Prognostic factors for sperm retrieval in non-obstructive azoospermia
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/53185 |
Resumo: | Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions. |
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Prognostic factors for sperm retrieval in non-obstructive azoospermia AzoospermiaTesticular Sperm RetrievalMale InfertilityReproductive TechniquesPrognosis Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/5318510.6061/clinics/2013(Sup01)13Clinics; Vol. 68 No. spe (2013); 121-124Clinics; v. 68 n. spe (2013); 121-124Clinics; Vol. 68 Núm. spe (2013); 121-1241980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/53185/57246Glina, SidneyVieira, Marceloinfo:eu-repo/semantics/openAccess2013-04-08T20:47:20Zoai:revistas.usp.br:article/53185Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2013-04-08T20:47:20Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
title |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
spellingShingle |
Prognostic factors for sperm retrieval in non-obstructive azoospermia Glina, Sidney Azoospermia Testicular Sperm Retrieval Male Infertility Reproductive Techniques Prognosis |
title_short |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
title_full |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
title_fullStr |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
title_full_unstemmed |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
title_sort |
Prognostic factors for sperm retrieval in non-obstructive azoospermia |
author |
Glina, Sidney |
author_facet |
Glina, Sidney Vieira, Marcelo |
author_role |
author |
author2 |
Vieira, Marcelo |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Glina, Sidney Vieira, Marcelo |
dc.subject.por.fl_str_mv |
Azoospermia Testicular Sperm Retrieval Male Infertility Reproductive Techniques Prognosis |
topic |
Azoospermia Testicular Sperm Retrieval Male Infertility Reproductive Techniques Prognosis |
description |
Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/53185 10.6061/clinics/2013(Sup01)13 |
url |
https://www.revistas.usp.br/clinics/article/view/53185 |
identifier_str_mv |
10.6061/clinics/2013(Sup01)13 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/53185/57246 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 68 No. spe (2013); 121-124 Clinics; v. 68 n. spe (2013); 121-124 Clinics; Vol. 68 Núm. spe (2013); 121-124 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222759770390528 |