Biocompatibility of different intracanal medications in rat buccal submucosa tissue

Detalhes bibliográficos
Autor(a) principal: Delle Vedove Semenoff, Tereza Aparecida [UNESP]
Data de Publicação: 2008
Outros Autores: Segundo, Alex Semenoff [UNESP], Poli de Figueiredo, Jose Antonio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-77572008000100004
http://hdl.handle.net/11449/41681
Resumo: The aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was per-formed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals.
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spelling Biocompatibility of different intracanal medications in rat buccal submucosa tissuebiocompatibilitycalcium hydroxidechlorhexidineendodonticsratsThe aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was per-formed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals.São Paulo State Univ, Aracatuba Sch Dent, Aracatuba, SP, BrazilUniversidade Federal do Rio Grande do Sul (UFRGS), Sch Dent, Porto Alegre, RS, BrazilSão Paulo State Univ, Aracatuba Sch Dent, Aracatuba, SP, BrazilUniversidade de São Paulo (USP), Faculdade de Odontologia de BauruUniversidade Estadual Paulista (Unesp)Universidade Federal do Rio Grande do Sul (UFRGS)Delle Vedove Semenoff, Tereza Aparecida [UNESP]Segundo, Alex Semenoff [UNESP]Poli de Figueiredo, Jose Antonio2014-05-20T15:32:54Z2014-05-20T15:32:54Z2008-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1590/S1678-77572008000100004Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 16, n. 1, p. 12-17, 2008.1678-7757http://hdl.handle.net/11449/41681S1678-77572008000100004WOS:000256795300003S1678-77572008000100004.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-11-20T06:11:28Zoai:repositorio.unesp.br:11449/41681Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:12:57.050845Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Biocompatibility of different intracanal medications in rat buccal submucosa tissue
title Biocompatibility of different intracanal medications in rat buccal submucosa tissue
spellingShingle Biocompatibility of different intracanal medications in rat buccal submucosa tissue
Delle Vedove Semenoff, Tereza Aparecida [UNESP]
biocompatibility
calcium hydroxide
chlorhexidine
endodontics
rats
title_short Biocompatibility of different intracanal medications in rat buccal submucosa tissue
title_full Biocompatibility of different intracanal medications in rat buccal submucosa tissue
title_fullStr Biocompatibility of different intracanal medications in rat buccal submucosa tissue
title_full_unstemmed Biocompatibility of different intracanal medications in rat buccal submucosa tissue
title_sort Biocompatibility of different intracanal medications in rat buccal submucosa tissue
author Delle Vedove Semenoff, Tereza Aparecida [UNESP]
author_facet Delle Vedove Semenoff, Tereza Aparecida [UNESP]
Segundo, Alex Semenoff [UNESP]
Poli de Figueiredo, Jose Antonio
author_role author
author2 Segundo, Alex Semenoff [UNESP]
Poli de Figueiredo, Jose Antonio
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal do Rio Grande do Sul (UFRGS)
dc.contributor.author.fl_str_mv Delle Vedove Semenoff, Tereza Aparecida [UNESP]
Segundo, Alex Semenoff [UNESP]
Poli de Figueiredo, Jose Antonio
dc.subject.por.fl_str_mv biocompatibility
calcium hydroxide
chlorhexidine
endodontics
rats
topic biocompatibility
calcium hydroxide
chlorhexidine
endodontics
rats
description The aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was per-formed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
2014-05-20T15:32:54Z
2014-05-20T15:32:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-77572008000100004
Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 16, n. 1, p. 12-17, 2008.
1678-7757
http://hdl.handle.net/11449/41681
S1678-77572008000100004
WOS:000256795300003
S1678-77572008000100004.pdf
url http://dx.doi.org/10.1590/S1678-77572008000100004
http://hdl.handle.net/11449/41681
identifier_str_mv Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 16, n. 1, p. 12-17, 2008.
1678-7757
S1678-77572008000100004
WOS:000256795300003
S1678-77572008000100004.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Applied Oral Science
1.709
0,645
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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