The effects of environmental enrichment on biochemical and metric parameters of aged rats
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.seer.ufu.br/index.php/biosciencejournal/article/view/26803 http://hdl.handle.net/11449/129037 |
Resumo: | The enriched environment (EE) is a promoter of physical activity, by its characteristics such as ample room for movement and exploration, presence of wheels, tunnels and toys. The maintenance of animals in enriched environment can bring a range of benefits, but the majority of the researches investigate cognitive parameters and changes related to the nervous system. The aim of this study was to examine the effects of the maintenance of aged rats in enriched cages on biochemical and metric parameters. Wistar rats were randomly distributed (n=6) into two groups during 6 weeks: control (C) in a conventional cage and enriched environment (EE). The body mass were recorded weekly and the body length at the end of the study. After euthanasia, blood was collected for analysis of glucose, triglycerides and the brain was collected for analysis of mass. The EE group had higher brain mass and lower gain of body weight compared to control group. The control group animals had normal values of blood glucose and triglyceride levels, and the maintenance in an EE did not promote changes in these parameters. Therefore, it can be concluded that the EE group increases brain mass and reduces the gain of body weight without changing the blood glucose and triglycerides in aged animals. |
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The effects of environmental enrichment on biochemical and metric parameters of aged ratsEfeitos do ambiente enriquecido em parametros bioquímicos e métricos de ratos idososEnriched environmentPhysical activityObesityBrain massAmbiente enriquecidoAtividade físicaObesidadeMassa encefálicaThe enriched environment (EE) is a promoter of physical activity, by its characteristics such as ample room for movement and exploration, presence of wheels, tunnels and toys. The maintenance of animals in enriched environment can bring a range of benefits, but the majority of the researches investigate cognitive parameters and changes related to the nervous system. The aim of this study was to examine the effects of the maintenance of aged rats in enriched cages on biochemical and metric parameters. Wistar rats were randomly distributed (n=6) into two groups during 6 weeks: control (C) in a conventional cage and enriched environment (EE). The body mass were recorded weekly and the body length at the end of the study. After euthanasia, blood was collected for analysis of glucose, triglycerides and the brain was collected for analysis of mass. The EE group had higher brain mass and lower gain of body weight compared to control group. The control group animals had normal values of blood glucose and triglyceride levels, and the maintenance in an EE did not promote changes in these parameters. Therefore, it can be concluded that the EE group increases brain mass and reduces the gain of body weight without changing the blood glucose and triglycerides in aged animals.O ambiente enriquecido (AE) pode ser considerado como promotor de atividade física, pelas suas características como um amplo espaço para deslocamento e exploração, a presença de rodas de atividade, túneis e brinquedos. A manutenção de animais em ambiente enriquecido pode proporcionar uma série de benefícios, mas grande parte dos estudos tem focado a investigação de parâmetros cognitivas e alterações relacionadas ao sistema nervoso. O objetivo deste estudo foi examinar os efeitos da manutenção de ratos idosos em gaiolas enriquecidas sobre parâmetros bioquímicos e métricas. Ratos Wistar foram distribuídos aleatoriamente ( n = 6) em dois grupos durante 6 semanas: controle (C) mantido em gaiola convencional e ambiente enriquecido (AE) . A massa corporal foi registrada semanalmente e o comprimento corporal ao final do estudo. Após a eutanásia, amostras de sangue foram coletadas para análise de glicose e triglicérides e o encéfalo foi coletado para registro da massa. O grupo AE apresentou maior massa encefálica e menor ganho de peso corporal, em comparação ao grupo controle. Os animais do grupo controle apresentaram valores normais de glicose e triglicerídeos no sangue e a manutenção no AE não promoveu alterações nestes parâmetros. Portanto, pode ser concluído que a manutenção no AE aumenta a massa encefálica e reduz o ganho de peso corporal sem alterar a glicose e triglicerídeos no sangue de animais idosos.Universidade Estadual Paulista, Departamento de Eduação Física, Instituto de Biociências de Rio ClaroUniv Federal UberlandiaCentro Universitário Católico “Auxilium” UnisalesianoUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Vieira, Thiago AparecidoCarvalho, Rodrigo Leal de PaivaFerreira, Sarah CristinaOliveira, Ana Paula deModesto Junior, OlayrAssis, Welton Ferreira de [UNESP]Leme, José Alexandre Curiacos de Almeida [UNESP]2015-10-21T20:15:03Z2015-10-21T20:15:03Z2015-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article982-987application/pdfhttp://www.seer.ufu.br/index.php/biosciencejournal/article/view/26803Bioscience Journal. Uberlandia: Univ Federal Uberlandia, v. 31, n. 3, p. 982-987, 2015.1981-3163http://hdl.handle.net/11449/12903710.14393/BJ-v31n3a2015-26803WOS:000356611400037WOS000356611400037.