Pemphigus vulgaris in adolescence: a case report

Detalhes bibliográficos
Autor(a) principal: Ferreira, Jean Paulo Rodolfo [UNESP]
Data de Publicação: 2013
Outros Autores: Araújo, Paula Caetano [UNESP], Saliba, Marcos Tadeu Adas, Consolaro, Renata Bianco [UNESP], Garbin, Cléa Adas Saliba [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4067/S0718-381X2013000200009
http://hdl.handle.net/11449/133402
Resumo: Pemphigus vulgaris is an autoimmune disease, normally associated with oral lesions that generally affects patients aged 40 - 60 years. The aim of this study was to report a case of pemphigus vulgaris presenting at an uncommon age with advanced periodontal disease, and to describe the treatment performed from the time of diagnosis through oral environment restoration and follow-up monitoring. One gingival vesicular lesion was biopsied. After the histological confirmation of pemphigus vulgaris, the patient was referred to a specialist for treatment of this systemic disease. With the improvement of the patient's clinical condition, teeth were extracted and oral rehabilitation was performed. The patient is being followed and is taking the appropriate medication. A direct immunofluorescence test was performed, but the patient had already started treatment with immunosuppressive medication at the time of the perilesional biopsy. The result of this test was negative. Pemphigus vulgaris manifests as extremely painful and persistent oral lesions. Thus, patient motivation to maintain oral health, preventive measures and the promotion of oral health, should be prioritized to avoid the worsening of the patient's systemic condition.
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spelling Pemphigus vulgaris in adolescence: a case reportPemphigus Vulgar en la adolescencia: reporte de un casoPeriodontal diseasesPemphigusAutoimmune diseasesAdolescentPathologyEnfermedades periodontalesPemphigus vulgarEnfermedades autoinmunesAdolescentePatologíaPemphigus vulgaris is an autoimmune disease, normally associated with oral lesions that generally affects patients aged 40 - 60 years. The aim of this study was to report a case of pemphigus vulgaris presenting at an uncommon age with advanced periodontal disease, and to describe the treatment performed from the time of diagnosis through oral environment restoration and follow-up monitoring. One gingival vesicular lesion was biopsied. After the histological confirmation of pemphigus vulgaris, the patient was referred to a specialist for treatment of this systemic disease. With the improvement of the patient's clinical condition, teeth were extracted and oral rehabilitation was performed. The patient is being followed and is taking the appropriate medication. A direct immunofluorescence test was performed, but the patient had already started treatment with immunosuppressive medication at the time of the perilesional biopsy. The result of this test was negative. Pemphigus vulgaris manifests as extremely painful and persistent oral lesions. Thus, patient motivation to maintain oral health, preventive measures and the promotion of oral health, should be prioritized to avoid the worsening of the patient's systemic condition.El pemphigus vulgar es una enfermedad autoinmune, que normalmente está asociada con lesiones orales que afectan a pacientes de 40 a 60 años. El objetivo de este trabajo es presentar un caso de pénfigo vulgar en una edad poco común con enfermedad periodontal avanzada, así como describir el tratamiento realizado desde el momento del diagnóstico, restauración de la salud oral y el seguimiento del monitoreo. Se realizó la biopsia de una lesión vesicular gingival. Después de la confirmación histológica del pemphigus vulgar, el paciente fue presentado a un especialista para el tratamiento de esta enfermedad sistémica. Con la mejora de la condición clínica del paciente, los dientes fueron extraídos y se realizó la rehabilitación oral. El paciente está siendo acompañado y tomando la medicación apropiada. Fue realizado el exámen de inmunofluorescencia directa, pero el paciente ya había comenzado el tratamiento con medicamentos inmunosupresores en el momento de la biopsia perilesional. El resultado de este examen fue negativo. El pemphigus vulgar se manifiesta en forma de lesiones orales extremadamente dolorosas y persistentes. Por lo tanto, la motivación del paciente para mantener la salud oral, las medidas de prevención y promoción de la salud oral deben ser priorizadas para evitar el empeoramiento de la condición sistémica del paciente.