Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool

Detalhes bibliográficos
Autor(a) principal: Reis, Leonardo Oliveira
Data de Publicação: 2011
Outros Autores: Sopena, Josep Maria Gaya, Fávaro, Wagner José [UNESP], Martin, Mireia Castilho, Simão, Antônio Felipe Leite, Reis, Rodolfo Borges dos, Andrade, Murilo Ferreira de, Domenech, Josep Domingo, Cardo, Carlos Cordon
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0102-86502011000800019
http://hdl.handle.net/11449/72792
Resumo: PURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.
id UNSP_4f898aaf15a2e8daa846876eb83c361e
oai_identifier_str oai:repositorio.unesp.br:11449/72792
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational toolCaracterísticas anatômicas da cateterização da uretra e bexiga de camundongos e ratos fêmeas. instrumento essencial na pesquisa pré clínicaAnatomyRatsRodent diseasesUrinary tractanimal anatomyanimal experimentbladderbladder catheterizationcancer researchcarcinogenesiscost benefit analysisfemalemousenonhumanrattoxicity testingurethraurethral catheterizationvesicoureteral refluxAnimalsFemaleMedical IllustrationMiceModels, AnimalReproducibility of ResultsSex FactorsUrethraUrinary BladderUrinary CatheterizationPURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.Urologic Oncology Division Department of Urology University of Campinas (UNICAMP), Campinas-SPHerbert Irving Comprehensive Cancer Center Columbia University, New York, NYDepartment of Anatomy, Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-SPDivision of Urology Department of Surgery and Anatomy, Ribeirao Preto-SPUrologic Division Department of Surgery and Anatomy, FMRP-USP, Ribeirao Preto-SPHerbert Irving Comprehensive Cancer Center Columbia University, New York, New YorkDepartment of Anatomy, Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-SPUniversidade Estadual de Campinas (UNICAMP)Columbia UniversityUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Reis, Leonardo OliveiraSopena, Josep Maria GayaFávaro, Wagner José [UNESP]Martin, Mireia CastilhoSimão, Antônio Felipe LeiteReis, Rodolfo Borges dosAndrade, Murilo Ferreira deDomenech, Josep DomingoCardo, Carlos Cordon2014-05-27T11:26:07Z2014-05-27T11:26:07Z2011-11-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article106-110application/pdfhttp://dx.doi.org/10.1590/S0102-86502011000800019Acta Cirurgica Brasileira, v. 26, n. SUPPL. 2, p. 106-110, 2011.0102-86501678-2674http://hdl.handle.net/11449/7279210.1590/S0102-86502011000800019S0102-865020110008000192-s2.0-805551249172-s2.0-80555124917.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporActa Cirúrgica Brasileira0.9330,395info:eu-repo/semantics/openAccess2024-01-15T06:19:28Zoai:repositorio.unesp.br:11449/72792Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:01:27.715371Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
Características anatômicas da cateterização da uretra e bexiga de camundongos e ratos fêmeas. instrumento essencial na pesquisa pré clínica
title Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
spellingShingle Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
Reis, Leonardo Oliveira
Anatomy
Rats
Rodent diseases
Urinary tract
animal anatomy
animal experiment
bladder
bladder catheterization
cancer research
carcinogenesis
cost benefit analysis
female
mouse
nonhuman
rat
toxicity testing
urethra
urethral catheterization
vesicoureteral reflux
Animals
Female
Medical Illustration
Mice
Models, Animal
Reproducibility of Results
Sex Factors
Urethra
Urinary Bladder
Urinary Catheterization
title_short Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
title_full Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
title_fullStr Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
title_full_unstemmed Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
title_sort Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
author Reis, Leonardo Oliveira
author_facet Reis, Leonardo Oliveira
Sopena, Josep Maria Gaya
Fávaro, Wagner José [UNESP]
Martin, Mireia Castilho
Simão, Antônio Felipe Leite
Reis, Rodolfo Borges dos
Andrade, Murilo Ferreira de
Domenech, Josep Domingo
Cardo, Carlos Cordon
author_role author
author2 Sopena, Josep Maria Gaya
Fávaro, Wagner José [UNESP]
Martin, Mireia Castilho
Simão, Antônio Felipe Leite
Reis, Rodolfo Borges dos
Andrade, Murilo Ferreira de
Domenech, Josep Domingo
Cardo, Carlos Cordon
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Columbia University
Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Reis, Leonardo Oliveira
Sopena, Josep Maria Gaya
Fávaro, Wagner José [UNESP]
Martin, Mireia Castilho
Simão, Antônio Felipe Leite
Reis, Rodolfo Borges dos
Andrade, Murilo Ferreira de
Domenech, Josep Domingo
Cardo, Carlos Cordon
dc.subject.por.fl_str_mv Anatomy
Rats
Rodent diseases
Urinary tract
animal anatomy
animal experiment
bladder
bladder catheterization
cancer research
carcinogenesis
cost benefit analysis
female
mouse
nonhuman
rat
toxicity testing
urethra
urethral catheterization
vesicoureteral reflux
Animals
Female
Medical Illustration
Mice
Models, Animal
Reproducibility of Results
Sex Factors
Urethra
Urinary Bladder
Urinary Catheterization
topic Anatomy
Rats
Rodent diseases
Urinary tract
animal anatomy
animal experiment
bladder
bladder catheterization
cancer research
carcinogenesis
cost benefit analysis
female
mouse
nonhuman
rat
toxicity testing
urethra
urethral catheterization
vesicoureteral reflux
Animals
Female
Medical Illustration
Mice
Models, Animal
Reproducibility of Results
Sex Factors
Urethra
Urinary Bladder
Urinary Catheterization
description PURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.
publishDate 2011
dc.date.none.fl_str_mv 2011-11-10
2014-05-27T11:26:07Z
2014-05-27T11:26:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0102-86502011000800019
Acta Cirurgica Brasileira, v. 26, n. SUPPL. 2, p. 106-110, 2011.
0102-8650
1678-2674
http://hdl.handle.net/11449/72792
10.1590/S0102-86502011000800019
S0102-86502011000800019
2-s2.0-80555124917
2-s2.0-80555124917.pdf
url http://dx.doi.org/10.1590/S0102-86502011000800019
http://hdl.handle.net/11449/72792
identifier_str_mv Acta Cirurgica Brasileira, v. 26, n. SUPPL. 2, p. 106-110, 2011.
0102-8650
1678-2674
10.1590/S0102-86502011000800019
S0102-86502011000800019
2-s2.0-80555124917
2-s2.0-80555124917.pdf
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv Acta Cirúrgica Brasileira
0.933
0,395
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 106-110
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129483067097088

Registros relacionados