Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1678-7757201302129 http://hdl.handle.net/11449/75900 |
Resumo: | The purpose of this study was to evaluate the effectiveness of glycolic propolis (PRO) and ginger (GIN) extracts, calcium hydroxide (CH), chlorhexidine (CLX) gel and their combinations as ICMs (ICMs) against Candida albicans, Enterococcus faecalis, Escherichia coli and endotoxins in root canals. Material and Methods: After 28 days of contamination with microorganisms, the canals were instrumented and then divided according to the ICM: CH+saline; CLX, CH+CLX, PRO, PRO+CH; GIN; GIN+CH; saline. The antimicrobial activity and quantification of endotoxins by the chromogenic test of Limulus amebocyte lysate were evaluated after contamination and instrumentation at 14 days of ICM application and 7 days after ICM removal. Results and Conclusion: After analysis of results and application ofthe Kruskal-Wallis and Dunn statistical tests at 5% significance level, it was concluded that all ICMs were able to eliminate the microorganisms in the root canals and reduce their amount of endotoxins; however, CH was more effective in neutralizing endotoxins and less effective against C. albicans and E. faecalis, requiring the use of medication combinations to obtain higher success. |
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Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canalsCalcium hydroxideCandida albicansEnterococcus faecalisEscherichia coli. endotoxinsPropolisZingiber officinalebiomedical and dental materialscalcium hydroxidechlorhexidinedisinfectant agentendotoxinpropolischemistrydrug effectendodonticsEscherichia coligingerhumanmicrobiologynonparametric testtimetooth pulpCalcium HydroxideChlorhexidineDental Pulp CavityDisinfectantsEndotoxinsGingerHumansRoot Canal IrrigantsRoot Canal PreparationStatistics, NonparametricTime FactorsThe purpose of this study was to evaluate the effectiveness of glycolic propolis (PRO) and ginger (GIN) extracts, calcium hydroxide (CH), chlorhexidine (CLX) gel and their combinations as ICMs (ICMs) against Candida albicans, Enterococcus faecalis, Escherichia coli and endotoxins in root canals. Material and Methods: After 28 days of contamination with microorganisms, the canals were instrumented and then divided according to the ICM: CH+saline; CLX, CH+CLX, PRO, PRO+CH; GIN; GIN+CH; saline. The antimicrobial activity and quantification of endotoxins by the chromogenic test of Limulus amebocyte lysate were evaluated after contamination and instrumentation at 14 days of ICM application and 7 days after ICM removal. Results and Conclusion: After analysis of results and application ofthe Kruskal-Wallis and Dunn statistical tests at 5% significance level, it was concluded that all ICMs were able to eliminate the microorganisms in the root canals and reduce their amount of endotoxins; however, CH was more effective in neutralizing endotoxins and less effective against C. albicans and E. faecalis, requiring the use of medication combinations to obtain higher success.Department of Restorative Dentistry UNESP-Univ Estadual Paulista, São José dos Campos, SPDepartment of Biosciences and Oral Diagnosis UNESP-Univ Estadual Paulista, São José dos Campos, SPDepartment of Oral Diagnosis and Biosciences UNESP-Univ Estadual Paulista, São José dos Campos, SPDepartment of Restorative Dentistry UNESP-Univ Estadual Paulista, São José dos Campos, SPDepartment of Biosciences and Oral Diagnosis UNESP-Univ Estadual Paulista, São José dos Campos, SPDepartment of Oral Diagnosis and Biosciences UNESP-Univ Estadual Paulista, São José dos Campos, SPUniversidade Estadual Paulista (Unesp)Maekawa, Lilian Eiko [UNESP]Valera, Marcia Carneiro [UNESP]Oliveira, Luciane Dias de [UNESP]Carvalho, Cláudio Antonio Talge [UNESP]Camargo, Carlos Henrique Ribeiro [UNESP]Jorge, Antonio Olavo Cardoso [UNESP]2014-05-27T11:29:54Z2014-05-27T11:29:54Z2013-07-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article25-31application/pdfhttp://dx.doi.org/10.1590/1678-7757201302129Journal of Applied Oral Science, v. 21, n. 1, p. 25-31, 2013.1678-77571678-7765http://hdl.handle.net/11449/7590010.1590/1678-7757201302129S1678-7757201302129WOS:0003171953000052-s2.0-848786458082-s2.0-84878645808.pdf4716676611330311005356715362356993046001665831000000-0003-0987-5594Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-11-17T06:16:01Zoai:repositorio.unesp.br:11449/75900Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:59:51.464405Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
title |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
