Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1136/vr.142.20.541 http://hdl.handle.net/11449/219217 |
Resumo: | This prospective clinical study compared the physiological effects of two commonly used anaesthetic induction techniques in horses maintained with halothane. One hundred horses admitted for elective surgery were randomly allocated to receive either guaiphenesin (to effect) and thiopentone (5 mg/kg), or detomidine (20 μg/kg) and ketamine (2 mg/kg) for the induction of anaesthesia after acepromazine premedication. Anaesthesia was maintained with halothane in oxygen. There were no significant differences in breed, age, sex, weight, type of surgery and duration of anaesthesia between the groups. Immediately after induction of anaesthesia heart rate was higher after guaiphenesin and thiopentone, and arterial blood pressure was higher after detomidine and ketamine. Thereafter hypotension, often necessitating an infusion of dobutamine, developed in both groups. Arterial blood gases and respiratory rates were similar in the two groups. There were no significant differences between the groups in the subjectively scored quality of induction and recovery, or in recovery time. |
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Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothaneThis prospective clinical study compared the physiological effects of two commonly used anaesthetic induction techniques in horses maintained with halothane. One hundred horses admitted for elective surgery were randomly allocated to receive either guaiphenesin (to effect) and thiopentone (5 mg/kg), or detomidine (20 μg/kg) and ketamine (2 mg/kg) for the induction of anaesthesia after acepromazine premedication. Anaesthesia was maintained with halothane in oxygen. There were no significant differences in breed, age, sex, weight, type of surgery and duration of anaesthesia between the groups. Immediately after induction of anaesthesia heart rate was higher after guaiphenesin and thiopentone, and arterial blood pressure was higher after detomidine and ketamine. Thereafter hypotension, often necessitating an infusion of dobutamine, developed in both groups. Arterial blood gases and respiratory rates were similar in the two groups. There were no significant differences between the groups in the subjectively scored quality of induction and recovery, or in recovery time.Animal Health Trust, PO Box 5, Newmarket, Suffolk CB8 7DWDepartment of Surgical Science School of Veterinary Medicine University of California, Davis, CA 95616-8745Dept. of Clin. Veterinary Medicine, Madingley Road, Cambridge CB3 0ESSchool of Veterinary Science University of Bristol, Langford, Bristol BS18 7DUUniversity of S. Paulo, 18618-000, Botucatu, SPAnimal Health TrustUniversity of CaliforniaDept. of Clin. Veterinary MedicineUniversity of BristolUniversity of S. PauloBennett, R. C.Taylor, P. M.Brearley, J. C.Johnson, C. B.Luna, S. P.L.2022-04-28T18:54:26Z2022-04-28T18:54:26Z1998-05-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article541-545http://dx.doi.org/10.1136/vr.142.20.541Veterinary Record, v. 142, n. 20, p. 541-545, 1998.0042-4900http://hdl.handle.net/11449/21921710.1136/vr.142.20.5412-s2.0-0032537312Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Recordinfo:eu-repo/semantics/openAccess2022-04-28T18:54:26Zoai:repositorio.unesp.br:11449/219217Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:29:30.660119Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
title |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
spellingShingle |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane Bennett, R. C. |
title_short |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
title_full |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
title_fullStr |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
title_full_unstemmed |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
title_sort |
Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane |
author |
Bennett, R. C. |
author_facet |
Bennett, R. C. Taylor, P. M. Brearley, J. C. Johnson, C. B. Luna, S. P.L. |
author_role |
author |
author2 |
Taylor, P. M. Brearley, J. C. Johnson, C. B. Luna, S. P.L. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Animal Health Trust University of California Dept. of Clin. Veterinary Medicine University of Bristol University of S. Paulo |
dc.contributor.author.fl_str_mv |
Bennett, R. C. Taylor, P. M. Brearley, J. C. Johnson, C. B. Luna, S. P.L. |
description |
This prospective clinical study compared the physiological effects of two commonly used anaesthetic induction techniques in horses maintained with halothane. One hundred horses admitted for elective surgery were randomly allocated to receive either guaiphenesin (to effect) and thiopentone (5 mg/kg), or detomidine (20 μg/kg) and ketamine (2 mg/kg) for the induction of anaesthesia after acepromazine premedication. Anaesthesia was maintained with halothane in oxygen. There were no significant differences in breed, age, sex, weight, type of surgery and duration of anaesthesia between the groups. Immediately after induction of anaesthesia heart rate was higher after guaiphenesin and thiopentone, and arterial blood pressure was higher after detomidine and ketamine. Thereafter hypotension, often necessitating an infusion of dobutamine, developed in both groups. Arterial blood gases and respiratory rates were similar in the two groups. There were no significant differences between the groups in the subjectively scored quality of induction and recovery, or in recovery time. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-05-16 2022-04-28T18:54:26Z 2022-04-28T18:54:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1136/vr.142.20.541 Veterinary Record, v. 142, n. 20, p. 541-545, 1998. 0042-4900 http://hdl.handle.net/11449/219217 10.1136/vr.142.20.541 2-s2.0-0032537312 |
url |
http://dx.doi.org/10.1136/vr.142.20.541 http://hdl.handle.net/11449/219217 |
identifier_str_mv |
Veterinary Record, v. 142, n. 20, p. 541-545, 1998. 0042-4900 10.1136/vr.142.20.541 2-s2.0-0032537312 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Veterinary Record |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
541-545 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128938325573632 |