Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?

Detalhes bibliográficos
Autor(a) principal: Toscano, João Henrique Barbosa [UNESP]
Data de Publicação: 2019
Outros Autores: dos Santos, Isabella Barbosa [UNESP], von Haehling, Marei Borsch [UNESP], Giraldelo, Luciana Aparecida, Lopes, Louyse Gabrielli, da Silva, Matheus Henrique, Figueiredo, Amanda [UNESP], Esteves, Sérgio Novita, Chagas, Ana Carolina de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.vpoa.2019.100019
http://hdl.handle.net/11449/221376
Resumo: Morada Nova is a Brazilian hair sheep breed that is well adapted to the country's mainly tropical climate and has good potential for meat and leather production. This breed is reported to be resistant to Haemonchus contortus infection, a highly desired characteristic due to the large impact of this parasite on sheep farming. Therefore, the present study aimed to characterize 287 recently weaned Morada Nova lambs and 123 ewes in relation to their resistance against H. contortus. The animals were dewormed and 15 days later artificially infected with 4000 H. contortus L3 (D0). They were individually monitored by periodic assessment of fecal egg count (FEC), packed cell volume (PCV), and live weight (LW). On D42, the sheep were again dewormed and submitted to a new parasitic challenge, following the same scheme. The animals of each category (lambs and ewes) were ranked according to individual mean FEC values, and classified as resistant (R, 20%), intermediate (I, 60%), or susceptible (S, 20%) to H. contortus infection. At weaning, high FEC were observed in all three phenotypes (P > 0.05). After the artificial infections, there was a significant difference (P < 0.05) among the three lamb phenotypes for the mean FEC (R < I < S), PCV (R > I > S), and LW (R = I > S). The infection levels (FEC) were negatively correlated with PCV (r = -0.66; P < 0.001), and LW (r = -0.30; P < 0.001). Despite this, the lambs were resilient, since more than 88% of these animals maintained the PCV above 24%, even when heavily infected. The importance of selective parasite control before weaning to reduce the negative impact on slaughter weight was evidenced, taking into account the high positive correlation between LW at weaning and final LW (r = 0.73; P < 0.001). The ewes, in turn, were strongly resistant to the parasite. Despite highly significant differences (P < 0.001) for mean FEC between phenotypes (R < I < S), 98% of the ewes maintained FEC below 4000 EPG. Their health was not affected, since PCV and LW did not differ between phenotypes, and these parameters were not significantly correlated with FEC (P > 0.05). With the phenotypic characterization performed here, it is possible to introduce procedures for parasite control in Morada Nova flocks, facilitating the target-selective treatment approach. The results of this study can also support improvement of meat production by the Morada Nova breed.
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spelling Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?Artificial infectionHost resistanceMorada Nova breedResilienceSheep haemonchosisMorada Nova is a Brazilian hair sheep breed that is well adapted to the country's mainly tropical climate and has good potential for meat and leather production. This breed is reported to be resistant to Haemonchus contortus infection, a highly desired characteristic due to the large impact of this parasite on sheep farming. Therefore, the present study aimed to characterize 287 recently weaned Morada Nova lambs and 123 ewes in relation to their resistance against H. contortus. The animals were dewormed and 15 days later artificially infected with 4000 H. contortus L3 (D0). They were individually monitored by periodic assessment of fecal egg count (FEC), packed cell volume (PCV), and live weight (LW). On D42, the sheep were again dewormed and submitted to a new parasitic challenge, following the same scheme. The animals of each category (lambs and ewes) were ranked according to individual mean FEC values, and classified as resistant (R, 20%), intermediate (I, 60%), or susceptible (S, 20%) to H. contortus infection. At weaning, high FEC were observed in all three phenotypes (P > 0.05). After the artificial infections, there was a significant difference (P < 0.05) among the three lamb phenotypes for the mean FEC (R < I < S), PCV (R > I > S), and LW (R = I > S). The infection levels (FEC) were negatively correlated with PCV (r = -0.66; P < 0.001), and LW (r = -0.30; P < 0.001). Despite this, the lambs were resilient, since more than 88% of these animals maintained the PCV above 24%, even when heavily infected. The importance of selective parasite control before weaning to reduce the negative impact on slaughter weight was evidenced, taking into account the high positive correlation between LW at weaning and final LW (r = 0.73; P < 0.001). The ewes, in turn, were strongly resistant to the parasite. Despite highly significant differences (P < 0.001) for mean FEC between phenotypes (R < I < S), 98% of the ewes maintained FEC below 4000 EPG. Their health was not affected, since PCV and LW did not differ between phenotypes, and these parameters were not significantly correlated with FEC (P > 0.05). With the phenotypic characterization performed here, it is possible to introduce procedures for parasite control in Morada Nova flocks, facilitating the target-selective treatment approach. The results of this study can also support improvement of meat production by the Morada Nova breed.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista Júlio de Mesquita Filho Via de Acesso Prof. Paulo Donato Castellane s/nCentro Universitário Central Paulista Rua Miguel Petroni 5111Embrapa Pecuária Sudeste Rodovia Washington Luiz Km 234 s/n Fazenda Canchim PO Box 339Universidade Estadual Paulista Júlio de Mesquita Filho Via de Acesso Prof. Paulo Donato Castellane s/nFAPESP: 2017/01626-1Universidade Estadual Paulista (UNESP)5111Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Toscano, João Henrique Barbosa [UNESP]dos Santos, Isabella Barbosa [UNESP]von Haehling, Marei Borsch [UNESP]Giraldelo, Luciana AparecidaLopes, Louyse Gabriellida Silva, Matheus HenriqueFigueiredo, Amanda [UNESP]Esteves, Sérgio NovitaChagas, Ana Carolina de Souza2022-04-28T19:28:02Z2022-04-28T19:28:02Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.vpoa.2019.100019Veterinary Parasitology: X, v. 2.2590-1389http://hdl.handle.net/11449/22137610.1016/j.vpoa.2019.1000192-s2.0-85073155096Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Parasitology: Xinfo:eu-repo/semantics/openAccess2022-04-28T19:28:03Zoai:repositorio.unesp.br:11449/221376Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:12:58.430311Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
title Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
spellingShingle Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
Toscano, João Henrique Barbosa [UNESP]
Artificial infection
Host resistance
Morada Nova breed
Resilience
Sheep haemonchosis
title_short Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
title_full Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
title_fullStr Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
title_full_unstemmed Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
title_sort Morada Nova sheep breed: Resistant or resilient to Haemonchus contortus infection?