spellingShingle |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals Maekawa, Lilian Eiko [UNESP] Calcium hydroxide Candida albicans Enterococcus faecalis Escherichia coli. endotoxins Propolis Zingiber officinale biomedical and dental materials calcium hydroxide chlorhexidine disinfectant agent endotoxin propolis chemistry drug effect endodontics Escherichia coli ginger human microbiology nonparametric test time tooth pulp Calcium Hydroxide Chlorhexidine Dental Pulp Cavity Disinfectants Endotoxins Ginger Humans Root Canal Irrigants Root Canal Preparation Statistics, Nonparametric Time Factors |
title_short |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
title_full |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
title_fullStr |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
title_full_unstemmed |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
title_sort |
Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals |
author |
Maekawa, Lilian Eiko [UNESP] |
author_facet |
Maekawa, Lilian Eiko [UNESP] Valera, Marcia Carneiro [UNESP] Oliveira, Luciane Dias de [UNESP] Carvalho, Cláudio Antonio Talge [UNESP] Camargo, Carlos Henrique Ribeiro [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
author_role |
author |
author2 |
Valera, Marcia Carneiro [UNESP] Oliveira, Luciane Dias de [UNESP] Carvalho, Cláudio Antonio Talge [UNESP] Camargo, Carlos Henrique Ribeiro [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Maekawa, Lilian Eiko [UNESP] Valera, Marcia Carneiro [UNESP] Oliveira, Luciane Dias de [UNESP] Carvalho, Cláudio Antonio Talge [UNESP] Camargo, Carlos Henrique Ribeiro [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
dc.subject.por.fl_str_mv |
Calcium hydroxide Candida albicans Enterococcus faecalis Escherichia coli. endotoxins Propolis Zingiber officinale biomedical and dental materials calcium hydroxide chlorhexidine disinfectant agent endotoxin propolis chemistry drug effect endodontics Escherichia coli ginger human microbiology nonparametric test time tooth pulp Calcium Hydroxide Chlorhexidine Dental Pulp Cavity Disinfectants Endotoxins Ginger Humans Root Canal Irrigants Root Canal Preparation Statistics, Nonparametric Time Factors |
topic |
Calcium hydroxide Candida albicans Enterococcus faecalis Escherichia coli. endotoxins Propolis Zingiber officinale biomedical and dental materials calcium hydroxide chlorhexidine disinfectant agent endotoxin propolis chemistry drug effect endodontics Escherichia coli ginger human microbiology nonparametric test time tooth pulp Calcium Hydroxide Chlorhexidine Dental Pulp Cavity Disinfectants Endotoxins Ginger Humans Root Canal Irrigants Root Canal Preparation Statistics, Nonparametric Time Factors |
description |
The purpose of this study was to evaluate the effectiveness of glycolic propolis (PRO) and ginger (GIN) extracts, calcium hydroxide (CH), chlorhexidine (CLX) gel and their combinations as ICMs (ICMs) against Candida albicans, Enterococcus faecalis, Escherichia coli and endotoxins in root canals. Material and Methods: After 28 days of contamination with microorganisms, the canals were instrumented and then divided according to the ICM: CH+saline; CLX, CH+CLX, PRO, PRO+CH; GIN; GIN+CH; saline. The antimicrobial activity and quantification of endotoxins by the chromogenic test of Limulus amebocyte lysate were evaluated after contamination and instrumentation at 14 days of ICM application and 7 days after ICM removal. Results and Conclusion: After analysis of results and application ofthe Kruskal-Wallis and Dunn statistical tests at 5% significance level, it was concluded that all ICMs were able to eliminate the microorganisms in the root canals and reduce their amount of endotoxins; however, CH was more effective in neutralizing endotoxins and less effective against C. albicans and E. faecalis, requiring the use of medication combinations to obtain higher success. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-02 2014-05-27T11:29:54Z 2014-05-27T11:29:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-7757201302129 Journal of Applied Oral Science, v. 21, n. 1, p. 25-31, 2013. 1678-7757 1678-7765 http://hdl.handle.net/11449/75900 10.1590/1678-7757201302129 S1678-7757201302129 WOS:000317195300005 2-s2.0-84878645808 2-s2.0-84878645808.pdf 4716676611330311 0053567153623569 9304600166583100 0000-0003-0987-5594 |
url |
http://dx.doi.org/10.1590/1678-7757201302129 http://hdl.handle.net/11449/75900 |
identifier_str_mv |
Journal of Applied Oral Science, v. 21, n. 1, p. 25-31, 2013. 1678-7757 1678-7765 10.1590/1678-7757201302129 S1678-7757201302129 WOS:000317195300005 2-s2.0-84878645808 2-s2.0-84878645808.pdf 4716676611330311 0053567153623569 9304600166583100 0000-0003-0987-5594 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science 1.709 0,645 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
25-31 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128882650382336 |