Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats

Detalhes bibliográficos
Autor(a) principal: Dela Cruz, Cynthia
Data de Publicação: 2012
Outros Autores: Agati, Leandro B. [UNESP], Pereira, Oduvaldo C. M. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4067/S0717-95022012000200042
http://hdl.handle.net/11449/39818
Resumo: The aim of this study was to compare the effects of resistance exercise associated or not with nandrolone decanoate (ND) on skeletal muscles and body mass of adult male rats. Training protocol consisted of 15 jump sessions, for 6 weeks. ND (5mg/kg) was administered twice a week. The exercise was effective in inducing respective enlargements in fiber areas of extensor digitorum longus and soleus muscles. ND associate with exercise was also able to induce increases in fiber areas these muscles. In untrained group that received nandrolone decanoate an improved in muscular parameters could be observed. In conclusion, the resistance exercise was able to promote an enlargement in fiber areas of both muscles studied without ND treatment, indicating that after a period of time of adaptation to exercise, the muscular effects caused by ND could be achieved in the same way by exercise, without ND and without risks for health.
id UNSP_fb903081b529b224ebc90f6c66db48ed
oai_identifier_str oai:repositorio.unesp.br:11449/39818
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male ratsEfectos del decanoato de nandrolona y el ejercicio de resistencia en el músculo esquelético de ratas machos adultosAnabolic Androgenic SteroidsExtensor Digitorum LongusNandrolone DecanoateResistance TrainingSkeletal MusclesSoleusThe aim of this study was to compare the effects of resistance exercise associated or not with nandrolone decanoate (ND) on skeletal muscles and body mass of adult male rats. Training protocol consisted of 15 jump sessions, for 6 weeks. ND (5mg/kg) was administered twice a week. The exercise was effective in inducing respective enlargements in fiber areas of extensor digitorum longus and soleus muscles. ND associate with exercise was also able to induce increases in fiber areas these muscles. In untrained group that received nandrolone decanoate an improved in muscular parameters could be observed. In conclusion, the resistance exercise was able to promote an enlargement in fiber areas of both muscles studied without ND treatment, indicating that after a period of time of adaptation to exercise, the muscular effects caused by ND could be achieved in the same way by exercise, without ND and without risks for health.El objetivo de este estudio fue comparar los efectos del ejercicio de resistencia con o sin decanoato de nandrolona (DN) en el músculo esquelético y la masa corporal de ratas macho adultas. El protocolo de entrenamiento consistió en 15 sesiones durante 6 semanas de saltos. DN 5mg/kg se administró dos veces durante la semana. El ejercicio fue efectivo para inducir un aumento en el área de las fibras de los músculos extensor largo de los dedos y sóleo. El DN asociado con el ejercicio fue capaz de inducir un aumento en el área de las fibras de los músculos. En el grupo de DN sin entrenamiento, se observó un aumento en los parámetros musculares evaluados. El ejercicio de resistencia sin DN fue capaz de promover un aumento en el área de las fibras de los músculos, lo que indica que después de un período de adaptación al ejercicio, el efecto en los músculos causada por la DN se logró por el ejercicio, sin una gestión DN y los consiguientes peligros para la salud.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de Minas Gerais (UFMG), Inst Biol Sci, Dept Physiol & Biophys, Belo Horizonte, MG, BrazilSão Paulo State Univ UNESP, Inst Biosci, Dept Pharmacol, São Paulo, BrazilSão Paulo State Univ UNESP, Inst Biosci, Dept Pharmacol, São Paulo, BrazilSoc Chilena AnatomiaUniversidade Federal de Minas Gerais (UFMG)Universidade Estadual Paulista (Unesp)Dela Cruz, CynthiaAgati, Leandro B. [UNESP]Pereira, Oduvaldo C. M. [UNESP]2014-05-20T15:30:26Z2014-05-20T15:30:26Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article613-620application/pdfhttp://dx.doi.org/10.4067/S0717-95022012000200042International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 30, n. 2, p. 613-620, 2012.0717-9502http://hdl.handle.net/11449/39818S0717-95022012000200042WOS:000308261900042S0717-95022012000200042.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Morphology0.3360,207info:eu-repo/semantics/openAccess2024-01-21T06:25:33Zoai:repositorio.unesp.br:11449/39818Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:36:31.702156Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
Efectos del decanoato de nandrolona y el ejercicio de resistencia en el músculo esquelético de ratas machos adultos
title Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
spellingShingle Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
Dela Cruz, Cynthia
Anabolic Androgenic Steroids
Extensor Digitorum Longus
Nandrolone Decanoate
Resistance Training
Skeletal Muscles
Soleus
title_short Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
title_full Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
title_fullStr Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
title_full_unstemmed Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
title_sort Effects of nandrolone decanoate and resistance exercise on skeletal muscle in adult male rats
author Dela Cruz, Cynthia
author_facet Dela Cruz, Cynthia
Agati, Leandro B. [UNESP]
Pereira, Oduvaldo C. M. [UNESP]
author_role author
author2 Agati, Leandro B. [UNESP]
Pereira, Oduvaldo C. M. [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de Minas Gerais (UFMG)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Dela Cruz, Cynthia
Agati, Leandro B. [UNESP]
Pereira, Oduvaldo C. M. [UNESP]
dc.subject.por.fl_str_mv Anabolic Androgenic Steroids
Extensor Digitorum Longus
Nandrolone Decanoate
Resistance Training
Skeletal Muscles
Soleus
topic Anabolic Androgenic Steroids
Extensor Digitorum Longus
Nandrolone Decanoate
Resistance Training
Skeletal Muscles
Soleus
description The aim of this study was to compare the effects of resistance exercise associated or not with nandrolone decanoate (ND) on skeletal muscles and body mass of adult male rats. Training protocol consisted of 15 jump sessions, for 6 weeks. ND (5mg/kg) was administered twice a week. The exercise was effective in inducing respective enlargements in fiber areas of extensor digitorum longus and soleus muscles. ND associate with exercise was also able to induce increases in fiber areas these muscles. In untrained group that received nandrolone decanoate an improved in muscular parameters could be observed. In conclusion, the resistance exercise was able to promote an enlargement in fiber areas of both muscles studied without ND treatment, indicating that after a period of time of adaptation to exercise, the muscular effects caused by ND could be achieved in the same way by exercise, without ND and without risks for health.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
2014-05-20T15:30:26Z
2014-05-20T15:30:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4067/S0717-95022012000200042
International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 30, n. 2, p. 613-620, 2012.
0717-9502
http://hdl.handle.net/11449/39818
S0717-95022012000200042
WOS:000308261900042
S0717-95022012000200042.pdf
url http://dx.doi.org/10.4067/S0717-95022012000200042
http://hdl.handle.net/11449/39818
identifier_str_mv International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 30, n. 2, p. 613-620, 2012.
0717-9502
S0717-95022012000200042
WOS:000308261900042
S0717-95022012000200042.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal of Morphology
0.336
0,207
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 613-620
application/pdf
dc.publisher.none.fl_str_mv Soc Chilena Anatomia
publisher.none.fl_str_mv Soc Chilena Anatomia
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129536004456448

Registros relacionados