Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://cpro4576.publiccloud.com.br:8080/editora//upload/trabalho/v50/v50n4a1.pdf http://hdl.handle.net/11449/13801 |
Resumo: | The antimicrobial activity, of danofloxacin, a new 4-fluoroquinolone for exclusive use in Veterinary Medicine, was compared in vitro with other seven drugs against 200 strains of Staphylococcus aureus isolated from bovine mastitis. By using the antimicrobial disk diffusion method (Bauer-Kirby), the results showed that the imipenem (100%), trimerhoprim/sulfamethoxazole (98.9%), cefuroxime (97.3%) were the most effective drugs taking into consideration the percentuals of sensitiveness. However, considering the percentuals of the moderately sensitive strains, danofloxacin emerged as the third most active drug. The antimicrobial dilution susceptibility test used to study the minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of danofloxacin, characterized its significative antimicrobial activity by showing a close relationship between both concentrations (MIC90%= 18 mu g/ml - MBC90% = 0.23 mu g/ml), as well as a MIC/MBC ratio of 1:1 and 1:2 for most of tested strains. |
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Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovinaAntimicrobial activity of danofloxacin and seven other drugs against Staphylococcus aureus from bovine mastitisbovineStaphylococcus aureusmastitisdanofloxacinThe antimicrobial activity, of danofloxacin, a new 4-fluoroquinolone for exclusive use in Veterinary Medicine, was compared in vitro with other seven drugs against 200 strains of Staphylococcus aureus isolated from bovine mastitis. By using the antimicrobial disk diffusion method (Bauer-Kirby), the results showed that the imipenem (100%), trimerhoprim/sulfamethoxazole (98.9%), cefuroxime (97.3%) were the most effective drugs taking into consideration the percentuals of sensitiveness. However, considering the percentuals of the moderately sensitive strains, danofloxacin emerged as the third most active drug. The antimicrobial dilution susceptibility test used to study the minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of danofloxacin, characterized its significative antimicrobial activity by showing a close relationship between both concentrations (MIC90%= 18 mu g/ml - MBC90% = 0.23 mu g/ml), as well as a MIC/MBC ratio of 1:1 and 1:2 for most of tested strains.Univ Estadual Paulista, UNESP, Inst Biociencias, BR-18618000 Botucatu, SP, BrazilUNESP, Fac Med Vet & Zootecnia, Dept Higiene Vet & Saúde Publ, BR-18618000 Botucatu, SP, BrazilUniv Estadual Paulista, UNESP, Inst Biociencias, BR-18618000 Botucatu, SP, BrazilUNESP, Fac Med Vet & Zootecnia, Dept Higiene Vet & Saúde Publ, BR-18618000 Botucatu, SP, BrazilArquivo Brasileiro Medicina Veterinaria ZootecniaUniversidade Estadual Paulista (Unesp)Cruz, A. D.Batista, GCMModolo, JRGottschalk, A. F.Lopes, CAM2014-05-20T13:39:46Z2014-05-20T13:39:46Z1998-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article369-373application/pdfhttp://cpro4576.publiccloud.com.br:8080/editora//upload/trabalho/v50/v50n4a1.pdfArquivo Brasileiro de Medicina Veterinaria e Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 50, n. 4, p. 369-373, 1998.0102-0935http://hdl.handle.net/11449/13801WOS:000078326400001WOS000078326400001.pdf6221640440438631Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivo Brasileiro de Medicina Veterinária e Zootecnia0.2860,248info:eu-repo/semantics/openAccess2023-10-21T06:04:55Zoai:repositorio.unesp.br:11449/13801Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:30:25.758891Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina Antimicrobial activity of danofloxacin and seven other drugs against Staphylococcus aureus from bovine mastitis |
title |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
spellingShingle |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina Cruz, A. D. bovine Staphylococcus aureus mastitis danofloxacin |
title_short |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
title_full |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
title_fullStr |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
title_full_unstemmed |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
title_sort |
Atividade in vitro do danofloxacin e de sete drogas antimicrobianas frente a linhagens de Staphylococcus aureus de mastite bovina |
author |
Cruz, A. D. |
author_facet |
Cruz, A. D. Batista, GCM Modolo, JR Gottschalk, A. F. Lopes, CAM |
author_role |
author |
author2 |
Batista, GCM Modolo, JR Gottschalk, A. F. Lopes, CAM |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Cruz, A. D. Batista, GCM Modolo, JR Gottschalk, A. F. Lopes, CAM |
dc.subject.por.fl_str_mv |
bovine Staphylococcus aureus mastitis danofloxacin |
topic |
bovine Staphylococcus aureus mastitis danofloxacin |
description |
The antimicrobial activity, of danofloxacin, a new 4-fluoroquinolone for exclusive use in Veterinary Medicine, was compared in vitro with other seven drugs against 200 strains of Staphylococcus aureus isolated from bovine mastitis. By using the antimicrobial disk diffusion method (Bauer-Kirby), the results showed that the imipenem (100%), trimerhoprim/sulfamethoxazole (98.9%), cefuroxime (97.3%) were the most effective drugs taking into consideration the percentuals of sensitiveness. However, considering the percentuals of the moderately sensitive strains, danofloxacin emerged as the third most active drug. The antimicrobial dilution susceptibility test used to study the minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of danofloxacin, characterized its significative antimicrobial activity by showing a close relationship between both concentrations (MIC90%= 18 mu g/ml - MBC90% = 0.23 mu g/ml), as well as a MIC/MBC ratio of 1:1 and 1:2 for most of tested strains. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-08-01 2014-05-20T13:39:46Z 2014-05-20T13:39:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://cpro4576.publiccloud.com.br:8080/editora//upload/trabalho/v50/v50n4a1.pdf Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 50, n. 4, p. 369-373, 1998. 0102-0935 http://hdl.handle.net/11449/13801 WOS:000078326400001 WOS000078326400001.pdf 6221640440438631 |
url |
http://cpro4576.publiccloud.com.br:8080/editora//upload/trabalho/v50/v50n4a1.pdf http://hdl.handle.net/11449/13801 |
identifier_str_mv |
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 50, n. 4, p. 369-373, 1998. 0102-0935 WOS:000078326400001 WOS000078326400001.pdf 6221640440438631 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia 0.286 0,248 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
369-373 application/pdf |
dc.publisher.none.fl_str_mv |
Arquivo Brasileiro Medicina Veterinaria Zootecnia |
publisher.none.fl_str_mv |
Arquivo Brasileiro Medicina Veterinaria Zootecnia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128523392516096 |