Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4162/nrp.2014.8.5.550 http://hdl.handle.net/11449/117553 |
Resumo: | BACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and the alteration of the antioxidant performance in vivo.SUBJECTS AND MATERIALS: Absorption kinetics of phytochemicals in Angelica keiskei were determined in healthy older adults (>60 y, n = 5) and subjects with metabolic syndrome (n = 5). Subjects consumed 5 g dry Angelica keiskei powder encapsulated in gelatin capsules with a low flavonoid and carotenoid liquid meal. Plasma samples were collected at baseline, 0.5, 1, 2, 3, 4, 5, 6, 7, and 8 h. Samples were analyzed for flavonoids and carotenoids using HPLC systems with electrochemical and UV detection, respectively, and for total antioxidant performance by fluorometry.RESULTS: After ingestion of Angelica keiskei increases in plasma quercetin concentrations were observed at 1-3 and 6-8 hr in the healthy group and at all time points in the metabolic syndrome group compared to baseline (P < 0.05). Plasma lutein concentrations were significantly elevated in both the healthy and metabolic syndrome groups at 8 hr (P < 0.05). Significant increases in total antioxidant performance were also observed in both the healthy and the metabolic syndrome groups compared to baseline (P < 0.05).CONCLUSIONS: Findings of this study clearly demonstrate the bioavailability of phytonutrients of Angelica keiskei and their ability to increase antioxidant status in humans. |
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Repositório Institucional da UNESP |
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Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic studyAngelica keiskeiquercetinluteinabsorption kinetictotal antioxidant performanceBACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and the alteration of the antioxidant performance in vivo.SUBJECTS AND MATERIALS: Absorption kinetics of phytochemicals in Angelica keiskei were determined in healthy older adults (>60 y, n = 5) and subjects with metabolic syndrome (n = 5). Subjects consumed 5 g dry Angelica keiskei powder encapsulated in gelatin capsules with a low flavonoid and carotenoid liquid meal. Plasma samples were collected at baseline, 0.5, 1, 2, 3, 4, 5, 6, 7, and 8 h. Samples were analyzed for flavonoids and carotenoids using HPLC systems with electrochemical and UV detection, respectively, and for total antioxidant performance by fluorometry.RESULTS: After ingestion of Angelica keiskei increases in plasma quercetin concentrations were observed at 1-3 and 6-8 hr in the healthy group and at all time points in the metabolic syndrome group compared to baseline (P < 0.05). Plasma lutein concentrations were significantly elevated in both the healthy and metabolic syndrome groups at 8 hr (P < 0.05). Significant increases in total antioxidant performance were also observed in both the healthy and the metabolic syndrome groups compared to baseline (P < 0.05).CONCLUSIONS: Findings of this study clearly demonstrate the bioavailability of phytonutrients of Angelica keiskei and their ability to increase antioxidant status in humans.BioGreen 21 Program, Rural Development Administration, KoreaU.S. Department of AgricultureTufts Univ, Jean Mayer USDA, Human Nutr Res Ctr Aging, Boston, MA 02111 USASao Paulo State Univ UNESP, Botucatu Med Sch, Dept Internal Med, BR-18618970 Botucatu, SP, BrazilUniv Milan, Dept Pharmaceut Sci, I-20133 Milan, ItalyNatl Acad Agr Sci, Rural Dev Adm, Suwon 441853, South KoreaKonkuk Univ, Coll Biomed & Hlth Sci, Chungju Si 380701, South KoreaSao Paulo State Univ UNESP, Botucatu Med Sch, Dept Internal Med, BR-18618970 Botucatu, SP, BrazilBioGreen 21 Program, Rural Development Administration, Korea20070301034009U.S. Department of Agriculture1950-51000-065-08SKorean Nutrition SocTufts UnivUniversidade Estadual Paulista (Unesp)Univ MilanNatl Acad Agr SciKonkuk UnivCorrêa, Camila Renata [UNESP]Chen, C-Y. OliverAldini, GiancarloRasmussen, HelenRonchi, Carlos F. [UNESP]Berchieri-Ronchi, Carolina [UNESP]Cho, Soo-MukBlumberg, Jeffrey B.Yeum, Kyung-Jin2015-03-18T15:56:25Z2015-03-18T15:56:25Z2014-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article550-557application/pdfhttp://dx.doi.org/10.4162/nrp.2014.8.5.550Nutrition Research And Practice. Seoul: Korean Nutrition Soc, v. 8, n. 5, p. 550-557, 2014.1976-1457http://hdl.handle.net/11449/11755310.4162/nrp.2014.8.5.550WOS:000342526700011WOS000342526700011.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNutrition Research And Practice1.6350,620info:eu-repo/semantics/openAccess2024-08-14T17:36:10Zoai:repositorio.unesp.br:11449/117553Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:36:10Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
