Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae)
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/232008 |
Resumo: | Hemograms and acute-phase proteins in adult male New Zealand White rabbits that had been experimentally infected orally with sporulated oocysts of Eimeria stiedai were evaluated over a 28-day period. Fifty animals were used, divided into two groups: group A infected with 1 × 10 4 sporulated oocysts of E. stiedai and group B inoculated with distilled water. On the seventh day after infection, the infected animals presented anemia and leukocytosis with neutrophilia and monocytosis. Protein fractionation by means of electrophoresis identified 19 acute-phase proteins with molecular weights ranging from 24 to 238 kD. Ceruloplasmin, transferrin and haptoglobin showed high levels on the seventh day after infection, with gradual increases in their concentrations until the end of the experimental period. Thus, from the data of the present study, E. stiedai is considered to be a pyogenic etiological agent for which the infection level can be monitored through the leukocyte count and serum concentrations of ceruloplasmin, transferrin and haptoglobin, and these can be recommended as complementary tests. |
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Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae)Systemic inflammatory response indicators in rabbits (Oryctolagus cuniculus) experimentally infected with sporulated oocysts of Eimeria stiedai (Apicomplexa: Eimeriidae)Acute-phase proteinsEimeria stiedaiOryctolagus cuniculusHemograms and acute-phase proteins in adult male New Zealand White rabbits that had been experimentally infected orally with sporulated oocysts of Eimeria stiedai were evaluated over a 28-day period. Fifty animals were used, divided into two groups: group A infected with 1 × 10 4 sporulated oocysts of E. stiedai and group B inoculated with distilled water. On the seventh day after infection, the infected animals presented anemia and leukocytosis with neutrophilia and monocytosis. Protein fractionation by means of electrophoresis identified 19 acute-phase proteins with molecular weights ranging from 24 to 238 kD. Ceruloplasmin, transferrin and haptoglobin showed high levels on the seventh day after infection, with gradual increases in their concentrations until the end of the experimental period. Thus, from the data of the present study, E. stiedai is considered to be a pyogenic etiological agent for which the infection level can be monitored through the leukocyte count and serum concentrations of ceruloplasmin, transferrin and haptoglobin, and these can be recommended as complementary tests.School of Veterinary Medicine and Zootechnics Federal University of Tocantins - UFT, BR 153, Km 112, Zona Rural, CP 132, CEP 77804-970, Araguaína - TOPostgraduate Program on Experimental Epidemiology Applied to Zoonoses University of São Paulo - USPPostgraduate Program on Industrial Biotechnology University of São Paulo - USPSchool of Agrarian and Veterinary Sciences São Paulo State University - UNESPSchool of Agrarian and Veterinary Sciences São Paulo State University - UNESPFederal University of Tocantins - UFTUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)da Costa Freitas, Fagner LuizYamamoto, Beatriz Lieda Costa Freitas, Wagner LuizFagliari, Jose Jurandir [UNESP]de Sousa Almeida, KatyaneMachado, Rosangela Zacarias [UNESP]Machado, Celio Raimundo [UNESP]2022-04-29T08:48:40Z2022-04-29T08:48:40Z2011-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article121-126Revista Brasileira de Parasitologia Veterinaria, v. 20, n. 2, p. 121-126, 2011.0103-846Xhttp://hdl.handle.net/11449/2320082-s2.0-79959867399Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporRevista Brasileira de Parasitologia Veterinariainfo:eu-repo/semantics/openAccess2024-06-07T13:01:33Zoai:repositorio.unesp.br:11449/232008Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:41:18.817442Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) Systemic inflammatory response indicators in rabbits (Oryctolagus cuniculus) experimentally infected with sporulated oocysts of Eimeria stiedai (Apicomplexa: Eimeriidae) |
title |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
spellingShingle |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) da Costa Freitas, Fagner Luiz Acute-phase proteins Eimeria stiedai Oryctolagus cuniculus |
title_short |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
title_full |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
title_fullStr |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
title_full_unstemmed |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
title_sort |
Indicadores da resposta inflamatória sistêmica em coelhos (Oryctolagus cuniculus) infectados experimentalmente com oocistos esporulados de Eimeria stiedai (Apicomplexa: Eimeriidae) |
author |
da Costa Freitas, Fagner Luiz |
author_facet |
da Costa Freitas, Fagner Luiz Yamamoto, Beatriz Lie da Costa Freitas, Wagner Luiz Fagliari, Jose Jurandir [UNESP] de Sousa Almeida, Katyane Machado, Rosangela Zacarias [UNESP] Machado, Celio Raimundo [UNESP] |
author_role |
author |
author2 |
Yamamoto, Beatriz Lie da Costa Freitas, Wagner Luiz Fagliari, Jose Jurandir [UNESP] de Sousa Almeida, Katyane Machado, Rosangela Zacarias [UNESP] Machado, Celio Raimundo [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Federal University of Tocantins - UFT Universidade de São Paulo (USP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
da Costa Freitas, Fagner Luiz Yamamoto, Beatriz Lie da Costa Freitas, Wagner Luiz Fagliari, Jose Jurandir [UNESP] de Sousa Almeida, Katyane Machado, Rosangela Zacarias [UNESP] Machado, Celio Raimundo [UNESP] |
dc.subject.por.fl_str_mv |
Acute-phase proteins Eimeria stiedai Oryctolagus cuniculus |
topic |
Acute-phase proteins Eimeria stiedai Oryctolagus cuniculus |
description |
Hemograms and acute-phase proteins in adult male New Zealand White rabbits that had been experimentally infected orally with sporulated oocysts of Eimeria stiedai were evaluated over a 28-day period. Fifty animals were used, divided into two groups: group A infected with 1 × 10 4 sporulated oocysts of E. stiedai and group B inoculated with distilled water. On the seventh day after infection, the infected animals presented anemia and leukocytosis with neutrophilia and monocytosis. Protein fractionation by means of electrophoresis identified 19 acute-phase proteins with molecular weights ranging from 24 to 238 kD. Ceruloplasmin, transferrin and haptoglobin showed high levels on the seventh day after infection, with gradual increases in their concentrations until the end of the experimental period. Thus, from the data of the present study, E. stiedai is considered to be a pyogenic etiological agent for which the infection level can be monitored through the leukocyte count and serum concentrations of ceruloplasmin, transferrin and haptoglobin, and these can be recommended as complementary tests. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-04-01 2022-04-29T08:48:40Z 2022-04-29T08:48:40Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Revista Brasileira de Parasitologia Veterinaria, v. 20, n. 2, p. 121-126, 2011. 0103-846X http://hdl.handle.net/11449/232008 2-s2.0-79959867399 |
identifier_str_mv |
Revista Brasileira de Parasitologia Veterinaria, v. 20, n. 2, p. 121-126, 2011. 0103-846X 2-s2.0-79959867399 |
url |
http://hdl.handle.net/11449/232008 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
Revista Brasileira de Parasitologia Veterinaria |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
121-126 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128401834246144 |