Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance

Detalhes bibliográficos
Autor(a) principal: de Rond, Veerle
Data de Publicação: 2021
Outros Autores: Orcioli-Silva, Diego [UNESP], Dijkstra, Bauke Wybren, Orban de Xivry, Jean-Jacques, Pantall, Annette, Nieuwboer, Alice
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3389/fnagi.2021.657308
http://hdl.handle.net/11449/222012
Resumo: Background: Postural control and cognition are affected by aging. We investigated whether cognitive distraction influenced neural activity differently in young and older adults during a game-like mediolateral weight-shifting task with a personalized task load. Methods: Seventeen healthy young and 17 older adults performed a balance game, involving hitting virtual wasps, serial subtractions and a combination of both (dual-task). A motion analysis system estimated each subject's center of mass position. Cortical activity in five regions was assessed by measuring oxygenated hemoglobin (HbO2) with a functional Near-Infrared Spectroscopy system. Results: When adding cognitive load to the game, weight-shifting speed decreased irrespective of age, but older adults reduced the wasp-hits more than young adults. Accompanying these changes, older adults decreased HbO2 in the left pre-frontal cortex (PFC) and frontal eye fields (FEF) compared to single-tasking, a finding not seen in young adults. Additionally, lower HbO2 levels were found during dual-tasking compared to the summed activation of the two single tasks in all regions except for the right PFC. These relative reductions were specific for the older age group in the left premotor cortex (PMC), the right supplementary motor area (SMA), and the left FEF. Conclusion: Older adults showed more compromised neural activity than young adults when adding a distraction to a challenging balance game. We interpret these changes as competitive downgrading of neural activity underpinning the age-related deterioration of game performance during dual-tasking. Future work needs to ascertain if older adults can train their neural flexibility to withstand balance challenges during daily life activities.
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spelling Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performanceagingcognitive loaddual-taskfNIRSpostural controlweight-shiftingBackground: Postural control and cognition are affected by aging. We investigated whether cognitive distraction influenced neural activity differently in young and older adults during a game-like mediolateral weight-shifting task with a personalized task load. Methods: Seventeen healthy young and 17 older adults performed a balance game, involving hitting virtual wasps, serial subtractions and a combination of both (dual-task). A motion analysis system estimated each subject's center of mass position. Cortical activity in five regions was assessed by measuring oxygenated hemoglobin (HbO2) with a functional Near-Infrared Spectroscopy system. Results: When adding cognitive load to the game, weight-shifting speed decreased irrespective of age, but older adults reduced the wasp-hits more than young adults. Accompanying these changes, older adults decreased HbO2 in the left pre-frontal cortex (PFC) and frontal eye fields (FEF) compared to single-tasking, a finding not seen in young adults. Additionally, lower HbO2 levels were found during dual-tasking compared to the summed activation of the two single tasks in all regions except for the right PFC. These relative reductions were specific for the older age group in the left premotor cortex (PMC), the right supplementary motor area (SMA), and the left FEF. Conclusion: Older adults showed more compromised neural activity than young adults when adding a distraction to a challenging balance game. We interpret these changes as competitive downgrading of neural activity underpinning the age-related deterioration of game performance during dual-tasking. Future work needs to ascertain if older adults can train their neural flexibility to withstand balance challenges during daily life activities.Neuromotor Rehabilitation Research Group Department of Rehabilitation Sciences KU LeuvenPosture and Gait Studies Laboratory (LEPLO) Institute of Biosciences São Paulo State University (UNESP)Motor Control and Neuroplasticity Research Group Department of Movement Sciences KU LeuvenLeuven Brain InstituteClinical Ageing Research Unit Institute of Neuroscience Newcastle University Institute of AgeingPosture and Gait Studies Laboratory (LEPLO) Institute of Biosciences São Paulo State University (UNESP)KU LeuvenUniversidade