Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.rvsc.2018.10.004 http://hdl.handle.net/11449/189784 |
Resumo: | Few data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70–80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P <.05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P <.05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P <.05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury. |
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Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogsaspartate aminotransferasecardiac troponin Icreatine kinaseheart ratelactatemyoglobinFew data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70–80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P <.05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P <.05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P <.05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury.São Paulo State University (UNESP) School of Agricultural and Veterinarian Sciences JaboticabalSão Paulo State University (UNESP) School of Agricultural and Veterinarian Sciences JaboticabalUniversidade Estadual Paulista (Unesp)Cerqueira, Juliana Aparecida [UNESP]Restan, Wilmer Alejandro Zamora [UNESP]Fonseca, Mayara Gonçalves [UNESP]Catananti, Lucas Azevedo [UNESP]de Almeida, Maria Luiza Mendes [UNESP]Junior, Walter Heinz Feringer [UNESP]Pereira, Gener Tadeu [UNESP]Carciofi, Aulus Cavalieri [UNESP]de Camargo Ferraz, Guilherme [UNESP]2019-10-06T16:52:02Z2019-10-06T16:52:02Z2018-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article31-39http://dx.doi.org/10.1016/j.rvsc.2018.10.004Research in Veterinary Science, v. 121, p. 31-39.1532-26610034-5288http://hdl.handle.net/11449/18978410.1016/j.rvsc.2018.10.0042-s2.0-85054460823Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengResearch in Veterinary Scienceinfo:eu-repo/semantics/openAccess2024-06-06T14:09:12Zoai:repositorio.unesp.br:11449/189784Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:37:27.898492Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
spellingShingle |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs Cerqueira, Juliana Aparecida [UNESP] aspartate aminotransferase cardiac troponin I creatine kinase heart rate lactate myoglobin |
title_short |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_full |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_fullStr |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_full_unstemmed |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_sort |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
author |
Cerqueira, Juliana Aparecida [UNESP] |
author_facet |
Cerqueira, Juliana Aparecida [UNESP] Restan, Wilmer Alejandro Zamora [UNESP] Fonseca, Mayara Gonçalves [UNESP] Catananti, Lucas Azevedo [UNESP] de Almeida, Maria Luiza Mendes [UNESP] Junior, Walter Heinz Feringer [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] de Camargo Ferraz, Guilherme [UNESP] |
author_role |
author |
author2 |
Restan, Wilmer Alejandro Zamora [UNESP] Fonseca, Mayara Gonçalves [UNESP] Catananti, Lucas Azevedo [UNESP] de Almeida, Maria Luiza Mendes [UNESP] Junior, Walter Heinz Feringer [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] de Camargo Ferraz, Guilherme [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Cerqueira, Juliana Aparecida [UNESP] Restan, Wilmer Alejandro Zamora [UNESP] Fonseca, Mayara Gonçalves [UNESP] Catananti, Lucas Azevedo [UNESP] de Almeida, Maria Luiza Mendes [UNESP] Junior, Walter Heinz Feringer [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] de Camargo Ferraz, Guilherme [UNESP] |
dc.subject.por.fl_str_mv |
aspartate aminotransferase cardiac troponin I creatine kinase heart rate lactate myoglobin |
topic |
aspartate aminotransferase cardiac troponin I creatine kinase heart rate lactate myoglobin |
description |
Few data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70–80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P <.05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P <.05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P <.05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 2019-10-06T16:52:02Z 2019-10-06T16:52:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.rvsc.2018.10.004 Research in Veterinary Science, v. 121, p. 31-39. 1532-2661 0034-5288 http://hdl.handle.net/11449/189784 10.1016/j.rvsc.2018.10.004 2-s2.0-85054460823 |
url |
http://dx.doi.org/10.1016/j.rvsc.2018.10.004 http://hdl.handle.net/11449/189784 |
identifier_str_mv |
Research in Veterinary Science, v. 121, p. 31-39. 1532-2661 0034-5288 10.1016/j.rvsc.2018.10.004 2-s2.0-85054460823 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Research in Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
31-39 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128540929949696 |