Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs

Detalhes bibliográficos
Autor(a) principal: Aquino, Lúcia Padilha Cury Thomaz de [UNESP]
Data de Publicação: 1999
Outros Autores: Machado, Rosangela Zacarias [UNESP], Alessi, Antônio Carlos [UNESP], Marques, Luiz Carlos [UNESP], Castro, Márcio Botelho de [UNESP], Malheiros, Euclides Braga [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0074-02761999000200025
http://hdl.handle.net/11449/2965
Resumo: This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia
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spelling Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogsTrypanosoma evansiDogbiometryELISAinmunofluorescent antibody testclinical featuresThis research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemiaUnespUnespInstituto Oswaldo Cruz, Ministério da SaúdeUniversidade Estadual Paulista (Unesp)Aquino, Lúcia Padilha Cury Thomaz de [UNESP]Machado, Rosangela Zacarias [UNESP]Alessi, Antônio Carlos [UNESP]Marques, Luiz Carlos [UNESP]Castro, Márcio Botelho de [UNESP]Malheiros, Euclides Braga [UNESP]2014-05-20T13:15:58Z2014-05-20T13:15:58Z1999-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article255-260application/pdfhttp://dx.doi.org/10.1590/S0074-02761999000200025Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 94, n. 2, p. 255-260, 1999.0074-0276http://hdl.handle.net/11449/296510.1590/S0074-02761999000200025S0074-02761999000200025S0074-02761999000200025.pdf325499061245183632815384740119794726596193949022SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMemórias do Instituto Oswaldo Cruz2.8331,172info:eu-repo/semantics/openAccess2024-06-07T13:02:26Zoai:repositorio.unesp.br:11449/2965Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:49:35.707479Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
title Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
spellingShingle Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
Aquino, Lúcia Padilha Cury Thomaz de [UNESP]
Trypanosoma evansi
Dog
biometry
ELISA
inmunofluorescent antibody test
clinical features
title_short Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
title_full Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
title_fullStr Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
title_full_unstemmed Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
title_sort Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
author Aquino, Lúcia Padilha Cury Thomaz de [UNESP]
author_facet Aquino, Lúcia Padilha Cury Thomaz de [UNESP]
Machado, Rosangela Zacarias [UNESP]
Alessi, Antônio Carlos [UNESP]
Marques, Luiz Carlos [UNESP]
Castro, Márcio Botelho de [UNESP]
Malheiros, Euclides Braga [UNESP]
author_role author
author2 Machado, Rosangela Zacarias [UNESP]
Alessi, Antônio Carlos [UNESP]
Marques, Luiz Carlos [UNESP]
Castro, Márcio Botelho de [UNESP]
Malheiros, Euclides Braga [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Aquino, Lúcia Padilha Cury Thomaz de [UNESP]
Machado, Rosangela Zacarias [UNESP]
Alessi, Antônio Carlos [UNESP]
Marques, Luiz Carlos [UNESP]
Castro, Márcio Botelho de [UNESP]
Malheiros, Euclides Braga [UNESP]
dc.subject.por.fl_str_mv Trypanosoma evansi
Dog
biometry
ELISA
inmunofluorescent antibody test
clinical features
topic Trypanosoma evansi
Dog
biometry
ELISA
inmunofluorescent antibody test
clinical features
description This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia
publishDate 1999
dc.date.none.fl_str_mv 1999-03-01
2014-05-20T13:15:58Z
2014-05-20T13:15:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0074-02761999000200025
Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 94, n. 2, p. 255-260, 1999.
0074-0276
http://hdl.handle.net/11449/2965
10.1590/S0074-02761999000200025
S0074-02761999000200025
S0074-02761999000200025.pdf
3254990612451836
3281538474011979
4726596193949022
url http://dx.doi.org/10.1590/S0074-02761999000200025
http://hdl.handle.net/11449/2965
identifier_str_mv Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 94, n. 2, p. 255-260, 1999.
0074-0276
10.1590/S0074-02761999000200025
S0074-02761999000200025
S0074-02761999000200025.pdf
3254990612451836
3281538474011979
4726596193949022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Memórias do Instituto Oswaldo Cruz
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 255-260
application/pdf
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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