Tamoxifen treatment adherence assessment by women with breast cancer
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Revista de Epidemiologia e Controle de Infecção |
Texto Completo: | https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314 |
Resumo: | Justification and objectives: oral antineoplastic therapy has advantages compared to other therapies for the treatment of cancer, as it is administered at home, in a simple and fast way. However, this therapy increases patients’ responsibility for their treatment, and compliance is critical to its effectiveness. Few studies are evident regarding pharmacotherapeutic follow-up in oral antineoplastic therapy. In this context, this study seeks to assess adherence to tamoxifen treatment in women with breast cancer, before and after pharmacotherapeutic follow-up. Methods: this is a randomized, quantitative clinical study. Data collection was carried out for six months. Random randomization was divided into a control group and a follow-up group, with the follow-up subdivided into before and after follow-up. The follow-up group received individual pharmaceutical interventions monthly. Adherence was assessed by The Brief Medication Questionnaire, Brazilian version and drug-related problems as to necessity, effectiveness, and safety. Results: after pharmaceutical follow-p, a difference was observed between the follow-up group and the control group regarding physical activity (p=0.043), treatment adherence (p=0.006), reduction of side effects (p=0.003) and associated diseases (p=0.002). The most frequent drug-related problems were safety and adherence, for which 54 pharmaceutical interventions were performed. The side effects described by patients mainly affected the genital system and gastrointestinal tract. Conclusion: it was evident that pharmacotherapeutic follow-up effectively contributed to adherence to treatment with tamoxifen and the pharmaceutical interventions performed contributed to prevention and reduction of drug-related problems. |
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Revista de Epidemiologia e Controle de Infecção |
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Tamoxifen treatment adherence assessment by women with breast cancerAdesão à medicação. Antineoplásicos hormonais. Atenção Farmacêutica. Neoplasias de Mama. Oncologia.Justification and objectives: oral antineoplastic therapy has advantages compared to other therapies for the treatment of cancer, as it is administered at home, in a simple and fast way. However, this therapy increases patients’ responsibility for their treatment, and compliance is critical to its effectiveness. Few studies are evident regarding pharmacotherapeutic follow-up in oral antineoplastic therapy. In this context, this study seeks to assess adherence to tamoxifen treatment in women with breast cancer, before and after pharmacotherapeutic follow-up. Methods: this is a randomized, quantitative clinical study. Data collection was carried out for six months. Random randomization was divided into a control group and a follow-up group, with the follow-up subdivided into before and after follow-up. The follow-up group received individual pharmaceutical interventions monthly. Adherence was assessed by The Brief Medication Questionnaire, Brazilian version and drug-related problems as to necessity, effectiveness, and safety. Results: after pharmaceutical follow-p, a difference was observed between the follow-up group and the control group regarding physical activity (p=0.043), treatment adherence (p=0.006), reduction of side effects (p=0.003) and associated diseases (p=0.002). The most frequent drug-related problems were safety and adherence, for which 54 pharmaceutical interventions were performed. The side effects described by patients mainly affected the genital system and gastrointestinal tract. Conclusion: it was evident that pharmacotherapeutic follow-up effectively contributed to adherence to treatment with tamoxifen and the pharmaceutical interventions performed contributed to prevention and reduction of drug-related problems.Unisc2020-01-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/1331410.17058/jeic.v10i1.13314Revista de Epidemiologia e Controle de Infecção; Vol. 10 No. 1 (2020)Revista de Epidemiologia e Controle de Infecção; v. 10 n. 1 (2020)2238-3360reponame:Revista de Epidemiologia e Controle de Infecçãoinstname:Universidade de Santa Cruz do Sul (UNISC)instacron:UNISCengporhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/13314/9572https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314/8794Copyright (c) 2020 Caroline Oliveira Rangel, Christiane de Fátima Colet, Vanessa Adelina Casali Bandeira, Gabriela Tassotti Gelatti, Rodrigo Fernando dos Santos Salazar, Roberta Cattaneo Horninfo:eu-repo/semantics/openAccessRangel, Caroline OliveiraColet, Christiane de FátimaBandeira, Vanessa Adelina CasaliGelatti, Gabriela TassottiSalazar, Rodrigo Fernando dos SantosHorn, Roberta Cattaneo2022-08-08T13:00:00Zoai:ojs.online.unisc.br:article/13314Revistahttps://online.unisc.br/seer/index.php/epidemiologia/indexONGhttp://online.unisc.br/seer/index.php/epidemiologia/oai||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com2238-33602238-3360opendoar:2022-08-08T13:00Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC)false |
