Influência do veículo na resposta tecidual e da capacidade de mineralização de um cimento reparador experimental

• Autor(a) principal: Sales, Luciana Solera [UNESP]
• Data de Publicação: 2016
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/155280; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-05-02/000881398.pdf
• topic: Teste de materiais; Cimentos dentários; Materiais dentários; Materials Testing

The objective of this study was to evaluate the tissue response and mineralization ability of an experimental repair cement (CER) using water or resin as vehicles compared to the MTA Angelus cement. Thirty rats were used and all animals received four individual polyethylene tubes containing three of the cements to be tested and one empty tube as control. The evaluation times were 07, 15, 30, 60 and 90 days. After each period, six animals from each group were killed and the polyethylene tubes with tissue that surrounds were removed, fixed in glycol methacrylate and processed for histologycal analysis, embedded in glycol methacrylate and staining with hematoxylin and eosin, von Kossa and without staining for analysis with polarized light. The evaluation criterion was 0: no or few cells and no reaction; 1: less than 25 cells and mild reaction; 2: between 25 and 125 cells and moderate reaction; 3: 125 or more cells and severe reaction. fibrous capsule was considered thin when <150μm thick when> 150μm. mineralization presence was recorded as present or absent. The results were analyzed statistically by ANOVA and Kruskal-Wallis tests. The control on 07 and 15 days, showed a moderate inflammatory response at 30, 60 and 90 days, a mild inflammatory response, no structures birefringent to polarized light and mineralization areas. The specimens containing the tube with MTA, CER Water and CER Resin presented on 07 and 15 days, a moderate inflammatory response with a reduction over time. On 30 days the specimens containing the tube with CER Resin also presented a moderate inflammatory response, as the MTA and CER Water showed a mild inflammatory response. On 60 and 90 days a mild inflammatory response was found in both groups. Structures birefringent polarized light and mineralized areas were found at all times and evaluated in both groups. The results of this study showed that the CER Water and CER Resin were biocompatible and induce mineralization