Ampolas de Vidro: Riscos e Benefícios
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/S0034-7094(11)70059-9 http://hdl.handle.net/11449/72511 |
Resumo: | Background and objectives: Glass ampoules have been widely used in packaging injection drugs. Glass has important characteristics that allow it to be widely used in fabrication of recipients for drugs and other sterile substances. However, contamination of solutions with glass microparticles on breaking open glass ampoules, the presence of metals, percutaneous injury, and biological contamination justify the need of educational materials to orient the manipulation of ampoules. Contents: Glass microparticles generated in the snap-opening of ampoules, as well as metals that contaminate their contents can be aspirated and injected through several routes. Exogenous contaminations by glass and metals can reach several sites in the organism. They trigger organic reactions that may give rise to injuries. Opening ampoules can expose professionals to the risk of percutaneous injuries. These lesions increase the biological risk as they are the gateway for viruses and bacteria. Ampoules opening systems (VIBRAC and OPC) have been developed to reduce the incidence of such accidents. Alternative materials to glass may represent an interesting strategy to increase safety. The use of prefilled syringes may represent an evolution regarding safety. Conclusions: Team training and information provided by the pharmaceutical industry on the use of ampoules are fundamental in the prophylaxis of accidents and contaminations. The search for safer materials to replace glass is also important. © 2011 Elsevier Editora Ltda. |
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Ampolas de Vidro: Riscos e BenefíciosGlass Ampoules: Risks and BenefitsAnesthesiologyDisposable equipmentEducation, medical, continuingGlassSafety managementglassaccidentampoulecontaminationdrug packagingriskDrug ContaminationDrug PackagingHealth PersonnelOccupational InjuriesRisk FactorsRisk ManagementBackground and objectives: Glass ampoules have been widely used in packaging injection drugs. Glass has important characteristics that allow it to be widely used in fabrication of recipients for drugs and other sterile substances. However, contamination of solutions with glass microparticles on breaking open glass ampoules, the presence of metals, percutaneous injury, and biological contamination justify the need of educational materials to orient the manipulation of ampoules. Contents: Glass microparticles generated in the snap-opening of ampoules, as well as metals that contaminate their contents can be aspirated and injected through several routes. Exogenous contaminations by glass and metals can reach several sites in the organism. They trigger organic reactions that may give rise to injuries. Opening ampoules can expose professionals to the risk of percutaneous injuries. These lesions increase the biological risk as they are the gateway for viruses and bacteria. Ampoules opening systems (VIBRAC and OPC) have been developed to reduce the incidence of such accidents. Alternative materials to glass may represent an interesting strategy to increase safety. The use of prefilled syringes may represent an evolution regarding safety. Conclusions: Team training and information provided by the pharmaceutical industry on the use of ampoules are fundamental in the prophylaxis of accidents and contaminations. The search for safer materials to replace glass is also important. © 2011 Elsevier Editora Ltda.UNESPSociedade de Anestesiologia do Espírito Santo - SAES CET Integrado HUCAM/HAFPES Physician of Serviço de Anestesiologia do HUCAM - UFESUniversidade de São Paulo (USP) Physician of Serviço de Anestesiologia do HUCAM - UFESCET Integrado HUCAM/HAFPESDepartamento de Clínica Cirúrgica da UFES CET Integrado HUCAM/HAFPESUNESPUniversidade Estadual Paulista (Unesp)Universidade Federal do Espírito Santo (UFES)Universidade de São Paulo (USP)CET Integrado HUCAM/HAFPESCarraretto, Antônio Roberto [UNESP]Curi, Erick Freitasde Almeida, Carlos Eduardo DavidAbatti, Roberta Eleni Monteiro2014-05-27T11:25:55Z2014-05-27T11:25:55Z2011-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article513-521application/pdfhttp://dx.doi.org/10.1016/S0034-7094(11)70059-9Revista Brasileira de Anestesiologia, v. 61, n. 4, p. 513-521, 2011.0034-70941806-907Xhttp://hdl.handle.net/11449/7251110.1016/S0034-7094(11)70059-92-s2.0-800525164612-s2.0-80052516461.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporRevista Brasileira de Anestesiologia0.8500,320info:eu-repo/semantics/openAccess2024-01-25T06:34:29Zoai:repositorio.unesp.br:11449/72511Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:58:05.241387Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Ampolas de Vidro: Riscos e Benefícios Glass Ampoules: Risks and Benefits |
