Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults

Detalhes bibliográficos
Autor(a) principal: de Oliveira, Elaine Aparecida [UNESP]
Data de Publicação: 2018
Outros Autores: da Silva, Anne Kastelianne França [UNESP], Christofaro, Diego Giuliano Destro [UNESP], Vanzella, Laís Manata [UNESP], Gomes, Rayana Loch [UNESP], Vanderlei, Franciele Marques [UNESP], Vanderlei, Luiz Carlos Marques [UNESP]
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.5935/abc.20180117
http://hdl.handle.net/11449/180130
Resumo: Background: Type 1 diabetes mellitus can cause autonomic changes, which can be assessed by heart rate variability. Among the heart rate variability assessment methods, the symbolic analysis and Shannon entropy, based on the Chaotic dynamics, have gained prominence. Objective: To compare heart rate variability indexes, obtained through symbolic analysis and Shannon entropy, in young adults with type 1 diabetes mellitus and healthy young individuals, associated with the analysis of linear indexes; and to verify if there are associations between the indexes obtained by the symbolic analysis and by Shannon entropy and linear indexes in diabetic individuals. Methods: Heart rate variability data from 39 young adults with type 1 diabetes mellitus and 43 healthy young individuals were analyzed, using a cardio-frequency meter. Linear indexes (standard deviation of all normal RR intervals recorded in a time interval expressed in milliseconds; square root of the mean of the squared differences between adjacent normal RR intervals in a time interval expressed in milliseconds; low and high frequency components in millisecond squared; and normalized units and ratio between low and high frequency components) and nonlinear ones (Shannon entropy and symbolic analysis – standard without variation; with one or two variations; and with two different variations) of the heart rate variability were calculated. The statistical significance was set at 5%, and the confidence interval was 95%. Results: Significantly lower values were observed in the DM1 group compared to healthy young adults for the standard deviation indexes of all normal RR intervals recorded in a time interval [37.30 (29.90) vs. 64.50 (36.20); p = 0.0001], square root of the mean of the squared differences between adjacent normal RR intervals in a time interval [32.73 (17.43) vs. 55.59 (21.60); p = 0.0001], low frequency component [402.00 (531.00) vs. 1,203.00 (1,148.00); p = 0.0001], high frequency component [386.00 (583.00) vs. 963.00 (866.00); p = 0.0001] and the pattern with two different variations [15,33 (9,22) vs. 20.24 (12.73); p = 0.0114], with the effect of this difference being considered large (standard deviation of all normal RR intervals recorded in a time interval, square root of the mean of the squared differences between adjacent normal RR intervals in a time interval and low frequency component), medium (high frequency component) and small (standard with two different variations). The agreement of the associations between the linear and non-linear indexes was considered elevated for the high frequency component index - normalized units (r = –0.776), with the standard index without variation, and moderate for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.550), standard deviation of all normal RR intervals recorded in a time interval (r = 0.522), high frequency component - normalized units (r = 0.638) with the index standard with two similar variations, as well as for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.627) and high frequency component - normalized units (r = 0.601) with the index standard with two different variations. Conclusion: Type 1 diabetes mellitus influenced linear indexes and symbolic analysis, but not yet in the complexity of heart rate variability. Additionally, heart rate variability indexes correlated with the symbolic dynamics.
