptoms or symptoms prior to treatment, despite being treated with 2 or more medications. Some problems were detected in this study, such as: more than 50% of patients had low adherence, had ADR and had at least one serious drug interaction. These results suggest that drug treatment may present a potential risk to the patient, requiring pharmacotherapeutic follow-up aimed at problems diagnosis of drug related problems, as well as resolving them. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13087 10.33448/rsd-v10i3.13087 |
url |
https://rsdjournal.org/index.php/rsd/article/view/13087 |
identifier_str_mv |
10.33448/rsd-v10i3.13087 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13087/11679 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Liliane Oliveira Cruz; Maria Fani Dolabela https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Liliane Oliveira Cruz; Maria Fani Dolabela https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 3; e2010313087 Research, Society and Development; Vol. 10 Núm. 3; e2010313087 Research, Society and Development; v. 10 n. 3; e2010313087 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052832431472640 |