BUMETANIDE IN AUTISM SPECTRUM DISORDER
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Arquivos de Ciências da Saúde da UNIPAR (Online) |
Texto Completo: | https://revistas.unipar.br/index.php/saude/article/view/8774 |
Resumo: | Objectives: This study aimed to make a bibliographic update on the already published data on bumetanide, addressing the main information on its use in Autism Spectrum Disorder (ASD). Methods: This was an integrative narrative review in which the following databases were used: Web of Science, MEDLINE, ScienceDirect, and Scielo. The descriptors used were: Autism Spectrum Disorder, Autistic Disorder and Bumetanide. It was considered only articles published in English and French. Original articles, randomized clinical trials, case reports, and review articles were included. Results: The results show that the use of bumetanide alters regions of the brain linked to the positive development of language, improvement of visual contact, improvement in social interactions, among others. Studies are also concerned about the safety and efficacy of bumetanide in ASD since several adverse effects have been reported. The most frequent were hypokalemia, polyuria, and loss of appetite. Conclusion: Bumetanide has proven as effective in improving some important symptoms in ASD, especially linked to language and social interaction, however, studies with larger groups of patients and with longer treatment and observation time are needed to confirm the efficacy and clarify the safety profile in use for people with ASD. |
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Arquivos de Ciências da Saúde da UNIPAR (Online) |
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BUMETANIDE IN AUTISM SPECTRUM DISORDERObjectives: This study aimed to make a bibliographic update on the already published data on bumetanide, addressing the main information on its use in Autism Spectrum Disorder (ASD). Methods: This was an integrative narrative review in which the following databases were used: Web of Science, MEDLINE, ScienceDirect, and Scielo. The descriptors used were: Autism Spectrum Disorder, Autistic Disorder and Bumetanide. It was considered only articles published in English and French. Original articles, randomized clinical trials, case reports, and review articles were included. Results: The results show that the use of bumetanide alters regions of the brain linked to the positive development of language, improvement of visual contact, improvement in social interactions, among others. Studies are also concerned about the safety and efficacy of bumetanide in ASD since several adverse effects have been reported. The most frequent were hypokalemia, polyuria, and loss of appetite. Conclusion: Bumetanide has proven as effective in improving some important symptoms in ASD, especially linked to language and social interaction, however, studies with larger groups of patients and with longer treatment and observation time are needed to confirm the efficacy and clarify the safety profile in use for people with ASD.UNIPAR2022-09-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.unipar.br/index.php/saude/article/view/877410.25110/arqsaude.v26i3.2022.8774Arquivos de Ciências da Saúde da UNIPAR; v. 26 n. 3 (2022)1982-114X10.25110/arqsaude.v26i3.2022reponame:Arquivos de Ciências da Saúde da UNIPAR (Online)instname:Universidade Paranaense (UNIPAR)instacron:UNIPARporhttps://revistas.unipar.br/index.php/saude/article/view/8774/4294Copyright (c) 2022 Arquivos de Ciências da Saúde da UNIPARinfo:eu-repo/semantics/openAccessMoreira, Lucas da SilvaAragão, Gislei Frota2022-10-26T13:26:32Zoai:ojs2.revistas.unipar.br:article/8774Revistahttp://revistas.unipar.br/index.php/saudehttp://revistas.unipar.br/saude/oai||cedic@unipar.br|| arqsaude@unipar.br1982-114X1415-076Xopendoar:2022-10-26T13:26:32Arquivos de Ciências da Saúde da UNIPAR (Online) - Universidade Paranaense (UNIPAR)false |
dc.title.none.fl_str_mv |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
title |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
spellingShingle |
BUMETANIDE IN AUTISM SPECTRUM DISORDER Moreira, Lucas da Silva |
title_short |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
title_full |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
title_fullStr |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
title_full_unstemmed |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
title_sort |
BUMETANIDE IN AUTISM SPECTRUM DISORDER |
author |
Moreira, Lucas da Silva |
author_facet |
Moreira, Lucas da Silva Aragão, Gislei Frota |
author_role |
author |
author2 |
Aragão, Gislei Frota |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Moreira, Lucas da Silva Aragão, Gislei Frota |
description |
Objectives: This study aimed to make a bibliographic update on the already published data on bumetanide, addressing the main information on its use in Autism Spectrum Disorder (ASD). Methods: This was an integrative narrative review in which the following databases were used: Web of Science, MEDLINE, ScienceDirect, and Scielo. The descriptors used were: Autism Spectrum Disorder, Autistic Disorder and Bumetanide. It was considered only articles published in English and French. Original articles, randomized clinical trials, case reports, and review articles were included. Results: The results show that the use of bumetanide alters regions of the brain linked to the positive development of language, improvement of visual contact, improvement in social interactions, among others. Studies are also concerned about the safety and efficacy of bumetanide in ASD since several adverse effects have been reported. The most frequent were hypokalemia, polyuria, and loss of appetite. Conclusion: Bumetanide has proven as effective in improving some important symptoms in ASD, especially linked to language and social interaction, however, studies with larger groups of patients and with longer treatment and observation time are needed to confirm the efficacy and clarify the safety profile in use for people with ASD. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.unipar.br/index.php/saude/article/view/8774 10.25110/arqsaude.v26i3.2022.8774 |
url |
https://revistas.unipar.br/index.php/saude/article/view/8774 |
identifier_str_mv |
10.25110/arqsaude.v26i3.2022.8774 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.unipar.br/index.php/saude/article/view/8774/4294 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Arquivos de Ciências da Saúde da UNIPAR info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Arquivos de Ciências da Saúde da UNIPAR |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UNIPAR |
publisher.none.fl_str_mv |
UNIPAR |
dc.source.none.fl_str_mv |
Arquivos de Ciências da Saúde da UNIPAR; v. 26 n. 3 (2022) 1982-114X 10.25110/arqsaude.v26i3.2022 reponame:Arquivos de Ciências da Saúde da UNIPAR (Online) instname:Universidade Paranaense (UNIPAR) instacron:UNIPAR |
instname_str |
Universidade Paranaense (UNIPAR) |
instacron_str |
UNIPAR |
institution |
UNIPAR |
reponame_str |
Arquivos de Ciências da Saúde da UNIPAR (Online) |
collection |
Arquivos de Ciências da Saúde da UNIPAR (Online) |
repository.name.fl_str_mv |
Arquivos de Ciências da Saúde da UNIPAR (Online) - Universidade Paranaense (UNIPAR) |
repository.mail.fl_str_mv |
||cedic@unipar.br|| arqsaude@unipar.br |
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1800218855463714816 |