Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial

Detalhes bibliográficos
Autor(a) principal: Freitas-Junior, Ruffo
Data de Publicação: 2017
Outros Autores: Ribeiro, Luís Fernando Jubé, Moreira, Marise Amaral Rebouças, Queiroz, Geraldo Silva, Esperidião, Maurício Duarte, Silva, Marco Aurélio Costa, Pereira, Rubens José, Zampronha, Rossana Araújo Catão, Rahal, Rosemar Macedo Sousa, Soares, Leonardo Ribeiro, dos Santos, Danielle Laperche, Thomazini, Maria Virginia, de Faria, Cassiana Ferreira Silva, Paulinelli, Régis Resende
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/135268
Resumo: OBJECTIVE: This randomized clinical trial evaluated the possibility of not draining the axilla following axillary dissection. METHODS: The study included 240 breast cancer patients who underwent axillary dissection as part of conservative treatment. The patients were divided into two groups depending on whether or not they were subjected to axillary drainage. ClinicalTrials.gov: NCT01267552. RESULTS: The median volume of fluid aspirated was significantly lower in the axillary drainage group (0.00 ml; 0.00 - 270.00) compared to the no drain group (522.50 ml; 130.00 - 1148.75). The median number of aspirations performed during conservative breast cancer treatment was significantly lower in the drainage group (0.5; 0.0 - 4.0) compared to the no drain group (5.0; 3.0 - 7.0). The total volume of serous fluid produced (the volume of fluid obtained from drainage added to the volume of aspirated fluid) was similar in the two groups. Regarding complications, two cases (2.4%) of wound dehiscence occurred in the drainage group compared to 13 cases (13.5%) in the group in which drainage was not performed, with this difference being statistically significant. Rates of infection, necrosis and hematoma were similar in both groups. CONCLUSION: Safety rates were similar in both study groups; hence, axillary dissection can feasibly be performed without drainage. However, more needle aspirations could be required, and there could be more cases of wound dehiscence in patients who do not undergo auxiliary drainage.
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spelling Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trialBreast CancerBreast-conserving SurgeryLymph Node ExcisionDrainagePostoperative ComplicationsOBJECTIVE: This randomized clinical trial evaluated the possibility of not draining the axilla following axillary dissection. METHODS: The study included 240 breast cancer patients who underwent axillary dissection as part of conservative treatment. The patients were divided into two groups depending on whether or not they were subjected to axillary drainage. ClinicalTrials.gov: NCT01267552. RESULTS: The median volume of fluid aspirated was significantly lower in the axillary drainage group (0.00 ml; 0.00 - 270.00) compared to the no drain group (522.50 ml; 130.00 - 1148.75). The median number of aspirations performed during conservative breast cancer treatment was significantly lower in the drainage group (0.5; 0.0 - 4.0) compared to the no drain group (5.0; 3.0 - 7.0). The total volume of serous fluid produced (the volume of fluid obtained from drainage added to the volume of aspirated fluid) was similar in the two groups. Regarding complications, two cases (2.4%) of wound dehiscence occurred in the drainage group compared to 13 cases (13.5%) in the group in which drainage was not performed, with this difference being statistically significant. Rates of infection, necrosis and hematoma were similar in both groups. CONCLUSION: Safety rates were similar in both study groups; hence, axillary dissection can feasibly be performed without drainage. However, more needle aspirations could be required, and there could be more cases of wound dehiscence in patients who do not undergo auxiliary drainage.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2017-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/13526810.6061/clinics/2017(07)07Clinics; Vol. 72 No. 7 (2017); 426-431Clinics; v. 72 n. 7 (2017); 426-431Clinics; Vol. 72 Núm. 7 (2017); 426-4311980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/135268/131088Copyright (c) 2017 Clinicsinfo:eu-repo/semantics/openAccessFreitas-Junior, RuffoRibeiro, Luís Fernando JubéMoreira, Marise Amaral RebouçasQueiroz, Geraldo SilvaEsperidião, Maurício DuarteSilva, Marco Aurélio CostaPereira, Rubens JoséZampronha, Rossana Araújo CatãoRahal, Rosemar Macedo SousaSoares, Leonardo Ribeirodos Santos, Danielle LapercheThomazini, Maria Virginiade Faria, Cassiana Ferreira SilvaPaulinelli, Régis Resende2017-08-08T12:48:50Zoai:revistas.usp.br:article/135268Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2017-08-08T12:48:50Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
title Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
spellingShingle Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
Freitas-Junior, Ruffo
Breast Cancer
Breast-conserving Surgery
Lymph Node Excision
Drainage
Postoperative Complications
title_short Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
title_full Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
title_fullStr Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
title_full_unstemmed Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
title_sort Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial
author Freitas-Junior, Ruffo
author_facet Freitas-Junior, Ruffo
Ribeiro, Luís Fernando Jubé
Moreira, Marise Amaral Rebouças
Queiroz, Geraldo Silva
Esperidião, Maurício Duarte
Silva, Marco Aurélio Costa
Pereira, Rubens José
Zampronha, Rossana Araújo Catão
Rahal, Rosemar Macedo Sousa
Soares, Leonardo Ribeiro
dos Santos, Danielle Laperche
Thomazini, Maria Virginia
de Faria, Cassiana Ferreira Silva
Paulinelli, Régis Resende
author_role author
author2 Ribeiro, Luís Fernando Jubé
Moreira, Marise Amaral Rebouças
Queiroz, Geraldo Silva
Esperidião, Maurício Duarte
Silva, Marco Aurélio Costa
Pereira, Rubens José
Zampronha, Rossana Araújo Catão
Rahal, Rosemar Macedo Sousa
Soares, Leonardo Ribeiro
dos Santos, Danielle Laperche
Thomazini, Maria Virginia
de Faria, Cassiana Ferreira Silva
Paulinelli, Régis Resende
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas-Junior, Ruffo
Ribeiro, Luís Fernando Jubé
Moreira, Marise Amaral Rebouças
Queiroz, Geraldo Silva
Esperidião, Maurício Duarte
Silva, Marco Aurélio Costa
Pereira, Rubens José
Zampronha, Rossana Araújo Catão
Rahal, Rosemar Macedo Sousa
Soares, Leonardo Ribeiro
dos Santos, Danielle Laperche
Thomazini, Maria Virginia
de Faria, Cassiana Ferreira Silva
Paulinelli, Régis Resende
dc.subject.por.fl_str_mv Breast Cancer
Breast-conserving Surgery
Lymph Node Excision
Drainage
Postoperative Complications
topic Breast Cancer
Breast-conserving Surgery
Lymph Node Excision
Drainage
Postoperative Complications
description OBJECTIVE: This randomized clinical trial evaluated the possibility of not draining the axilla following axillary dissection. METHODS: The study included 240 breast cancer patients who underwent axillary dissection as part of conservative treatment. The patients were divided into two groups depending on whether or not they were subjected to axillary drainage. ClinicalTrials.gov: NCT01267552. RESULTS: The median volume of fluid aspirated was significantly lower in the axillary drainage group (0.00 ml; 0.00 - 270.00) compared to the no drain group (522.50 ml; 130.00 - 1148.75). The median number of aspirations performed during conservative breast cancer treatment was significantly lower in the drainage group (0.5; 0.0 - 4.0) compared to the no drain group (5.0; 3.0 - 7.0). The total volume of serous fluid produced (the volume of fluid obtained from drainage added to the volume of aspirated fluid) was similar in the two groups. Regarding complications, two cases (2.4%) of wound dehiscence occurred in the drainage group compared to 13 cases (13.5%) in the group in which drainage was not performed, with this difference being statistically significant. Rates of infection, necrosis and hematoma were similar in both groups. CONCLUSION: Safety rates were similar in both study groups; hence, axillary dissection can feasibly be performed without drainage. However, more needle aspirations could be required, and there could be more cases of wound dehiscence in patients who do not undergo auxiliary drainage.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/135268
10.6061/clinics/2017(07)07
url https://www.revistas.usp.br/clinics/article/view/135268
identifier_str_mv 10.6061/clinics/2017(07)07
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/135268/131088
dc.rights.driver.fl_str_mv Copyright (c) 2017 Clinics
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Clinics
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 72 No. 7 (2017); 426-431
Clinics; v. 72 n. 7 (2017); 426-431
Clinics; Vol. 72 Núm. 7 (2017); 426-431
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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