Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.joms.2011.01.028 http://hdl.handle.net/11449/226394 |
Resumo: | Purpose: The aim of this study was to evaluate the influence of estrogen deficiency on bone around osseointegrated dental implants in a rat jaw model. Materials and Methods: This study used 16 female rats that had the first molars bilaterally extracted and were allowed to heal for 30 days before implant placement. Sixty days after implant placement, the animals were randomly subjected to sham surgery or ovariectomy (OVX). The animals were euthanized 90 days after OVX. Bone-to-implant contact, bone area fraction occupancy between implant threads, mineral density, turnover markers, and cells positive for tartrate-resistant acid phosphatase were assessed for the 2 groups. Results: The results showed that OVX group presented a decrease of systemic bone density, alterations in bone turnover markers, and an increase of cells positive for tartrate-resistant acid phosphatase compared with the sham-surgery group. However, no difference relative to bone-to-implant contact and bone area fraction occupancy was observed between groups. Conclusions: The findings of this study demonstrate that estrogen deficiency may not be considered a risk factor for osseointegrated implant failure in jaw bone. © 2011 American Association of Oral and Maxillofacial Surgeons. |
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Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw modelPurpose: The aim of this study was to evaluate the influence of estrogen deficiency on bone around osseointegrated dental implants in a rat jaw model. Materials and Methods: This study used 16 female rats that had the first molars bilaterally extracted and were allowed to heal for 30 days before implant placement. Sixty days after implant placement, the animals were randomly subjected to sham surgery or ovariectomy (OVX). The animals were euthanized 90 days after OVX. Bone-to-implant contact, bone area fraction occupancy between implant threads, mineral density, turnover markers, and cells positive for tartrate-resistant acid phosphatase were assessed for the 2 groups. Results: The results showed that OVX group presented a decrease of systemic bone density, alterations in bone turnover markers, and an increase of cells positive for tartrate-resistant acid phosphatase compared with the sham-surgery group. However, no difference relative to bone-to-implant contact and bone area fraction occupancy was observed between groups. Conclusions: The findings of this study demonstrate that estrogen deficiency may not be considered a risk factor for osseointegrated implant failure in jaw bone. © 2011 American Association of Oral and Maxillofacial Surgeons.Department of Oral Diagnosis and Surgery Araraquara Dental School UNESP-Univ. Estadual Paulista, Araraquara, São PauloDepartment of Periodontology and Implant Dentistry New York University College of Dentistry, New York, NYInstituto de Pesquisa e Ensino Em Saúde, Uberlandia, MGBone Metabolism Laboratory of Rheumatology Division Faculdade de Medicina Universidade de São Paulo, São Paulo, São PauloDepartment of Immunology Forsyth Institute, Boston, MADepartment of Oral Diagnosis and Surgery Araraquara Dental School UNESP-Univ. Estadual Paulista, Araraquara, São PauloUniversidade Estadual Paulista (UNESP)College of DentistryInstituto de Pesquisa e Ensino Em SaúdeUniversidade de São Paulo (USP)Forsyth InstituteGiro, Gabriela [UNESP]Coelho, Paulo G.Sales-Pessoa, RobertoRodrigues Pereira, Rosa MariaKawai, ToshihisaPerez Orrico, Silvana Regina [UNESP]2022-04-28T22:48:46Z2022-04-28T22:48:46Z2011-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1911-1918http://dx.doi.org/10.1016/j.joms.2011.01.028Journal of Oral and Maxillofacial Surgery, v. 69, n. 7, p. 1911-1918, 2011.0278-23911531-5053http://hdl.handle.net/11449/22639410.1016/j.joms.2011.01.0282-s2.0-79959377191Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Oral and Maxillofacial Surgeryinfo:eu-repo/semantics/openAccess2022-04-28T22:48:46Zoai:repositorio.unesp.br:11449/226394Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:18:27.384962Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
title |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
spellingShingle |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model Giro, Gabriela [UNESP] |
title_short |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
title_full |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
title_fullStr |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
title_full_unstemmed |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
title_sort |
Influence of estrogen deficiency on bone around osseointegrated dental implants: An experimental study in the rat jaw model |
author |
Giro, Gabriela [UNESP] |
author_facet |
Giro, Gabriela [UNESP] Coelho, Paulo G. Sales-Pessoa, Roberto Rodrigues Pereira, Rosa Maria Kawai, Toshihisa Perez Orrico, Silvana Regina [UNESP] |
author_role |
author |
author2 |
Coelho, Paulo G. Sales-Pessoa, Roberto Rodrigues Pereira, Rosa Maria Kawai, Toshihisa Perez Orrico, Silvana Regina [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) College of Dentistry Instituto de Pesquisa e Ensino Em Saúde Universidade de São Paulo (USP) Forsyth Institute |
dc.contributor.author.fl_str_mv |
Giro, Gabriela [UNESP] Coelho, Paulo G. Sales-Pessoa, Roberto Rodrigues Pereira, Rosa Maria Kawai, Toshihisa Perez Orrico, Silvana Regina [UNESP] |
description |
Purpose: The aim of this study was to evaluate the influence of estrogen deficiency on bone around osseointegrated dental implants in a rat jaw model. Materials and Methods: This study used 16 female rats that had the first molars bilaterally extracted and were allowed to heal for 30 days before implant placement. Sixty days after implant placement, the animals were randomly subjected to sham surgery or ovariectomy (OVX). The animals were euthanized 90 days after OVX. Bone-to-implant contact, bone area fraction occupancy between implant threads, mineral density, turnover markers, and cells positive for tartrate-resistant acid phosphatase were assessed for the 2 groups. Results: The results showed that OVX group presented a decrease of systemic bone density, alterations in bone turnover markers, and an increase of cells positive for tartrate-resistant acid phosphatase compared with the sham-surgery group. However, no difference relative to bone-to-implant contact and bone area fraction occupancy was observed between groups. Conclusions: The findings of this study demonstrate that estrogen deficiency may not be considered a risk factor for osseointegrated implant failure in jaw bone. © 2011 American Association of Oral and Maxillofacial Surgeons. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-07-01 2022-04-28T22:48:46Z 2022-04-28T22:48:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.joms.2011.01.028 Journal of Oral and Maxillofacial Surgery, v. 69, n. 7, p. 1911-1918, 2011. 0278-2391 1531-5053 http://hdl.handle.net/11449/226394 10.1016/j.joms.2011.01.028 2-s2.0-79959377191 |
url |
http://dx.doi.org/10.1016/j.joms.2011.01.028 http://hdl.handle.net/11449/226394 |
identifier_str_mv |
Journal of Oral and Maxillofacial Surgery, v. 69, n. 7, p. 1911-1918, 2011. 0278-2391 1531-5053 10.1016/j.joms.2011.01.028 2-s2.0-79959377191 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Oral and Maxillofacial Surgery |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1911-1918 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129050208632832 |