Congenital persistent infection with bovine viral diarrhea virus not observed in piglets

• Autor(a) principal: Gomes, Felipe S. [UNESP]
• Data de Publicação: 2019
• Outros Autores: Mechler-Dreibi, Marina L. [UNESP], Gatto, Igor R. H. [UNESP], Storino, Gabriel Y. [UNESP], Pires, Felipe F.B. [UNESP], Xavier, Eduarda B. [UNESP], Samara, Samir I. [UNESP], De Oliveira, Luis Guilherme [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/198110

This study was designed to determine whether congenital persistent infection occurs in piglets from gilts experimentally inoculated with bovine viral diarrhea virus type 2 (BVDV-2). Six pregnant gilts were divided into 2 groups, infected (n = 4), and control (n = 2). The gilts were inoculated at 45 days gestation. Piglets were assessed for 35 days following birth with nasal swab and blood sample collections every 72 hours. Reverse transcriptase-polymerase chain reaction (RT-PCR) tests were performed for direct diagnosis of virus in blood and nasal swabs, and virus neutralization was used for antibody detection. Transplacental transmission of BVDV-2 did not occur. Piglets were born free of the virus and did not shed BVDV during the experimental period.