Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/18411 |
Resumo: | The inflammatory bowel diseases, consisting of Crohn's disease, ulcerative colitis and indeterminate colitis, are distinguished by idiopathic and chronic inflammation of the digestive tract. The distinction between inflammatory bowel diseases and functional bowel disorders, such as irritable bowel syndrome, can be complex because they often present with similar symptoms. Rapid and inexpensive noninvasive tests that are sensitive, specific and simple are needed to prevent patient discomfort, delay in diagnosis, and unnecessary costs. None of the current commercially available serological biomarker tests can be used as a stand-alone diagnostic in clinics. Instead, these are used as an adjunct to endoscopy in diagnosis and prognosis of the disease.Along these lines,, fecal lactoferrin and calprotectin tests seem to be one step further from other tests with larger number of studies, higher sensitivity and specificity and wider availability. |
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Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update Inflammatory bowel diseaseDiagnosisSerologyFecal markers The inflammatory bowel diseases, consisting of Crohn's disease, ulcerative colitis and indeterminate colitis, are distinguished by idiopathic and chronic inflammation of the digestive tract. The distinction between inflammatory bowel diseases and functional bowel disorders, such as irritable bowel syndrome, can be complex because they often present with similar symptoms. Rapid and inexpensive noninvasive tests that are sensitive, specific and simple are needed to prevent patient discomfort, delay in diagnosis, and unnecessary costs. None of the current commercially available serological biomarker tests can be used as a stand-alone diagnostic in clinics. Instead, these are used as an adjunct to endoscopy in diagnosis and prognosis of the disease.Along these lines,, fecal lactoferrin and calprotectin tests seem to be one step further from other tests with larger number of studies, higher sensitivity and specificity and wider availability. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1841110.1590/S1807-59322010000200015Clinics; Vol. 65 No. 2 (2010); 221-231 Clinics; v. 65 n. 2 (2010); 221-231 Clinics; Vol. 65 Núm. 2 (2010); 221-231 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/18411/20474Turkay, CanselKasapoglu, Benaninfo:eu-repo/semantics/openAccess2012-05-23T11:21:16Zoai:revistas.usp.br:article/18411Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T11:21:16Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
title |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
spellingShingle |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update Turkay, Cansel Inflammatory bowel disease Diagnosis Serology Fecal markers |
title_short |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
title_full |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
title_fullStr |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
title_full_unstemmed |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
title_sort |
Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update |
author |
Turkay, Cansel |
author_facet |
Turkay, Cansel Kasapoglu, Benan |
author_role |
author |
author2 |
Kasapoglu, Benan |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Turkay, Cansel Kasapoglu, Benan |
dc.subject.por.fl_str_mv |
Inflammatory bowel disease Diagnosis Serology Fecal markers |
topic |
Inflammatory bowel disease Diagnosis Serology Fecal markers |
description |
The inflammatory bowel diseases, consisting of Crohn's disease, ulcerative colitis and indeterminate colitis, are distinguished by idiopathic and chronic inflammation of the digestive tract. The distinction between inflammatory bowel diseases and functional bowel disorders, such as irritable bowel syndrome, can be complex because they often present with similar symptoms. Rapid and inexpensive noninvasive tests that are sensitive, specific and simple are needed to prevent patient discomfort, delay in diagnosis, and unnecessary costs. None of the current commercially available serological biomarker tests can be used as a stand-alone diagnostic in clinics. Instead, these are used as an adjunct to endoscopy in diagnosis and prognosis of the disease.Along these lines,, fecal lactoferrin and calprotectin tests seem to be one step further from other tests with larger number of studies, higher sensitivity and specificity and wider availability. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18411 10.1590/S1807-59322010000200015 |
url |
https://www.revistas.usp.br/clinics/article/view/18411 |
identifier_str_mv |
10.1590/S1807-59322010000200015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18411/20474 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 65 No. 2 (2010); 221-231 Clinics; v. 65 n. 2 (2010); 221-231 Clinics; Vol. 65 Núm. 2 (2010); 221-231 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222755286679552 |