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Infantil e Social, Araçatuba, Rua José Bonifácio, 1193, Vila Mendonça, CEP 16015050, SP, BrasilImplant Dentistry and Surgery Disciplines, Faculty of Dentistry, Integrated Schools of Adamantina, FAI, Adamantina, São Paulo State, BrazilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Infantil e Social, Araçatuba, Rua José Bonifácio, 1193, Vila Mendonça, CEP 16015050, SP, BrasilUniversidade Estadual Paulista (Unesp)Faculdades Adamantinenses Integradas (FAI)Ferreira, Jean Paulo Rodolfo [UNESP]Araújo, Paula Caetano [UNESP]Saliba, Marcos Tadeu AdasConsolaro, Renata Bianco [UNESP]Garbin, Cléa Adas Saliba [UNESP]2016-01-28T16:54:58Z2016-01-28T16:54:58Z2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article215-220application/pdfhttp://dx.doi.org/10.4067/S0718-381X2013000200009International Journal of Odontostomatology, v. 7, n. 2, p. 215-220, 2013.0718-3801http://hdl.handle.net/11449/13340210.4067/S0718-381X2013000200009S0718-381X2013000200009S0718-381X2013000200009.pdf578043993368770744191585257096860000-0001-5069-8812Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Odontostomatologyinfo:eu-repo/semantics/openAccess2023-11-20T06:13:20Zoai:repositorio.unesp.br:11449/133402Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:15:10.234724Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Pemphigus vulgaris in adolescence: a case report
Pemphigus Vulgar en la adolescencia: reporte de un caso
title Pemphigus vulgaris in adolescence: a case report
spellingShingle Pemphigus vulgaris in adolescence: a case report
Ferreira, Jean Paulo Rodolfo [UNESP]
Periodontal diseases
Pemphigus
Autoimmune diseases
Adolescent
Pathology
Enfermedades periodontales
Pemphigus vulgar
Enfermedades autoinmunes
Adolescente
Patología
title_short Pemphigus vulgaris in adolescence: a case report
title_full Pemphigus vulgaris in adolescence: a case report
title_fullStr Pemphigus vulgaris in adolescence: a case report
title_full_unstemmed Pemphigus vulgaris in adolescence: a case report
title_sort Pemphigus vulgaris in adolescence: a case report
author Ferreira, Jean Paulo Rodolfo [UNESP]
author_facet Ferreira, Jean Paulo Rodolfo [UNESP]
Araújo, Paula Caetano [UNESP]
Saliba, Marcos Tadeu Adas
Consolaro, Renata Bianco [UNESP]
Garbin, Cléa Adas Saliba [UNESP]
author_role author
author2 Araújo, Paula Caetano [UNESP]
Saliba, Marcos Tadeu Adas
Consolaro, Renata Bianco [UNESP]
Garbin, Cléa Adas Saliba [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Faculdades Adamantinenses Integradas (FAI)
dc.contributor.author.fl_str_mv Ferreira, Jean Paulo Rodolfo [UNESP]
Araújo, Paula Caetano [UNESP]
Saliba, Marcos Tadeu Adas
Consolaro, Renata Bianco [UNESP]
Garbin, Cléa Adas Saliba [UNESP]
dc.subject.por.fl_str_mv Periodontal diseases
Pemphigus
Autoimmune diseases
Adolescent
Pathology
Enfermedades periodontales
Pemphigus vulgar
Enfermedades autoinmunes
Adolescente
Patología
topic Periodontal diseases
Pemphigus
Autoimmune diseases
Adolescent
Pathology
Enfermedades periodontales
Pemphigus vulgar
Enfermedades autoinmunes
Adolescente
Patología
description Pemphigus vulgaris is an autoimmune disease, normally associated with oral lesions that generally affects patients aged 40 - 60 years. The aim of this study was to report a case of pemphigus vulgaris presenting at an uncommon age with advanced periodontal disease, and to describe the treatment performed from the time of diagnosis through oral environment restoration and follow-up monitoring. One gingival vesicular lesion was biopsied. After the histological confirmation of pemphigus vulgaris, the patient was referred to a specialist for treatment of this systemic disease. With the improvement of the patient's clinical condition, teeth were extracted and oral rehabilitation was performed. The patient is being followed and is taking the appropriate medication. A direct immunofluorescence test was performed, but the patient had already started treatment with immunosuppressive medication at the time of the perilesional biopsy. The result of this test was negative. Pemphigus vulgaris manifests as extremely painful and persistent oral lesions. Thus, patient motivation to maintain oral health, preventive measures and the promotion of oral health, should be prioritized to avoid the worsening of the patient's systemic condition.
publishDate 2013
dc.date.none.fl_str_mv 2013
2016-01-28T16:54:58Z
2016-01-28T16:54:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4067/S0718-381X2013000200009
International Journal of Odontostomatology, v. 7, n. 2, p. 215-220, 2013.
0718-3801
http://hdl.handle.net/11449/133402
10.4067/S0718-381X2013000200009
S0718-381X2013000200009
S0718-381X2013000200009.pdf
5780439933687707
4419158525709686
0000-0001-5069-8812
url http://dx.doi.org/10.4067/S0718-381X2013000200009
http://hdl.handle.net/11449/133402
identifier_str_mv International Journal of Odontostomatology, v. 7, n. 2, p. 215-220, 2013.
0718-3801
10.4067/S0718-381X2013000200009
S0718-381X2013000200009
S0718-381X2013000200009.pdf
5780439933687707
4419158525709686
0000-0001-5069-8812
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal of Odontostomatology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 215-220
application/pdf
dc.source.none.fl_str_mv Currículo Lattes
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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