A comparison of immunological, chemical and surgical castration of Nelore bulls
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.theriogenology.2021.03.021 http://hdl.handle.net/11449/207615 |
Resumo: | The objective was to compare effects of immunological, chemical and surgical castrations on testicular characteristics, scrotal surface temperatures, sperm quality, and serum testosterone concentrations in Bos indicus bulls. Eighty Nelore bulls (∼20 mo) were grazed on pasture, fed a supplement and slaughtered at ∼480 kg. Bulls were allocated into four groups (n = 20/group). The control group (CON) was non-castrated and there were three castration methods: immune (IMM - Bopriva®), injected on D-30, D30 and D60; chemical (CHE), an intratesticular injection of 40% CaCl2 + 0.5% dimethylsulfoxide on D0; and surgical (SUR) on D0. The CHE group were surgically castrated on D60, due to testicular swelling and necrosis of scrotal skin. Most scrotal surface temperatures (infrared thermography) were significantly higher on D15 in CHE and SUR compared to CON, due to inflammation. All bulls were subjected to a breeding soundness evaluation on D-7 and slaughtered on D220. Scrotal circumference and testicular volume did not differ among groups (P > 0.05) at D0, but at D15, both end points were highest (P < 0.05) in the CHE group (due to swelling), although both end points were smaller for IMM versus CON (P < 0.05) at D60 and D150. Sperm motility in the IMM group was ∼50 and 10% of that in the CON group on D60 and D150, respectively. For the IMM group, serum testosterone concentrations were similar on D0 and D15 (but ∼50% of CHE or SUR on D0, attributed to the first treatment on D-30), and had decreased ∼70% on D60 and D150, whereas in the CHE and SUR groups, there were ∼80–90% decreases in testosterone after D0. In conclusion, immunological castration was a viable alternative to surgical castration, as it supressed testosterone production and spermatogenesis, with the benefits of being much less invasive, with better animal welfare and less stress. |
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A comparison of immunological, chemical and surgical castration of Nelore bullsImmune castrationInfrared thermographyScrotal surface temperatureSurgeryTestesThe objective was to compare effects of immunological, chemical and surgical castrations on testicular characteristics, scrotal surface temperatures, sperm quality, and serum testosterone concentrations in Bos indicus bulls. Eighty Nelore bulls (∼20 mo) were grazed on pasture, fed a supplement and slaughtered at ∼480 kg. Bulls were allocated into four groups (n = 20/group). The control group (CON) was non-castrated and there were three castration methods: immune (IMM - Bopriva®), injected on D-30, D30 and D60; chemical (CHE), an intratesticular injection of 40% CaCl2 + 0.5% dimethylsulfoxide on D0; and surgical (SUR) on D0. The CHE group were surgically castrated on D60, due to testicular swelling and necrosis of scrotal skin. Most scrotal surface temperatures (infrared thermography) were significantly higher on D15 in CHE and SUR compared to CON, due to inflammation. All bulls were subjected to a breeding soundness evaluation on D-7 and slaughtered on D220. Scrotal circumference and testicular volume did not differ among groups (P > 0.05) at D0, but at D15, both end points were highest (P < 0.05) in the CHE group (due to swelling), although both end points were smaller for IMM versus CON (P < 0.05) at D60 and D150. Sperm motility in the IMM group was ∼50 and 10% of that in the CON group on D60 and D150, respectively. For the IMM group, serum testosterone concentrations were similar on D0 and D15 (but ∼50% of CHE or SUR on D0, attributed to the first treatment on D-30), and had decreased ∼70% on D60 and D150, whereas in the CHE and SUR groups, there were ∼80–90% decreases in testosterone after D0. In conclusion, immunological castration was a viable alternative to surgical castration, as it supressed testosterone production and spermatogenesis, with the benefits of being much less invasive, with better animal welfare and less stress.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)São Paulo State University (UNESP) School of Veterinary Medicine and Animal Science Department of Veterinary Surgery and Animal ReproductionUniversidade do Oeste Paulista Department of Graduate Studies in Animal ScienceFaculty of Veterinary Medicine Department of Production Animal Health University of CalgarySão Paulo State University (UNESP) Faculty of Agricultural and Technological Sciences Department of Animal Science and TechnologySão Paulo State University (UNESP) School of Veterinary Medicine and Animal Science Department of Veterinary Surgery and Animal ReproductionSão Paulo State University (UNESP) Faculty of Agricultural and Technological Sciences Department of Animal Science and TechnologyCAPES: 01Universidade Estadual Paulista (Unesp)Universidade do Oeste PaulistaUniversity of CalgaryYamada, Paulo Henrique [UNESP]Codognoto, Viviane Maria [UNESP]Rydygier de Ruediger, FelipeMayara da Silva, Kelry [UNESP]Aristizábal, Viviana Vallejo [UNESP]Kastelic, John PatrickRizzoto, GuilhermeFerreira de Souza, Fabiana [UNESP]Gomes de Soutello, Ricardo Velludo [UNESP]Mungai Chacur, Marcelo GeorgeOba, Eunice [UNESP]2021-06-25T10:58:06Z2021-06-25T10:58:06Z2021-07-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9-13http://dx.doi.org/10.1016/j.theriogenology.2021.03.021Theriogenology, v. 169, p. 9-13.0093-691Xhttp://hdl.handle.net/11449/20761510.1016/j.theriogenology.2021.03.0212-s2.0-85104366933Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTheriogenologyinfo:eu-repo/semantics/openAccess2024-09-09T14:01:31Zoai:repositorio.unesp.br:11449/207615Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:01:31Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