Estadual Paulista (UNESP)Leuven Brain InstituteNewcastle University Institute of Ageingde Rond, VeerleOrcioli-Silva, Diego [UNESP]Dijkstra, Bauke WybrenOrban de Xivry, Jean-JacquesPantall, AnnetteNieuwboer, Alice2022-04-28T19:41:56Z2022-04-28T19:41:56Z2021-07-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3389/fnagi.2021.657308Frontiers in Aging Neuroscience, v. 13.1663-4365http://hdl.handle.net/11449/22201210.3389/fnagi.2021.6573082-s2.0-85110914880Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Aging Neuroscienceinfo:eu-repo/semantics/openAccess2022-04-28T19:41:56Zoai:repositorio.unesp.br:11449/222012Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:45:31.942816Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
title Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
spellingShingle Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
de Rond, Veerle
aging
cognitive load
dual-task
fNIRS
postural control
weight-shifting
title_short Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
title_full Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
title_fullStr Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
title_full_unstemmed Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
title_sort Compromised Brain Activity With Age During a Game-Like Dynamic Balance Task: Single- vs. Dual-Task Performance
author de Rond, Veerle
author_facet de Rond, Veerle
Orcioli-Silva, Diego [UNESP]
Dijkstra, Bauke Wybren
Orban de Xivry, Jean-Jacques
Pantall, Annette
Nieuwboer, Alice
author_role author
author2 Orcioli-Silva, Diego [UNESP]
Dijkstra, Bauke Wybren
Orban de Xivry, Jean-Jacques
Pantall, Annette
Nieuwboer, Alice
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv KU Leuven
Universidade Estadual Paulista (UNESP)
Leuven Brain Institute
Newcastle University Institute of Ageing
dc.contributor.author.fl_str_mv de Rond, Veerle
Orcioli-Silva, Diego [UNESP]
Dijkstra, Bauke Wybren
Orban de Xivry, Jean-Jacques
Pantall, Annette
Nieuwboer, Alice
dc.subject.por.fl_str_mv aging
cognitive load
dual-task
fNIRS
postural control
weight-shifting
topic aging
cognitive load
dual-task
fNIRS
postural control
weight-shifting
description Background: Postural control and cognition are affected by aging. We investigated whether cognitive distraction influenced neural activity differently in young and older adults during a game-like mediolateral weight-shifting task with a personalized task load. Methods: Seventeen healthy young and 17 older adults performed a balance game, involving hitting virtual wasps, serial subtractions and a combination of both (dual-task). A motion analysis system estimated each subject's center of mass position. Cortical activity in five regions was assessed by measuring oxygenated hemoglobin (HbO2) with a functional Near-Infrared Spectroscopy system. Results: When adding cognitive load to the game, weight-shifting speed decreased irrespective of age, but older adults reduced the wasp-hits more than young adults. Accompanying these changes, older adults decreased HbO2 in the left pre-frontal cortex (PFC) and frontal eye fields (FEF) compared to single-tasking, a finding not seen in young adults. Additionally, lower HbO2 levels were found during dual-tasking compared to the summed activation of the two single tasks in all regions except for the right PFC. These relative reductions were specific for the older age group in the left premotor cortex (PMC), the right supplementary motor area (SMA), and the left FEF. Conclusion: Older adults showed more compromised neural activity than young adults when adding a distraction to a challenging balance game. We interpret these changes as competitive downgrading of neural activity underpinning the age-related deterioration of game performance during dual-tasking. Future work needs to ascertain if older adults can train their neural flexibility to withstand balance challenges during daily life activities.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-05
2022-04-28T19:41:56Z
2022-04-28T19:41:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3389/fnagi.2021.657308
Frontiers in Aging Neuroscience, v. 13.
1663-4365
http://hdl.handle.net/11449/222012
10.3389/fnagi.2021.657308
2-s2.0-85110914880
url http://dx.doi.org/10.3389/fnagi.2021.657308
http://hdl.handle.net/11449/222012
identifier_str_mv Frontiers in Aging Neuroscience, v. 13.
1663-4365
10.3389/fnagi.2021.657308
2-s2.0-85110914880
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Frontiers in Aging Neuroscience
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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