title |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
spellingShingle |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study Corrêa, Camila Renata [UNESP] Angelica keiskei quercetin lutein absorption kinetic total antioxidant performance |
title_short |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
title_full |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
title_fullStr |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
title_full_unstemmed |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
title_sort |
Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study |
author |
Corrêa, Camila Renata [UNESP] |
author_facet |
Corrêa, Camila Renata [UNESP] Chen, C-Y. Oliver Aldini, Giancarlo Rasmussen, Helen Ronchi, Carlos F. [UNESP] Berchieri-Ronchi, Carolina [UNESP] Cho, Soo-Muk Blumberg, Jeffrey B. Yeum, Kyung-Jin |
author_role |
author |
author2 |
Chen, C-Y. Oliver Aldini, Giancarlo Rasmussen, Helen Ronchi, Carlos F. [UNESP] Berchieri-Ronchi, Carolina [UNESP] Cho, Soo-Muk Blumberg, Jeffrey B. Yeum, Kyung-Jin |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Tufts Univ Universidade Estadual Paulista (Unesp) Univ Milan Natl Acad Agr Sci Konkuk Univ |
dc.contributor.author.fl_str_mv |
Corrêa, Camila Renata [UNESP] Chen, C-Y. Oliver Aldini, Giancarlo Rasmussen, Helen Ronchi, Carlos F. [UNESP] Berchieri-Ronchi, Carolina [UNESP] Cho, Soo-Muk Blumberg, Jeffrey B. Yeum, Kyung-Jin |
dc.subject.por.fl_str_mv |
Angelica keiskei quercetin lutein absorption kinetic total antioxidant performance |
topic |
Angelica keiskei quercetin lutein absorption kinetic total antioxidant performance |
description |
BACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and the alteration of the antioxidant performance in vivo.SUBJECTS AND MATERIALS: Absorption kinetics of phytochemicals in Angelica keiskei were determined in healthy older adults (>60 y, n = 5) and subjects with metabolic syndrome (n = 5). Subjects consumed 5 g dry Angelica keiskei powder encapsulated in gelatin capsules with a low flavonoid and carotenoid liquid meal. Plasma samples were collected at baseline, 0.5, 1, 2, 3, 4, 5, 6, 7, and 8 h. Samples were analyzed for flavonoids and carotenoids using HPLC systems with electrochemical and UV detection, respectively, and for total antioxidant performance by fluorometry.RESULTS: After ingestion of Angelica keiskei increases in plasma quercetin concentrations were observed at 1-3 and 6-8 hr in the healthy group and at all time points in the metabolic syndrome group compared to baseline (P < 0.05). Plasma lutein concentrations were significantly elevated in both the healthy and metabolic syndrome groups at 8 hr (P < 0.05). Significant increases in total antioxidant performance were also observed in both the healthy and the metabolic syndrome groups compared to baseline (P < 0.05).CONCLUSIONS: Findings of this study clearly demonstrate the bioavailability of phytonutrients of Angelica keiskei and their ability to increase antioxidant status in humans. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-10-01 2015-03-18T15:56:25Z 2015-03-18T15:56:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4162/nrp.2014.8.5.550 Nutrition Research And Practice. Seoul: Korean Nutrition Soc, v. 8, n. 5, p. 550-557, 2014. 1976-1457 http://hdl.handle.net/11449/117553 10.4162/nrp.2014.8.5.550 WOS:000342526700011 WOS000342526700011.pdf |
url |
http://dx.doi.org/10.4162/nrp.2014.8.5.550 http://hdl.handle.net/11449/117553 |
identifier_str_mv |
Nutrition Research And Practice. Seoul: Korean Nutrition Soc, v. 8, n. 5, p. 550-557, 2014. 1976-1457 10.4162/nrp.2014.8.5.550 WOS:000342526700011 WOS000342526700011.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Nutrition Research And Practice 1.635 0,620 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
550-557 application/pdf |
dc.publisher.none.fl_str_mv |
Korean Nutrition Soc |
publisher.none.fl_str_mv |
Korean Nutrition Soc |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128182858022912 |