Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/19369 |
Resumo: | OBJECTIVE: This study compares the efficacies of vitamin E and selenium, both individually and in combination, for the prevention of postoperative intra-abdominal adhesions in rats. METHODS: Forty-seven female rats were divided into five groups. The sham animals (S group, n = 7) were given only laparotomies and intraperitoneally received 0.9% NaCl (2 ml). In the 40 other rats, abrasions of the left uterine horn were performed, followed by intraperitoneal administration of either 2 ml 0.9% NaCl (C group), 10 mg vitamin E (vitamin E group), 0.2 mg/kg selenium (Se group) or 10 mg vitamin E with 0.2 mg/kg selenium (vitamin E + Se group), with 10 animals in each treatment group. RESULTS: Adhesion formation was significantly reduced in animals in the Se and vitamin E + Se groups (p |
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Clinics |
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Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models Vitamin ESeleniumIntra-abdominal adhesionHistopathologyRat OBJECTIVE: This study compares the efficacies of vitamin E and selenium, both individually and in combination, for the prevention of postoperative intra-abdominal adhesions in rats. METHODS: Forty-seven female rats were divided into five groups. The sham animals (S group, n = 7) were given only laparotomies and intraperitoneally received 0.9% NaCl (2 ml). In the 40 other rats, abrasions of the left uterine horn were performed, followed by intraperitoneal administration of either 2 ml 0.9% NaCl (C group), 10 mg vitamin E (vitamin E group), 0.2 mg/kg selenium (Se group) or 10 mg vitamin E with 0.2 mg/kg selenium (vitamin E + Se group), with 10 animals in each treatment group. RESULTS: Adhesion formation was significantly reduced in animals in the Se and vitamin E + Se groups (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1936910.1590/S1807-59322011000700021Clinics; Vol. 66 No. 7 (2011); 1247-1251 Clinics; v. 66 n. 7 (2011); 1247-1251 Clinics; Vol. 66 Núm. 7 (2011); 1247-1251 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19369/21432Durmus, Ali SaidYildiz, HamitYaman, IhsanSimsek, Halilinfo:eu-repo/semantics/openAccess2012-05-23T16:36:44Zoai:revistas.usp.br:article/19369Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T16:36:44Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
title |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
spellingShingle |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models Durmus, Ali Said Vitamin E Selenium Intra-abdominal adhesion Histopathology Rat |
title_short |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
title_full |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
title_fullStr |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
title_full_unstemmed |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
title_sort |
Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models |
author |
Durmus, Ali Said |
author_facet |
Durmus, Ali Said Yildiz, Hamit Yaman, Ihsan Simsek, Halil |
author_role |
author |
author2 |
Yildiz, Hamit Yaman, Ihsan Simsek, Halil |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Durmus, Ali Said Yildiz, Hamit Yaman, Ihsan Simsek, Halil |
dc.subject.por.fl_str_mv |
Vitamin E Selenium Intra-abdominal adhesion Histopathology Rat |
topic |
Vitamin E Selenium Intra-abdominal adhesion Histopathology Rat |
description |
OBJECTIVE: This study compares the efficacies of vitamin E and selenium, both individually and in combination, for the prevention of postoperative intra-abdominal adhesions in rats. METHODS: Forty-seven female rats were divided into five groups. The sham animals (S group, n = 7) were given only laparotomies and intraperitoneally received 0.9% NaCl (2 ml). In the 40 other rats, abrasions of the left uterine horn were performed, followed by intraperitoneal administration of either 2 ml 0.9% NaCl (C group), 10 mg vitamin E (vitamin E group), 0.2 mg/kg selenium (Se group) or 10 mg vitamin E with 0.2 mg/kg selenium (vitamin E + Se group), with 10 animals in each treatment group. RESULTS: Adhesion formation was significantly reduced in animals in the Se and vitamin E + Se groups (p |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19369 10.1590/S1807-59322011000700021 |
url |
https://www.revistas.usp.br/clinics/article/view/19369 |
identifier_str_mv |
10.1590/S1807-59322011000700021 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19369/21432 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 66 No. 7 (2011); 1247-1251 Clinics; v. 66 n. 7 (2011); 1247-1251 Clinics; Vol. 66 Núm. 7 (2011); 1247-1251 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222756848009216 |