Blood pressure and kidney size in term newborns with intrauterine growth restriction

Detalhes bibliográficos
Autor(a) principal: Matsuoka, Oscar Tadashi [UNESP]
Data de Publicação: 2007
Outros Autores: Shibao, Simone [UNESP], Leone, Cléa Rodrigues [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1516-31802007000200004
http://hdl.handle.net/11449/211704
Resumo: CONTEXT AND OBJECTIVE: Low birth weight is associated with higher blood pressure in childhood and adulthood. The aim of this study was to investigate the influence of intrauterine growth restriction (IUGR) on newborn systolic blood pressure (SBP). DESIGN AND SETTING: Prospective comparative study at Neonatal and Intensive in Clinical Pediatrics Division, Maternity Hospital in Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo. METHODS: 35 newborns with IUGR and 35 without IUGR were compared. Healthy term newborns without malformations, with Apgar score at fifth minute > 6 were included. Birth weight, kidney weight/birth weight ratio, kidney weight (ultrasound scan), plasma renin activity (PRA) and SBP evolution were analyzed during the first month of life (on 1st, 3rd, 7th and 30th days). RESULTS: SBP evolution, kidney weight/birth weight ratio and PRA did not differ between the two groups. In newborns with IUGR, SBP presented positive correlations with birth weight (r = 0.387 p = 0.026) and BMI (r = 0.412 p = 0.017) on the 7th day of life. Positive correlations with birth weight (r = 0.440 p = 0.01) and birth length (r = 0.386 p = 0.026) were also seen on the 30th day. There was an inverse correlation on the 7th day between SBP and kidney weight/birth weight ratio (r = -0.420 p = 0.014), but this did not persist to the end of the month. CONCLUSIONS: IUGR seems not to have any influence on SBP, PRA or kidney weight among term newborns during their first month of life.
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spelling Blood pressure and kidney size in term newborns with intrauterine growth restrictionPressão arterial e tamanho renal em recém-nascidos no termo com restrição de crescimento intra-uterinoBlood pressureFetal growth retardationNewborn infantKidneyReninPressão arterialRetardo do crescimento fetalRecém-nascidoRimReninaCONTEXT AND OBJECTIVE: Low birth weight is associated with higher blood pressure in childhood and adulthood. The aim of this study was to investigate the influence of intrauterine growth restriction (IUGR) on newborn systolic blood pressure (SBP). DESIGN AND SETTING: Prospective comparative study at Neonatal and Intensive in Clinical Pediatrics Division, Maternity Hospital in Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo. METHODS: 35 newborns with IUGR and 35 without IUGR were compared. Healthy term newborns without malformations, with Apgar score at fifth minute > 6 were included. Birth weight, kidney weight/birth weight ratio, kidney weight (ultrasound scan), plasma renin activity (PRA) and SBP evolution were analyzed during the first month of life (on 1st, 3rd, 7th and 30th days). RESULTS: SBP evolution, kidney weight/birth weight ratio and PRA did not differ between the two groups. In newborns with IUGR, SBP presented positive correlations with birth weight (r = 0.387 p = 0.026) and BMI (r = 0.412 p = 0.017) on the 7th day of life. Positive correlations with birth weight (r = 0.440 p = 0.01) and birth length (r = 0.386 p = 0.026) were also seen on the 30th day. There was an inverse correlation on the 7th day between SBP and kidney weight/birth weight ratio (r = -0.420 p = 0.014), but this did not persist to the end of the month. CONCLUSIONS: IUGR seems not to have any influence on SBP, PRA or kidney weight among term newborns during their first month of life.CONTEXTO E OBJETIVO: O baixo peso ao nascimento está associado à pressão arterial mais elevada na criança e no adulto. O objetivo foi avaliar a influência do retardo do crescimento intra-uterino (RCIU) na pressão arterial sistólica de recém-nascidos (PAS). TIPO DE ESTUDO E LOCAL: Estudo prospectivo, realizado no berçário anexo à maternidade, Instituto da Criança, Hospital das Clínicas da Universidade de São Paulo. MÉTODOS: 35 recém-nascidos (RN) com RCIU e 35 RN sem RCIU foram avaliados em um estudo prospectivo. Os critérios de inclusão foram: recém-nascidos no termo, saudáveis, sem malformações e índice de Apgar de quinto minuto > 6. Parâmetros antropométricos (peso ao nascimento, relação comprimento renal/peso ao nascimento), dimensões renais (pela ultra-sonografia), dosagem da atividade da renina plasmática (ARP) e a evolução da PAS foram analisadas durante o primeiro mês de vida (no 1º, 3º, 7º e 30º dias de vida). RESULTADOS: A evolução da PAS, relação peso renal/peso ao nascimento e ARP não apresentaram diferença entre os dois grupos. Em recém-nascidos com CIUR, a correlação entre PAS e PN (r = 0,387 p = 0,026) e IMC (r = 0,412 p = 0,017) foi positiva no 7º dia de vida. No 30º dia de vida, a correlação com PN (r = 0,440 p = 0,01) e comprimento ao nascimento (r = 0,386 p = 0,026) também foi positiva. Houve correlação negativa entre a PAS do 7º dia e a relação peso do rim/peso ao nascimento (r = - 0,420 p = 0,014), porém, esta correlação não persistiu ao longo do primeiro mês de vida. CONCLUSÕES: RCIU parece não influenciar a