Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.marpolbul.2020.111329 http://hdl.handle.net/11449/200865 |
Resumo: | Coastal areas with important economic activities have high levels of contamination by metals, pathogenic bacteria, among other contaminants. The emergence of antibiotic-resistant bacteria is a global problem of public health. Carbapenem resistant Enterobacteriaceae (CRE) are a serious threat. The occurrence of carbapenem resistant bacteria was investigated in waters and sediments of a Brazilian coastal area, characterized by high levels of contamination. The samples of water and sediment were collected in two areas of the coast of São Paulo (Brazil). The study involved the characterization of the molecular mechanisms associated with the carbapenem resistance phenotype. No genes were detected for β-lactamases but the absence and/or presence of mutations in outer membrane proteins (OMPs) may justify the detected phenotype. The presented results show the need for further studies that allow a review of the current legislation and the importance of the reevaluation of monitoring policies of these environments. |
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Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterizationBacterial resistanceCo-selectionCoastal contaminationPort contaminationCoastal areas with important economic activities have high levels of contamination by metals, pathogenic bacteria, among other contaminants. The emergence of antibiotic-resistant bacteria is a global problem of public health. Carbapenem resistant Enterobacteriaceae (CRE) are a serious threat. The occurrence of carbapenem resistant bacteria was investigated in waters and sediments of a Brazilian coastal area, characterized by high levels of contamination. The samples of water and sediment were collected in two areas of the coast of São Paulo (Brazil). The study involved the characterization of the molecular mechanisms associated with the carbapenem resistance phenotype. No genes were detected for β-lactamases but the absence and/or presence of mutations in outer membrane proteins (OMPs) may justify the detected phenotype. The presented results show the need for further studies that allow a review of the current legislation and the importance of the reevaluation of monitoring policies of these environments.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Office of Electricity Delivery and Energy ReliabilityCentro de Estudos Ambientais e Marinhos, Universidade de AveiroDepartament of Biochemistry and Microbiology São Paulo State University (UNESP)Marine and Environmental Microbiology Laboratory São Paulo State University (UNESP) Biosciences InstituteCESAM & Department of Biology University of AveiroDepartament of Biochemistry and Microbiology São Paulo State University (UNESP)Marine and Environmental Microbiology Laboratory São Paulo State University (UNESP) Biosciences InstituteCAPES: 001CAPES: 88881.190285/2018-01Office of Electricity Delivery and Energy Reliability: CEECIND/01463/2017Centro de Estudos Ambientais e Marinhos, Universidade de Aveiro: UIDP/50017/2020+UIDB/50017/2020Universidade Estadual Paulista (Unesp)University of AveiroAndrade, Vanessa Costa [UNESP]Caetano, TâniaMendo, SóniaOliveira, Ana Júlia Fernandes Cardoso de [UNESP]2020-12-12T02:18:09Z2020-12-12T02:18:09Z2020-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.marpolbul.2020.111329Marine Pollution Bulletin, v. 159.1879-33630025-326Xhttp://hdl.handle.net/11449/20086510.1016/j.marpolbul.2020.1113292-s2.0-85089107686Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMarine Pollution Bulletininfo:eu-repo/semantics/openAccess2021-10-23T15:25:37Zoai:repositorio.unesp.br:11449/200865Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:04:41.043178Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
title |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
spellingShingle |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization Andrade, Vanessa Costa [UNESP] Bacterial resistance Co-selection Coastal contamination Port contamination |
title_short |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
title_full |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
title_fullStr |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
title_full_unstemmed |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
title_sort |
Carbapenem resistant Enterobacteriaceae from port areas in São Paulo State (Brazil): Isolation and molecular characterization |
author |
Andrade, Vanessa Costa [UNESP] |
author_facet |
Andrade, Vanessa Costa [UNESP] Caetano, Tânia Mendo, Sónia Oliveira, Ana Júlia Fernandes Cardoso de [UNESP] |
author_role |
author |
author2 |
Caetano, Tânia Mendo, Sónia Oliveira, Ana Júlia Fernandes Cardoso de [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Aveiro |
dc.contributor.author.fl_str_mv |
Andrade, Vanessa Costa [UNESP] Caetano, Tânia Mendo, Sónia Oliveira, Ana Júlia Fernandes Cardoso de [UNESP] |
dc.subject.por.fl_str_mv |
Bacterial resistance Co-selection Coastal contamination Port contamination |
topic |
Bacterial resistance Co-selection Coastal contamination Port contamination |
description |
Coastal areas with important economic activities have high levels of contamination by metals, pathogenic bacteria, among other contaminants. The emergence of antibiotic-resistant bacteria is a global problem of public health. Carbapenem resistant Enterobacteriaceae (CRE) are a serious threat. The occurrence of carbapenem resistant bacteria was investigated in waters and sediments of a Brazilian coastal area, characterized by high levels of contamination. The samples of water and sediment were collected in two areas of the coast of São Paulo (Brazil). The study involved the characterization of the molecular mechanisms associated with the carbapenem resistance phenotype. No genes were detected for β-lactamases but the absence and/or presence of mutations in outer membrane proteins (OMPs) may justify the detected phenotype. The presented results show the need for further studies that allow a review of the current legislation and the importance of the reevaluation of monitoring policies of these environments. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:18:09Z 2020-12-12T02:18:09Z 2020-10-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.marpolbul.2020.111329 Marine Pollution Bulletin, v. 159. 1879-3363 0025-326X http://hdl.handle.net/11449/200865 10.1016/j.marpolbul.2020.111329 2-s2.0-85089107686 |
url |
http://dx.doi.org/10.1016/j.marpolbul.2020.111329 http://hdl.handle.net/11449/200865 |
identifier_str_mv |
Marine Pollution Bulletin, v. 159. 1879-3363 0025-326X 10.1016/j.marpolbul.2020.111329 2-s2.0-85089107686 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Marine Pollution Bulletin |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129015822680064 |