dc.title.none.fl_str_mv |
Tamoxifen treatment adherence assessment by women with breast cancer |
title |
Tamoxifen treatment adherence assessment by women with breast cancer |
spellingShingle |
Tamoxifen treatment adherence assessment by women with breast cancer Rangel, Caroline Oliveira Adesão à medicação. Antineoplásicos hormonais. Atenção Farmacêutica. Neoplasias de Mama. Oncologia. |
title_short |
Tamoxifen treatment adherence assessment by women with breast cancer |
title_full |
Tamoxifen treatment adherence assessment by women with breast cancer |
title_fullStr |
Tamoxifen treatment adherence assessment by women with breast cancer |
title_full_unstemmed |
Tamoxifen treatment adherence assessment by women with breast cancer |
title_sort |
Tamoxifen treatment adherence assessment by women with breast cancer |
author |
Rangel, Caroline Oliveira |
author_facet |
Rangel, Caroline Oliveira Colet, Christiane de Fátima Bandeira, Vanessa Adelina Casali Gelatti, Gabriela Tassotti Salazar, Rodrigo Fernando dos Santos Horn, Roberta Cattaneo |
author_role |
author |
author2 |
Colet, Christiane de Fátima Bandeira, Vanessa Adelina Casali Gelatti, Gabriela Tassotti Salazar, Rodrigo Fernando dos Santos Horn, Roberta Cattaneo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Rangel, Caroline Oliveira Colet, Christiane de Fátima Bandeira, Vanessa Adelina Casali Gelatti, Gabriela Tassotti Salazar, Rodrigo Fernando dos Santos Horn, Roberta Cattaneo |
dc.subject.por.fl_str_mv |
Adesão à medicação. Antineoplásicos hormonais. Atenção Farmacêutica. Neoplasias de Mama. Oncologia. |
topic |
Adesão à medicação. Antineoplásicos hormonais. Atenção Farmacêutica. Neoplasias de Mama. Oncologia. |
description |
Justification and objectives: oral antineoplastic therapy has advantages compared to other therapies for the treatment of cancer, as it is administered at home, in a simple and fast way. However, this therapy increases patients’ responsibility for their treatment, and compliance is critical to its effectiveness. Few studies are evident regarding pharmacotherapeutic follow-up in oral antineoplastic therapy. In this context, this study seeks to assess adherence to tamoxifen treatment in women with breast cancer, before and after pharmacotherapeutic follow-up. Methods: this is a randomized, quantitative clinical study. Data collection was carried out for six months. Random randomization was divided into a control group and a follow-up group, with the follow-up subdivided into before and after follow-up. The follow-up group received individual pharmaceutical interventions monthly. Adherence was assessed by The Brief Medication Questionnaire, Brazilian version and drug-related problems as to necessity, effectiveness, and safety. Results: after pharmaceutical follow-p, a difference was observed between the follow-up group and the control group regarding physical activity (p=0.043), treatment adherence (p=0.006), reduction of side effects (p=0.003) and associated diseases (p=0.002). The most frequent drug-related problems were safety and adherence, for which 54 pharmaceutical interventions were performed. The side effects described by patients mainly affected the genital system and gastrointestinal tract. Conclusion: it was evident that pharmacotherapeutic follow-up effectively contributed to adherence to treatment with tamoxifen and the pharmaceutical interventions performed contributed to prevention and reduction of drug-related problems. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314 10.17058/jeic.v10i1.13314 |
url |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314 |
identifier_str_mv |
10.17058/jeic.v10i1.13314 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314/9572 https://online.unisc.br/seer/index.php/epidemiologia/article/view/13314/8794 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Unisc |
publisher.none.fl_str_mv |
Unisc |
dc.source.none.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção; Vol. 10 No. 1 (2020) Revista de Epidemiologia e Controle de Infecção; v. 10 n. 1 (2020) 2238-3360 reponame:Revista de Epidemiologia e Controle de Infecção instname:Universidade de Santa Cruz do Sul (UNISC) instacron:UNISC |
instname_str |
Universidade de Santa Cruz do Sul (UNISC) |
instacron_str |
UNISC |
institution |
UNISC |
reponame_str |
Revista de Epidemiologia e Controle de Infecção |
collection |
Revista de Epidemiologia e Controle de Infecção |
repository.name.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC) |
repository.mail.fl_str_mv |
||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com |
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1800218811364802560 |