Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da USC |
Texto Completo: | https://tede2.usc.br:8443/handle/tede/443 |
Resumo: | The survival rate of dental implants, installed in cancer patients, may be influenced by the immediate and late effects of radiotherapy. Hyperbaric Oxygen Therapy (OHB) is considered an adjunct to the installation of implants, since it provides beneficial effects on wound healing through angiogenesis, due to the increase in oxygen tension. However, it is still controversial to prove its efficacy in irradiated patients. Therefore, the objective of this study was to perform a systematic review with meta-analysis, in order to reveal if hyperbaric oxygen therapy influences the survival of dental implants installed in irradiated patients and, consequently, advise the surgeon on the use of OHB as an adjuvant in surgery of implants. A search was made for relevant studies published in the English language using the following databases: PubMed / Medline, Science Direct, Embase and Cochrane Library, between January 1985 and July 2018. The research followed the standards and the PRISMA statement and the systematic review was duly recorded in the PROSPERO database. The inclusion and exclusion criteria were applied and all articles were selected considering the PICO questions. The research in the database resulted in 72 studies, 9 of which were selected using the eligibility criteria, and based on the abstracts. Finally, the eligibility and quality assessment process resulted in 3 studies for statistical analysis. The quality of each included study was assessed using the National Council of Health and Medical Research of Australia (NHMRC). An analysis was performed to determine if OHB decreases the risk of failure of the dental implant. According to the survival rate, there was no evidence that the risk of one implant failing is different between the group case and controle. Considering the number of implant failures, there was no evidence that the risk of implant failure is different between patients who were and were not submitted to OHB. In addition, the risk of an implant failure did not depend on the anatomical site. From this study, it can be affirmed that there are few scientific papers that answer the questioning of this study, so more detailed clinical studies are necessary to be able to conclude about this. |
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Cardoso, Camila Lopes34.975.667.3http://lattes.cnpq.br/240954737595839670399774432http://lattes.cnpq.br/9579539863585945Condezo, Anthony Froy Benites2019-02-08T17:23:32Z2018-11-28Condezo, Anthony Froy Benites. Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise. 2018. 60 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2018.https://tede2.usc.br:8443/handle/tede/443The survival rate of dental implants, installed in cancer patients, may be influenced by the immediate and late effects of radiotherapy. Hyperbaric Oxygen Therapy (OHB) is considered an adjunct to the installation of implants, since it provides beneficial effects on wound healing through angiogenesis, due to the increase in oxygen tension. However, it is still controversial to prove its efficacy in irradiated patients. Therefore, the objective of this study was to perform a systematic review with meta-analysis, in order to reveal if hyperbaric oxygen therapy influences the survival of dental implants installed in irradiated patients and, consequently, advise the surgeon on the use of OHB as an adjuvant in surgery of implants. A search was made for relevant studies published in the English language using the following databases: PubMed / Medline, Science Direct, Embase and Cochrane Library, between January 1985 and July 2018. The research followed the standards and the PRISMA statement and the systematic review was duly recorded in the PROSPERO database. The inclusion and exclusion criteria were applied and all articles were selected considering the PICO questions. The research in the database resulted in 72 studies, 9 of which were selected using the eligibility criteria, and based on the abstracts. Finally, the eligibility and quality assessment process resulted in 3 studies for statistical analysis. The quality of each included study was assessed using the National Council of Health and Medical Research of Australia (NHMRC). An analysis was performed to determine if OHB decreases the risk of failure of the dental implant. According to the survival rate, there was no evidence that the risk of one implant failing is different between the group case and controle. Considering the number of implant failures, there was no evidence that the risk of implant failure is different between patients who were and were not submitted to OHB. In addition, the risk of an implant failure did not depend on the