author Toscano, João Henrique Barbosa [UNESP]
author_facet Toscano, João Henrique Barbosa [UNESP]
dos Santos, Isabella Barbosa [UNESP]
von Haehling, Marei Borsch [UNESP]
Giraldelo, Luciana Aparecida
Lopes, Louyse Gabrielli
da Silva, Matheus Henrique
Figueiredo, Amanda [UNESP]
Esteves, Sérgio Novita
Chagas, Ana Carolina de Souza
author_role author
author2 dos Santos, Isabella Barbosa [UNESP]
von Haehling, Marei Borsch [UNESP]
Giraldelo, Luciana Aparecida
Lopes, Louyse Gabrielli
da Silva, Matheus Henrique
Figueiredo, Amanda [UNESP]
Esteves, Sérgio Novita
Chagas, Ana Carolina de Souza
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
5111
Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.author.fl_str_mv Toscano, João Henrique Barbosa [UNESP]
dos Santos, Isabella Barbosa [UNESP]
von Haehling, Marei Borsch [UNESP]
Giraldelo, Luciana Aparecida
Lopes, Louyse Gabrielli
da Silva, Matheus Henrique
Figueiredo, Amanda [UNESP]
Esteves, Sérgio Novita
Chagas, Ana Carolina de Souza
dc.subject.por.fl_str_mv Artificial infection
Host resistance
Morada Nova breed
Resilience
Sheep haemonchosis
topic Artificial infection
Host resistance
Morada Nova breed
Resilience
Sheep haemonchosis
description Morada Nova is a Brazilian hair sheep breed that is well adapted to the country's mainly tropical climate and has good potential for meat and leather production. This breed is reported to be resistant to Haemonchus contortus infection, a highly desired characteristic due to the large impact of this parasite on sheep farming. Therefore, the present study aimed to characterize 287 recently weaned Morada Nova lambs and 123 ewes in relation to their resistance against H. contortus. The animals were dewormed and 15 days later artificially infected with 4000 H. contortus L3 (D0). They were individually monitored by periodic assessment of fecal egg count (FEC), packed cell volume (PCV), and live weight (LW). On D42, the sheep were again dewormed and submitted to a new parasitic challenge, following the same scheme. The animals of each category (lambs and ewes) were ranked according to individual mean FEC values, and classified as resistant (R, 20%), intermediate (I, 60%), or susceptible (S, 20%) to H. contortus infection. At weaning, high FEC were observed in all three phenotypes (P > 0.05). After the artificial infections, there was a significant difference (P < 0.05) among the three lamb phenotypes for the mean FEC (R < I < S), PCV (R > I > S), and LW (R = I > S). The infection levels (FEC) were negatively correlated with PCV (r = -0.66; P < 0.001), and LW (r = -0.30; P < 0.001). Despite this, the lambs were resilient, since more than 88% of these animals maintained the PCV above 24%, even when heavily infected. The importance of selective parasite control before weaning to reduce the negative impact on slaughter weight was evidenced, taking into account the high positive correlation between LW at weaning and final LW (r = 0.73; P < 0.001). The ewes, in turn, were strongly resistant to the parasite. Despite highly significant differences (P < 0.001) for mean FEC between phenotypes (R < I < S), 98% of the ewes maintained FEC below 4000 EPG. Their health was not affected, since PCV and LW did not differ between phenotypes, and these parameters were not significantly correlated with FEC (P > 0.05). With the phenotypic characterization performed here, it is possible to introduce procedures for parasite control in Morada Nova flocks, facilitating the target-selective treatment approach. The results of this study can also support improvement of meat production by the Morada Nova breed.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
2022-04-28T19:28:02Z
2022-04-28T19:28:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.vpoa.2019.100019
Veterinary Parasitology: X, v. 2.
2590-1389
http://hdl.handle.net/11449/221376
10.1016/j.vpoa.2019.100019
2-s2.0-85073155096
url http://dx.doi.org/10.1016/j.vpoa.2019.100019
http://hdl.handle.net/11449/221376
identifier_str_mv Veterinary Parasitology: X, v. 2.
2590-1389
10.1016/j.vpoa.2019.100019
2-s2.0-85073155096
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Veterinary Parasitology: X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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