PAS, a atividade de renina plasmática ou o peso renal em recém-nascidos no termo durante o primeiro mês de vida.Universidade Estadual Paulista, Hospital of the São PauloUniversidade Estadual Paulista, Hospital of the São PauloAssociação Paulista de Medicina - APMUniversidade Estadual Paulista (Unesp)Matsuoka, Oscar Tadashi [UNESP]Shibao, Simone [UNESP]Leone, Cléa Rodrigues [UNESP]2021-07-14T10:28:24Z2021-07-14T10:28:24Z2007-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article85-90application/pdfhttp://dx.doi.org/10.1590/S1516-31802007000200004Sao Paulo Medical Journal. São Paulo, SP, Brazil: Associação Paulista de Medicina - APM, v. 125, n. 2, p. 85-90, 2007.1516-31801806-9460http://hdl.handle.net/11449/21170410.1590/S1516-31802007000200004S1516-31802007000200004S1516-31802007000200004.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSao Paulo Medical Journalinfo:eu-repo/semantics/openAccess2023-10-29T06:08:55Zoai:repositorio.unesp.br:11449/211704Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:22:30.504794Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Blood pressure and kidney size in term newborns with intrauterine growth restriction
Pressão arterial e tamanho renal em recém-nascidos no termo com restrição de crescimento intra-uterino
title Blood pressure and kidney size in term newborns with intrauterine growth restriction
spellingShingle Blood pressure and kidney size in term newborns with intrauterine growth restriction
Matsuoka, Oscar Tadashi [UNESP]
Blood pressure
Fetal growth retardation
Newborn infant
Kidney
Renin
Pressão arterial
Retardo do crescimento fetal
Recém-nascido
Rim
Renina
title_short Blood pressure and kidney size in term newborns with intrauterine growth restriction
title_full Blood pressure and kidney size in term newborns with intrauterine growth restriction
title_fullStr Blood pressure and kidney size in term newborns with intrauterine growth restriction
title_full_unstemmed Blood pressure and kidney size in term newborns with intrauterine growth restriction
title_sort Blood pressure and kidney size in term newborns with intrauterine growth restriction
author Matsuoka, Oscar Tadashi [UNESP]
author_facet Matsuoka, Oscar Tadashi [UNESP]
Shibao, Simone [UNESP]
Leone, Cléa Rodrigues [UNESP]
author_role author
author2 Shibao, Simone [UNESP]
Leone, Cléa Rodrigues [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Matsuoka, Oscar Tadashi [UNESP]
Shibao, Simone [UNESP]
Leone, Cléa Rodrigues [UNESP]
dc.subject.por.fl_str_mv Blood pressure
Fetal growth retardation
Newborn infant
Kidney
Renin
Pressão arterial
Retardo do crescimento fetal
Recém-nascido
Rim
Renina
topic Blood pressure
Fetal growth retardation
Newborn infant
Kidney
Renin
Pressão arterial
Retardo do crescimento fetal
Recém-nascido
Rim
Renina
description CONTEXT AND OBJECTIVE: Low birth weight is associated with higher blood pressure in childhood and adulthood. The aim of this study was to investigate the influence of intrauterine growth restriction (IUGR) on newborn systolic blood pressure (SBP). DESIGN AND SETTING: Prospective comparative study at Neonatal and Intensive in Clinical Pediatrics Division, Maternity Hospital in Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo. METHODS: 35 newborns with IUGR and 35 without IUGR were compared. Healthy term newborns without malformations, with Apgar score at fifth minute > 6 were included. Birth weight, kidney weight/birth weight ratio, kidney weight (ultrasound scan), plasma renin activity (PRA) and SBP evolution were analyzed during the first month of life (on 1st, 3rd, 7th and 30th days). RESULTS: SBP evolution, kidney weight/birth weight ratio and PRA did not differ between the two groups. In newborns with IUGR, SBP presented positive correlations with birth weight (r = 0.387 p = 0.026) and BMI (r = 0.412 p = 0.017) on the 7th day of life. Positive correlations with birth weight (r = 0.440 p = 0.01) and birth length (r = 0.386 p = 0.026) were also seen on the 30th day. There was an inverse correlation on the 7th day between SBP and kidney weight/birth weight ratio (r = -0.420 p = 0.014), but this did not persist to the end of the month. CONCLUSIONS: IUGR seems not to have any influence on SBP, PRA or kidney weight among term newborns during their first month of life.
publishDate 2007
dc.date.none.fl_str_mv 2007-03
2021-07-14T10:28:24Z
2021-07-14T10:28:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-31802007000200004
Sao Paulo Medical Journal. São Paulo, SP, Brazil: Associação Paulista de Medicina - APM, v. 125, n. 2, p. 85-90, 2007.
1516-3180
1806-9460
http://hdl.handle.net/11449/211704
10.1590/S1516-31802007000200004
S1516-31802007000200004
S1516-31802007000200004.pdf
url http://dx.doi.org/10.1590/S1516-31802007000200004
http://hdl.handle.net/11449/211704
identifier_str_mv Sao Paulo Medical Journal. São Paulo, SP, Brazil: Associação Paulista de Medicina - APM, v. 125, n. 2, p. 85-90, 2007.
1516-3180
1806-9460
10.1590/S1516-31802007000200004
S1516-31802007000200004
S1516-31802007000200004.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sao Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 85-90
application/pdf
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128639153209344

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