anatomical site. From this study, it can be affirmed that there are few scientific papers that answer the questioning of this study, so more detailed clinical studies are necessary to be able to conclude about this.A taxa de sobrevivência de implantes dentários, instalados em pacientes oncológicos, pode ser influenciada pelos efeitos imediatos e tardios da radioterapia. A Oxigenoterapia Hiperbárica (OHB) é considerada um recurso adjuvante à instalação de implantes, pois proporciona efeitos benéficos na cicatrização das feridas, por meio da angiogênese decorrente do aumento da tensão de oxigênio. Entretanto, ainda é controversa a comprovação de sua eficácia em pacientes irradiados. Diante disso, o objetivo deste trabalho foi realizar uma revisão sistemática com meta-análise, no intuito de revelar se a oxigenoterapia hiperbárica influencia na sobrevivência dos implantes dentários instalados em pacientes irradiados e, consequentemente, orientar o cirurgião sobre o uso da OHB como recurso adjuvante em cirurgia de implantes. Foi realizada uma busca por estudos relevantes publicados em língua inglesa, utilizando os seguintes bancos de dados: PubMed/Medline, Science Direct, Embase e Cochrane Library, entre janeiro de 1985 e julho de 2018. A pesquisa seguiu as normas e a declaração PRISMA e a revisão sistemática foi devidamente registrada no banco de dados PROSPERO. Os critérios de inclusão e exclusão foram aplicados e todos os artigos foram selecionados considerando as questões PICO. A pesquisa na base de dados resultou em 72 estudos, sendo 9 estudos selecionados aplicando os critérios de elegibilidade, e com base nos resumos. Finalmente, o processo de elegibilidade e avaliação de qualidade resultou em 3 estudos para análise estatística. A qualidade de cada estudo incluído foi avaliada utilizando o Conselho Nacional de Saúde e Pesquisa Médica da Austrália (NHMRC). Foi realizada uma análise para saber se a OHB diminui o risco de falha do implante dentário. Segundo a taxa de sobrevivência, não houve evidências de que o risco de um implante falhar seja diferente entre o grupo caso e controle. Considerando o número de falhas dos implantes, não houveram evidências de que o risco de falha seja diferente entre pacientes que foram ou não submetidos à OHB. Além disso, o risco de um implante falhar não dependeu do sítio anatômico. Pode-se afirmar que existem poucos trabalhos científicos que respondam ao questionamento deste estudo, portanto mais estudos clínicos detalhados são necessários para que se possa concluir a respeito.Submitted by Lidyane Lima (lidyane.lima@usc.br) on 2019-02-08T17:23:32Z No. of bitstreams: 1 Oxigenoterapia hiperbarica para instalacao de implantes dentarios em pacientes irradiados - revisao sistematica e metanalise (226642) .pdf: 5061870 bytes, checksum: f8e40cb5cb847b794bb68a0e6db44273 (MD5)Made available in DSpace on 2019-02-08T17:23:32Z (GMT). No. of bitstreams: 1 Oxigenoterapia hiperbarica para instalacao de implantes dentarios em pacientes irradiados - revisao sistematica e metanalise (226642) .pdf: 5061870 bytes, checksum: f8e40cb5cb847b794bb68a0e6db44273 (MD5) Previous issue date: 2018-11-28application/pdfporUniversidade do Sagrado CoraçãoBiologia OralUSCBrasilCiências da Saúde e BiológicasImplantes DentáriosIrradiaçãoRevisão SistemáticaOxigenação HiperbáricaDental ImplantsIrradiationSystematic ReviewHyperbaric OxygenCIENCIAS DA SAUDE::ODONTOLOGIAOxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanáliseHyperbaric oxygen therapy for the installation of dental implants in irradiated patients: systematic review and meta-analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis8043334104093724546600600600-753428887677182963-2070498469879244349info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da USCinstname:Universidade do Sagrado Coração (USC)instacron:USCORIGINALOxigenoterapia hiperbarica para instalacao de implantes dentarios em pacientes irradiados - revisao sistematica e metanalise (226642) .pdfOxigenoterapia hiperbarica para instalacao de implantes dentarios em pacientes irradiados - revisao sistematica e metanalise (226642) .pdfapplication/pdf5061870http://localhost:8080/tede/bitstream/tede/443/2/Oxigenoterapia+hiperbarica+para+instalacao+de+implantes+dentarios+em+pacientes+irradiados+-+revisao+sistematica+e+metanalise+%28226642%29+.pdff8e40cb5cb847b794bb68a0e6db44273MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/443/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/4432019-02-08 15:23:32.699oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttps://tede2.usc.br:8443/http://tede2.usc.br:8080/oai/requestbiblicorjesu@unisagrado.edu.br||normalizacao@usc.bropendoar:2019-02-08T17:23:32Biblioteca Digital de Teses e Dissertações da USC - Universidade do Sagrado Coração (USC)false |