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spelling Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adultsInfluência do diabetes tipo 1 na análise simbólica e complexidade da variabilidade da frequência cardíaca em jovens adultosAutonomic nervous systemDiabetes mellitus/complicationsDiabetes/diagnosisDiabetes/therapyHeart rateYoung adultBackground: Type 1 diabetes mellitus can cause autonomic changes, which can be assessed by heart rate variability. Among the heart rate variability assessment methods, the symbolic analysis and Shannon entropy, based on the Chaotic dynamics, have gained prominence. Objective: To compare heart rate variability indexes, obtained through symbolic analysis and Shannon entropy, in young adults with type 1 diabetes mellitus and healthy young individuals, associated with the analysis of linear indexes; and to verify if there are associations between the indexes obtained by the symbolic analysis and by Shannon entropy and linear indexes in diabetic individuals. Methods: Heart rate variability data from 39 young adults with type 1 diabetes mellitus and 43 healthy young individuals were analyzed, using a cardio-frequency meter. Linear indexes (standard deviation of all normal RR intervals recorded in a time interval expressed in milliseconds; square root of the mean of the squared differences between adjacent normal RR intervals in a time interval expressed in milliseconds; low and high frequency components in millisecond squared; and normalized units and ratio between low and high frequency components) and nonlinear ones (Shannon entropy and symbolic analysis – standard without variation; with one or two variations; and with two different variations) of the heart rate variability were calculated. The statistical significance was set at 5%, and the confidence interval was 95%. Results: Significantly lower values were observed in the DM1 group compared to healthy young adults for the standard deviation indexes of all normal RR intervals recorded in a time interval [37.30 (29.90) vs. 64.50 (36.20); p = 0.0001], square root of the mean of the squared differences between adjacent normal RR intervals in a time interval [32.73 (17.43) vs. 55.59 (21.60); p = 0.0001], low frequency component [402.00 (531.00) vs. 1,203.00 (1,148.00); p = 0.0001], high frequency component [386.00 (583.00) vs. 963.00 (866.00); p = 0.0001] and the pattern with two different variations [15,33 (9,22) vs. 20.24 (12.73); p = 0.0114], with the effect of this difference being considered large (standard deviation of all normal RR intervals recorded in a time interval, square root of the mean of the squared differences between adjacent normal RR intervals in a time interval and low frequency component), medium (high frequency component) and small (standard with two different variations). The agreement of the associations between the linear and non-linear indexes was considered elevated for the high frequency component index - normalized units (r = –0.776), with the standard index without variation, and moderate for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.550), standard deviation of all normal RR intervals recorded in a time interval (r = 0.522), high frequency component - normalized units (r = 0.638) with the index standard with two similar variations, as well as for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.627) and high frequency component - normalized units (r = 0.601) with the index standard with two different variations. Conclusion: Type 1 diabetes mellitus influenced linear indexes and symbolic analysis, but not yet in the complexity of heart rate variability. Additionally, heart rate variability indexes correlated with the symbolic dynamics.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)FAPESP: 2013/19055-0Universidade Estadual Paulista (Unesp)de Oliveira, Elaine Aparecida [UNESP]da Silva, Anne Kastelianne França [UNESP]Christofaro, Diego Giuliano Destro [UNESP]Vanzella, Laís Manata [UNESP]Gomes, Rayana Loch [UNESP]Vanderlei, Franciele Marques [UNESP]Vanderlei, Luiz Carlos Marques [UNESP]2018-12-11T17:38:17Z2018-12-11T17:38:17Z2018-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article94-101application/pdfhttp://dx.doi.org/10.5935/abc.20180117Arquivos Brasileiros de Cardiologia, v. 111, n. 1, p. 94-101, 2018.1678-41700066-782Xhttp://hdl.handle.net/11449/18013010.5935/abc.20180117S0066-782X20180013000942-s2.0-85052322210S0066-782X2018001300094.pdf5860525135106995Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporArquivos Brasileiros de Cardiologiainfo:eu-repo/semantics/openAccess2024-06-18T18:44:01Zoai:repositorio.unesp.br:11449/180130Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:47:44.504610Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
Influência do diabetes tipo 1 na análise simbólica e complexidade da variabilidade da frequência cardíaca em jovens adultos
title Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
spellingShingle Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
de Oliveira, Elaine Aparecida [UNESP]
Autonomic nervous system
Diabetes mellitus/complications
Diabetes/diagnosis
Diabetes/therapy
Heart rate
Young adult
title_short Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
title_full Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
title_fullStr Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
title_full_unstemmed Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
title_sort Influence of type 1 diabetes on the symbolic analysis and complexity of heart rate variability in young adults