title |
Ampolas de Vidro: Riscos e Benefícios |
spellingShingle |
Ampolas de Vidro: Riscos e Benefícios Carraretto, Antônio Roberto [UNESP] Anesthesiology Disposable equipment Education, medical, continuing Glass Safety management glass accident ampoule contamination drug packaging risk Drug Contamination Drug Packaging Health Personnel Occupational Injuries Risk Factors Risk Management |
title_short |
Ampolas de Vidro: Riscos e Benefícios |
title_full |
Ampolas de Vidro: Riscos e Benefícios |
title_fullStr |
Ampolas de Vidro: Riscos e Benefícios |
title_full_unstemmed |
Ampolas de Vidro: Riscos e Benefícios |
title_sort |
Ampolas de Vidro: Riscos e Benefícios |
author |
Carraretto, Antônio Roberto [UNESP] |
author_facet |
Carraretto, Antônio Roberto [UNESP] Curi, Erick Freitas de Almeida, Carlos Eduardo David Abatti, Roberta Eleni Monteiro |
author_role |
author |
author2 |
Curi, Erick Freitas de Almeida, Carlos Eduardo David Abatti, Roberta Eleni Monteiro |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Espírito Santo (UFES) Universidade de São Paulo (USP) CET Integrado HUCAM/HAFPES |
dc.contributor.author.fl_str_mv |
Carraretto, Antônio Roberto [UNESP] Curi, Erick Freitas de Almeida, Carlos Eduardo David Abatti, Roberta Eleni Monteiro |
dc.subject.por.fl_str_mv |
Anesthesiology Disposable equipment Education, medical, continuing Glass Safety management glass accident ampoule contamination drug packaging risk Drug Contamination Drug Packaging Health Personnel Occupational Injuries Risk Factors Risk Management |
topic |
Anesthesiology Disposable equipment Education, medical, continuing Glass Safety management glass accident ampoule contamination drug packaging risk Drug Contamination Drug Packaging Health Personnel Occupational Injuries Risk Factors Risk Management |
description |
Background and objectives: Glass ampoules have been widely used in packaging injection drugs. Glass has important characteristics that allow it to be widely used in fabrication of recipients for drugs and other sterile substances. However, contamination of solutions with glass microparticles on breaking open glass ampoules, the presence of metals, percutaneous injury, and biological contamination justify the need of educational materials to orient the manipulation of ampoules. Contents: Glass microparticles generated in the snap-opening of ampoules, as well as metals that contaminate their contents can be aspirated and injected through several routes. Exogenous contaminations by glass and metals can reach several sites in the organism. They trigger organic reactions that may give rise to injuries. Opening ampoules can expose professionals to the risk of percutaneous injuries. These lesions increase the biological risk as they are the gateway for viruses and bacteria. Ampoules opening systems (VIBRAC and OPC) have been developed to reduce the incidence of such accidents. Alternative materials to glass may represent an interesting strategy to increase safety. The use of prefilled syringes may represent an evolution regarding safety. Conclusions: Team training and information provided by the pharmaceutical industry on the use of ampoules are fundamental in the prophylaxis of accidents and contaminations. The search for safer materials to replace glass is also important. © 2011 Elsevier Editora Ltda. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-07-01 2014-05-27T11:25:55Z 2014-05-27T11:25:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/S0034-7094(11)70059-9 Revista Brasileira de Anestesiologia, v. 61, n. 4, p. 513-521, 2011. 0034-7094 1806-907X http://hdl.handle.net/11449/72511 10.1016/S0034-7094(11)70059-9 2-s2.0-80052516461 2-s2.0-80052516461.pdf |
url |
http://dx.doi.org/10.1016/S0034-7094(11)70059-9 http://hdl.handle.net/11449/72511 |
identifier_str_mv |
Revista Brasileira de Anestesiologia, v. 61, n. 4, p. 513-521, 2011. 0034-7094 1806-907X 10.1016/S0034-7094(11)70059-9 2-s2.0-80052516461 2-s2.0-80052516461.pdf |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
Revista Brasileira de Anestesiologia 0.850 0,320 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
513-521 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129567917867008 |