dc.title.eng.fl_str_mv |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
dc.title.alternative.eng.fl_str_mv |
Hyperbaric oxygen therapy for the installation of dental implants in irradiated patients: systematic review and meta-analysis |
title |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
spellingShingle |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise Condezo, Anthony Froy Benites Implantes Dentários Irradiação Revisão Sistemática Oxigenação Hiperbárica Dental Implants Irradiation Systematic Review Hyperbaric Oxygen CIENCIAS DA SAUDE::ODONTOLOGIA |
title_short |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
title_full |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
title_fullStr |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
title_full_unstemmed |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
title_sort |
Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise |
author |
Condezo, Anthony Froy Benites |
author_facet |
Condezo, Anthony Froy Benites |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Cardoso, Camila Lopes |
dc.contributor.advisor1ID.fl_str_mv |
34.975.667.3 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/2409547375958396 |
dc.contributor.authorID.fl_str_mv |
70399774432 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/9579539863585945 |
dc.contributor.author.fl_str_mv |
Condezo, Anthony Froy Benites |
contributor_str_mv |
Cardoso, Camila Lopes |
dc.subject.por.fl_str_mv |
Implantes Dentários Irradiação Revisão Sistemática Oxigenação Hiperbárica |
topic |
Implantes Dentários Irradiação Revisão Sistemática Oxigenação Hiperbárica Dental Implants Irradiation Systematic Review Hyperbaric Oxygen CIENCIAS DA SAUDE::ODONTOLOGIA |
dc.subject.eng.fl_str_mv |
Dental Implants Irradiation Systematic Review Hyperbaric Oxygen |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::ODONTOLOGIA |
description |
The survival rate of dental implants, installed in cancer patients, may be influenced by the immediate and late effects of radiotherapy. Hyperbaric Oxygen Therapy (OHB) is considered an adjunct to the installation of implants, since it provides beneficial effects on wound healing through angiogenesis, due to the increase in oxygen tension. However, it is still controversial to prove its efficacy in irradiated patients. Therefore, the objective of this study was to perform a systematic review with meta-analysis, in order to reveal if hyperbaric oxygen therapy influences the survival of dental implants installed in irradiated patients and, consequently, advise the surgeon on the use of OHB as an adjuvant in surgery of implants. A search was made for relevant studies published in the English language using the following databases: PubMed / Medline, Science Direct, Embase and Cochrane Library, between January 1985 and July 2018. The research followed the standards and the PRISMA statement and the systematic review was duly recorded in the PROSPERO database. The inclusion and exclusion criteria were applied and all articles were selected considering the PICO questions. The research in the database resulted in 72 studies, 9 of which were selected using the eligibility criteria, and based on the abstracts. Finally, the eligibility and quality assessment process resulted in 3 studies for statistical analysis. The quality of each included study was assessed using the National Council of Health and Medical Research of Australia (NHMRC). An analysis was performed to determine if OHB decreases the risk of failure of the dental implant. According to the survival rate, there was no evidence that the risk of one implant failing is different between the group case and controle. Considering the number of implant failures, there was no evidence that the risk of implant failure is different between patients who were and were not submitted to OHB. In addition, the risk of an implant failure did not depend on the anatomical site. From this study, it can be affirmed that there are few scientific papers that answer the questioning of this study, so more detailed clinical studies are necessary to be able to conclude about this. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-11-28 |
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2019-02-08T17:23:32Z |
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Condezo, Anthony Froy Benites. Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise. 2018. 60 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2018. |
dc.identifier.uri.fl_str_mv |
https://tede2.usc.br:8443/handle/tede/443 |
identifier_str_mv |
Condezo, Anthony Froy Benites. Oxigenoterapia hiperbárica para instalação de implantes dentários em pacientes irradiados: revisão sistemática e metanálise. 2018. 60 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2018. |
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