author de Oliveira, Elaine Aparecida [UNESP]
author_facet de Oliveira, Elaine Aparecida [UNESP]
da Silva, Anne Kastelianne França [UNESP]
Christofaro, Diego Giuliano Destro [UNESP]
Vanzella, Laís Manata [UNESP]
Gomes, Rayana Loch [UNESP]
Vanderlei, Franciele Marques [UNESP]
Vanderlei, Luiz Carlos Marques [UNESP]
author_role author
author2 da Silva, Anne Kastelianne França [UNESP]
Christofaro, Diego Giuliano Destro [UNESP]
Vanzella, Laís Manata [UNESP]
Gomes, Rayana Loch [UNESP]
Vanderlei, Franciele Marques [UNESP]
Vanderlei, Luiz Carlos Marques [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv de Oliveira, Elaine Aparecida [UNESP]
da Silva, Anne Kastelianne França [UNESP]
Christofaro, Diego Giuliano Destro [UNESP]
Vanzella, Laís Manata [UNESP]
Gomes, Rayana Loch [UNESP]
Vanderlei, Franciele Marques [UNESP]
Vanderlei, Luiz Carlos Marques [UNESP]
dc.subject.por.fl_str_mv Autonomic nervous system
Diabetes mellitus/complications
Diabetes/diagnosis
Diabetes/therapy
Heart rate
Young adult
topic Autonomic nervous system
Diabetes mellitus/complications
Diabetes/diagnosis
Diabetes/therapy
Heart rate
Young adult
description Background: Type 1 diabetes mellitus can cause autonomic changes, which can be assessed by heart rate variability. Among the heart rate variability assessment methods, the symbolic analysis and Shannon entropy, based on the Chaotic dynamics, have gained prominence. Objective: To compare heart rate variability indexes, obtained through symbolic analysis and Shannon entropy, in young adults with type 1 diabetes mellitus and healthy young individuals, associated with the analysis of linear indexes; and to verify if there are associations between the indexes obtained by the symbolic analysis and by Shannon entropy and linear indexes in diabetic individuals. Methods: Heart rate variability data from 39 young adults with type 1 diabetes mellitus and 43 healthy young individuals were analyzed, using a cardio-frequency meter. Linear indexes (standard deviation of all normal RR intervals recorded in a time interval expressed in milliseconds; square root of the mean of the squared differences between adjacent normal RR intervals in a time interval expressed in milliseconds; low and high frequency components in millisecond squared; and normalized units and ratio between low and high frequency components) and nonlinear ones (Shannon entropy and symbolic analysis – standard without variation; with one or two variations; and with two different variations) of the heart rate variability were calculated. The statistical significance was set at 5%, and the confidence interval was 95%. Results: Significantly lower values were observed in the DM1 group compared to healthy young adults for the standard deviation indexes of all normal RR intervals recorded in a time interval [37.30 (29.90) vs. 64.50 (36.20); p = 0.0001], square root of the mean of the squared differences between adjacent normal RR intervals in a time interval [32.73 (17.43) vs. 55.59 (21.60); p = 0.0001], low frequency component [402.00 (531.00) vs. 1,203.00 (1,148.00); p = 0.0001], high frequency component [386.00 (583.00) vs. 963.00 (866.00); p = 0.0001] and the pattern with two different variations [15,33 (9,22) vs. 20.24 (12.73); p = 0.0114], with the effect of this difference being considered large (standard deviation of all normal RR intervals recorded in a time interval, square root of the mean of the squared differences between adjacent normal RR intervals in a time interval and low frequency component), medium (high frequency component) and small (standard with two different variations). The agreement of the associations between the linear and non-linear indexes was considered elevated for the high frequency component index - normalized units (r = –0.776), with the standard index without variation, and moderate for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.550), standard deviation of all normal RR intervals recorded in a time interval (r = 0.522), high frequency component - normalized units (r = 0.638) with the index standard with two similar variations, as well as for the indexes square root of the mean of the squared differences between adjacent normal RR intervals in a time interval (r = 0.627) and high frequency component - normalized units (r = 0.601) with the index standard with two different variations. Conclusion: Type 1 diabetes mellitus influenced linear indexes and symbolic analysis, but not yet in the complexity of heart rate variability. Additionally, heart rate variability indexes correlated with the symbolic dynamics.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:38:17Z
2018-12-11T17:38:17Z
2018-07-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5935/abc.20180117
Arquivos Brasileiros de Cardiologia, v. 111, n. 1, p. 94-101, 2018.
1678-4170
0066-782X
http://hdl.handle.net/11449/180130
10.5935/abc.20180117
S0066-782X2018001300094
2-s2.0-85052322210
S0066-782X2018001300094.pdf
5860525135106995
url http://dx.doi.org/10.5935/abc.20180117
http://hdl.handle.net/11449/180130
identifier_str_mv Arquivos Brasileiros de Cardiologia, v. 111, n. 1, p. 94-101, 2018.
1678-4170
0066-782X
10.5935/abc.20180117
S0066-782X2018001300094
2-s2.0-85052322210
S0066-782X2018001300094.pdf
5860525135106995
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Cardiologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 94-101
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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