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBioscience Journal0.404info:eu-repo/semantics/openAccess2023-12-18T06:15:56Zoai:repositorio.unesp.br:11449/129037Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:38:15.094278Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The effects of environmental enrichment on biochemical and metric parameters of aged rats Efeitos do ambiente enriquecido em parametros bioquímicos e métricos de ratos idosos |
title |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
spellingShingle |
The effects of environmental enrichment on biochemical and metric parameters of aged rats Vieira, Thiago Aparecido Enriched environment Physical activity Obesity Brain mass Ambiente enriquecido Atividade física Obesidade Massa encefálica |
title_short |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
title_full |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
title_fullStr |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
title_full_unstemmed |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
title_sort |
The effects of environmental enrichment on biochemical and metric parameters of aged rats |
author |
Vieira, Thiago Aparecido |
author_facet |
Vieira, Thiago Aparecido Carvalho, Rodrigo Leal de Paiva Ferreira, Sarah Cristina Oliveira, Ana Paula de Modesto Junior, Olayr Assis, Welton Ferreira de [UNESP] Leme, José Alexandre Curiacos de Almeida [UNESP] |
author_role |
author |
author2 |
Carvalho, Rodrigo Leal de Paiva Ferreira, Sarah Cristina Oliveira, Ana Paula de Modesto Junior, Olayr Assis, Welton Ferreira de [UNESP] Leme, José Alexandre Curiacos de Almeida [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Centro Universitário Católico “Auxilium” Unisalesiano Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Vieira, Thiago Aparecido Carvalho, Rodrigo Leal de Paiva Ferreira, Sarah Cristina Oliveira, Ana Paula de Modesto Junior, Olayr Assis, Welton Ferreira de [UNESP] Leme, José Alexandre Curiacos de Almeida [UNESP] |
dc.subject.por.fl_str_mv |
Enriched environment Physical activity Obesity Brain mass Ambiente enriquecido Atividade física Obesidade Massa encefálica |
topic |
Enriched environment Physical activity Obesity Brain mass Ambiente enriquecido Atividade física Obesidade Massa encefálica |
description |
The enriched environment (EE) is a promoter of physical activity, by its characteristics such as ample room for movement and exploration, presence of wheels, tunnels and toys. The maintenance of animals in enriched environment can bring a range of benefits, but the majority of the researches investigate cognitive parameters and changes related to the nervous system. The aim of this study was to examine the effects of the maintenance of aged rats in enriched cages on biochemical and metric parameters. Wistar rats were randomly distributed (n=6) into two groups during 6 weeks: control (C) in a conventional cage and enriched environment (EE). The body mass were recorded weekly and the body length at the end of the study. After euthanasia, blood was collected for analysis of glucose, triglycerides and the brain was collected for analysis of mass. The EE group had higher brain mass and lower gain of body weight compared to control group. The control group animals had normal values of blood glucose and triglyceride levels, and the maintenance in an EE did not promote changes in these parameters. Therefore, it can be concluded that the EE group increases brain mass and reduces the gain of body weight without changing the blood glucose and triglycerides in aged animals. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-10-21T20:15:03Z 2015-10-21T20:15:03Z 2015-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.seer.ufu.br/index.php/biosciencejournal/article/view/26803 Bioscience Journal. Uberlandia: Univ Federal Uberlandia, v. 31, n. 3, p. 982-987, 2015. 1981-3163 http://hdl.handle.net/11449/129037 10.14393/BJ-v31n3a2015-26803 WOS:000356611400037 WOS000356611400037.pdf |
url |
http://www.seer.ufu.br/index.php/biosciencejournal/article/view/26803 http://hdl.handle.net/11449/129037 |
identifier_str_mv |
Bioscience Journal. Uberlandia: Univ Federal Uberlandia, v. 31, n. 3, p. 982-987, 2015. 1981-3163 10.14393/BJ-v31n3a2015-26803 WOS:000356611400037 WOS000356611400037.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Bioscience Journal 0.404 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
982-987 application/pdf |
dc.publisher.none.fl_str_mv |
Univ Federal Uberlandia |
publisher.none.fl_str_mv |
Univ Federal Uberlandia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129230302609408 |