title |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
spellingShingle |
A comparison of immunological, chemical and surgical castration of Nelore bulls Yamada, Paulo Henrique [UNESP] Immune castration Infrared thermography Scrotal surface temperature Surgery Testes |
title_short |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
title_full |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
title_fullStr |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
title_full_unstemmed |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
title_sort |
A comparison of immunological, chemical and surgical castration of Nelore bulls |
author |
Yamada, Paulo Henrique [UNESP] |
author_facet |
Yamada, Paulo Henrique [UNESP] Codognoto, Viviane Maria [UNESP] Rydygier de Ruediger, Felipe Mayara da Silva, Kelry [UNESP] Aristizábal, Viviana Vallejo [UNESP] Kastelic, John Patrick Rizzoto, Guilherme Ferreira de Souza, Fabiana [UNESP] Gomes de Soutello, Ricardo Velludo [UNESP] Mungai Chacur, Marcelo George Oba, Eunice [UNESP] |
author_role |
author |
author2 |
Codognoto, Viviane Maria [UNESP] Rydygier de Ruediger, Felipe Mayara da Silva, Kelry [UNESP] Aristizábal, Viviana Vallejo [UNESP] Kastelic, John Patrick Rizzoto, Guilherme Ferreira de Souza, Fabiana [UNESP] Gomes de Soutello, Ricardo Velludo [UNESP] Mungai Chacur, Marcelo George Oba, Eunice [UNESP] |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade do Oeste Paulista University of Calgary |
dc.contributor.author.fl_str_mv |
Yamada, Paulo Henrique [UNESP] Codognoto, Viviane Maria [UNESP] Rydygier de Ruediger, Felipe Mayara da Silva, Kelry [UNESP] Aristizábal, Viviana Vallejo [UNESP] Kastelic, John Patrick Rizzoto, Guilherme Ferreira de Souza, Fabiana [UNESP] Gomes de Soutello, Ricardo Velludo [UNESP] Mungai Chacur, Marcelo George Oba, Eunice [UNESP] |
dc.subject.por.fl_str_mv |
Immune castration Infrared thermography Scrotal surface temperature Surgery Testes |
topic |
Immune castration Infrared thermography Scrotal surface temperature Surgery Testes |
description |
The objective was to compare effects of immunological, chemical and surgical castrations on testicular characteristics, scrotal surface temperatures, sperm quality, and serum testosterone concentrations in Bos indicus bulls. Eighty Nelore bulls (∼20 mo) were grazed on pasture, fed a supplement and slaughtered at ∼480 kg. Bulls were allocated into four groups (n = 20/group). The control group (CON) was non-castrated and there were three castration methods: immune (IMM - Bopriva®), injected on D-30, D30 and D60; chemical (CHE), an intratesticular injection of 40% CaCl2 + 0.5% dimethylsulfoxide on D0; and surgical (SUR) on D0. The CHE group were surgically castrated on D60, due to testicular swelling and necrosis of scrotal skin. Most scrotal surface temperatures (infrared thermography) were significantly higher on D15 in CHE and SUR compared to CON, due to inflammation. All bulls were subjected to a breeding soundness evaluation on D-7 and slaughtered on D220. Scrotal circumference and testicular volume did not differ among groups (P > 0.05) at D0, but at D15, both end points were highest (P < 0.05) in the CHE group (due to swelling), although both end points were smaller for IMM versus CON (P < 0.05) at D60 and D150. Sperm motility in the IMM group was ∼50 and 10% of that in the CON group on D60 and D150, respectively. For the IMM group, serum testosterone concentrations were similar on D0 and D15 (but ∼50% of CHE or SUR on D0, attributed to the first treatment on D-30), and had decreased ∼70% on D60 and D150, whereas in the CHE and SUR groups, there were ∼80–90% decreases in testosterone after D0. In conclusion, immunological castration was a viable alternative to surgical castration, as it supressed testosterone production and spermatogenesis, with the benefits of being much less invasive, with better animal welfare and less stress. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T10:58:06Z 2021-06-25T10:58:06Z 2021-07-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.theriogenology.2021.03.021 Theriogenology, v. 169, p. 9-13. 0093-691X http://hdl.handle.net/11449/207615 10.1016/j.theriogenology.2021.03.021 2-s2.0-85104366933 |
url |
http://dx.doi.org/10.1016/j.theriogenology.2021.03.021 http://hdl.handle.net/11449/207615 |
identifier_str_mv |
Theriogenology, v. 169, p. 9-13. 0093-691X 10.1016/j.theriogenology.2021.03.021 2-s2.0-85104366933 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Theriogenology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
9-13 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021330762858496 |