The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.bjm.2018.03.003 http://hdl.handle.net/11449/184972 |
Resumo: | Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 mu mol mL(-1) respectively. Captan and difenocona-zole were included as positive controls (MIC 16.63 and 0.02 mu mol mL(-1), respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. (C) 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. |
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The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose2-Hexylidene-3-methylbutanedioic acidAmazonAnthracnosePlant pathogenAnthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 mu mol mL(-1) respectively. Captan and difenocona-zole were included as positive controls (MIC 16.63 and 0.02 mu mol mL(-1), respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. (C) 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Sao Paulo, Dept Ciencias Exatas, Escola Super Agr Luiz de Queiroz, Piracicaba, SP, BrazilUniv Sao Paulo, Dept Genet, Escola Super Agr Luiz de Queiroz, Piracicaba, SP, BrazilUniv Estadual Paulista, Inst Biociencias, Dept Bioquim & Microbiol, Rio Claro, SP, BrazilUniv Fed Sao Carlos, Dept Quim, Sao Carlos, SP, BrazilUniv Estadual Paulista, Inst Biociencias, Dept Bioquim & Microbiol, Rio Claro, SP, BrazilFAPESP: 2014/15760-3FAPESP: 2013/50228-8CNPq: 142079/2016-2: FAPESP: 2012/02000-5: FAPESP: 2014/05940-4SpringerUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Universidade Federal de São Carlos (UFSCar)Elias, Luciana M.Fortlzamp, DianaSartori, Sergio B.Ferreira, Marilia C.Gomes, Luiz H.Azevedo, Joao L.Montoya, Quimi [UNESP]Rodrigues, Andre [UNESP]Ferreira, Antonio G.Lira, Simone P.2019-10-04T12:31:32Z2019-10-04T12:31:32Z2018-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article840-847application/pdfhttp://dx.doi.org/10.1016/j.bjm.2018.03.003Brazilian Journal Of Microbiology. New York: Springer, v. 49, n. 4, p. 840-847, 2018.1517-8382http://hdl.handle.net/11449/18497210.1016/j.bjm.2018.03.003S1517-83822018000400840WOS:000447893000020S1517-83822018000400840.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal Of Microbiologyinfo:eu-repo/semantics/openAccess2023-12-19T06:26:19Zoai:repositorio.unesp.br:11449/184972Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:46:39.799425Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
spellingShingle |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose Elias, Luciana M. 2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
title_short |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_full |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_fullStr |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_full_unstemmed |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_sort |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
author |
Elias, Luciana M. |
author_facet |
Elias, Luciana M. Fortlzamp, Diana Sartori, Sergio B. Ferreira, Marilia C. Gomes, Luiz H. Azevedo, Joao L. Montoya, Quimi [UNESP] Rodrigues, Andre [UNESP] Ferreira, Antonio G. Lira, Simone P. |
author_role |
author |
author2 |
Fortlzamp, Diana Sartori, Sergio B. Ferreira, Marilia C. Gomes, Luiz H. Azevedo, Joao L. Montoya, Quimi [UNESP] Rodrigues, Andre [UNESP] Ferreira, Antonio G. Lira, Simone P. |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) Universidade Federal de São Carlos (UFSCar) |
dc.contributor.author.fl_str_mv |
Elias, Luciana M. Fortlzamp, Diana Sartori, Sergio B. Ferreira, Marilia C. Gomes, Luiz H. Azevedo, Joao L. Montoya, Quimi [UNESP] Rodrigues, Andre [UNESP] Ferreira, Antonio G. Lira, Simone P. |
dc.subject.por.fl_str_mv |
2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
topic |
2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
description |
Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 mu mol mL(-1) respectively. Captan and difenocona-zole were included as positive controls (MIC 16.63 and 0.02 mu mol mL(-1), respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. (C) 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-10-01 2019-10-04T12:31:32Z 2019-10-04T12:31:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.bjm.2018.03.003 Brazilian Journal Of Microbiology. New York: Springer, v. 49, n. 4, p. 840-847, 2018. 1517-8382 http://hdl.handle.net/11449/184972 10.1016/j.bjm.2018.03.003 S1517-83822018000400840 WOS:000447893000020 S1517-83822018000400840.pdf |
url |
http://dx.doi.org/10.1016/j.bjm.2018.03.003 http://hdl.handle.net/11449/184972 |
identifier_str_mv |
Brazilian Journal Of Microbiology. New York: Springer, v. 49, n. 4, p. 840-847, 2018. 1517-8382 10.1016/j.bjm.2018.03.003 S1517-83822018000400840 WOS:000447893000020 S1517-83822018000400840.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal Of Microbiology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
840-847 application/pdf |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129247153225728 |