Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/0103-8478cr20151621 http://hdl.handle.net/11449/157668 |
Resumo: | ABSTRACT: The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time. |
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Repositório Institucional da UNESP |
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Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administrationIndice biespectral em bezerros submetidos à infusão contínua de propofol associado ao fentanilcalvesruminantsbalanced anesthesiaanesthetic monitoringbezerrosruminantesanestesia balanceadamonitoração anestésicaABSTRACT: The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time.RESUMO: O estudo teve por objetivo avaliar o índice biespectral (BIS) durante a infusão contínua de propofol associado ou não ao fentanil em bezerros. Foram utilizados oito animais machos entre seis e doze meses de idade, holandeses, com massa corporal média de 123±18kg. Todos os animais participaram de ambos os grupos, respeitando-se sempre um intervalo mínimo de uma semana entre uma anestesia e outra, sendo aleatoriamente distribuídos entre os grupos. A anestesia nos bezerros foi induzida com propofol na dose de 5mg kg-1; intravenoso (IV), grupo controle (GP) ou propofol 4mg kg-1 associado ao fentanil 0,001mg kg-1; IV, grupo fentanil (GF) e posicionados em decúbito lateral direito, onde permaneceram respirando espontaneamente ar ambiente. Ato contínuo, a manutenção anestésica foi realizada pela infusão contínua de propofol na taxa de 0,6mg kg-1 min-1; IV GP, associado ou não à infusão de fentanil 0.001mg kg-1 hora-1 GF. A mensuração das variáveis do BIS, índice de qualidade de sinal (IQS) eletromiografia (EMG), frequência cardíaca (FC), frequência respiratória (f) e dióxido de carbono ao final da expiração (ETCO2) foram avaliadas antes da indução anestésica no momento basal (MB), e 15, 30, 45 e 60 minutos após o início da infusão contínua dos fármacos (M15, M30, M45 e M60, respectivamente); o tempo de recuperação também foi avaliado. Não foram observadas diferenças significativas entre os grupos nas variáveis do BIS e o tempo de recuperação foi maior no GF. A co-administração das infusões de propofol e fentanil, nas doses utilizadas nesse estudo, não alterou os valores do BIS em bezerros, porém, prolongou o tempo de recuperação.Universidade Estadual Paulista Faculdade de Medicina Veterinária e ZootecniaUniversidade Estadual Paulista Faculdade de Medicina VeterináriaUniversidade Federal de Mato Grosso do Sul Faculdade de Medicina Veterinária e ZootecniaUniversidade Estadual Paulista Faculdade de Medicina Veterinária e ZootecniaUniversidade Estadual Paulista Faculdade de Medicina VeterináriaUniversidade Federal de Santa MariaUniversidade Estadual Paulista (Unesp)Universidade Federal de Mato Grosso do Sul Faculdade de Medicina Veterinária e ZootecniaDeschk, MauricioTrein, Thomas AlexanderWagatsuma, Juliana TessáliaSilva, Guilherme Lopes DaAraújo, Marcelo Augusto DeGames, Bruna De Moraes MartinsAlcindo, Jefferson FilgueiraRodrigues, Celso AntônioSantos, Paulo Sergio Patto Dos2018-11-12T17:26:24Z2018-11-12T17:26:24Z2017-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article-application/pdfhttp://dx.doi.org/10.1590/0103-8478cr20151621Ciência Rural. Universidade Federal de Santa Maria, v. 47, n. 11, p. -, 2017.0103-8478http://hdl.handle.net/11449/15766810.1590/0103-8478cr20151621S0103-84782017001100602S0103-84782017001100602.pdf53319389628966640000-0002-8535-5569SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Rural0,337info:eu-repo/semantics/openAccess2023-10-14T06:06:29Zoai:repositorio.unesp.br:11449/157668Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:53:24.758186Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration Indice biespectral em bezerros submetidos à infusão contínua de propofol associado ao fentanil |
title |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
spellingShingle |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration Deschk, Mauricio calves ruminants balanced anesthesia anesthetic monitoring bezerros ruminantes anestesia balanceada monitoração anestésica |
title_short |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
title_full |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
title_fullStr |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
title_full_unstemmed |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
title_sort |
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration |
author |
Deschk, Mauricio |
author_facet |
Deschk, Mauricio Trein, Thomas Alexander Wagatsuma, Juliana Tessália Silva, Guilherme Lopes Da Araújo, Marcelo Augusto De Games, Bruna De Moraes Martins Alcindo, Jefferson Filgueira Rodrigues, Celso Antônio Santos, Paulo Sergio Patto Dos |
author_role |
author |
author2 |
Trein, Thomas Alexander Wagatsuma, Juliana Tessália Silva, Guilherme Lopes Da Araújo, Marcelo Augusto De Games, Bruna De Moraes Martins Alcindo, Jefferson Filgueira Rodrigues, Celso Antônio Santos, Paulo Sergio Patto Dos |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal de Mato Grosso do Sul Faculdade de Medicina Veterinária e Zootecnia |
dc.contributor.author.fl_str_mv |
Deschk, Mauricio Trein, Thomas Alexander Wagatsuma, Juliana Tessália Silva, Guilherme Lopes Da Araújo, Marcelo Augusto De Games, Bruna De Moraes Martins Alcindo, Jefferson Filgueira Rodrigues, Celso Antônio Santos, Paulo Sergio Patto Dos |
dc.subject.por.fl_str_mv |
calves ruminants balanced anesthesia anesthetic monitoring bezerros ruminantes anestesia balanceada monitoração anestésica |
topic |
calves ruminants balanced anesthesia anesthetic monitoring bezerros ruminantes anestesia balanceada monitoração anestésica |
description |
ABSTRACT: The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-11-01 2018-11-12T17:26:24Z 2018-11-12T17:26:24Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/0103-8478cr20151621 Ciência Rural. Universidade Federal de Santa Maria, v. 47, n. 11, p. -, 2017. 0103-8478 http://hdl.handle.net/11449/157668 10.1590/0103-8478cr20151621 S0103-84782017001100602 S0103-84782017001100602.pdf 5331938962896664 0000-0002-8535-5569 |
url |
http://dx.doi.org/10.1590/0103-8478cr20151621 http://hdl.handle.net/11449/157668 |
identifier_str_mv |
Ciência Rural. Universidade Federal de Santa Maria, v. 47, n. 11, p. -, 2017. 0103-8478 10.1590/0103-8478cr20151621 S0103-84782017001100602 S0103-84782017001100602.pdf 5331938962896664 0000-0002-8535-5569 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciência Rural 0,337 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
- application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128431203811328 |